Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Clint A. Stalnecker"'
Autor:
Andrew M. Waters, Tala O. Khatib, Bjoern Papke, Craig M. Goodwin, G. Aaron Hobbs, J. Nathaniel Diehl, Runying Yang, A. Cole Edwards, Katherine H. Walsh, Rita Sulahian, James M. McFarland, Kevin S. Kapner, Thomas S.K. Gilbert, Clint A. Stalnecker, Sehrish Javaid, Anna Barkovskaya, Kajal R. Grover, Priya S. Hibshman, Devon R. Blake, Antje Schaefer, Katherine M. Nowak, Jennifer E. Klomp, Tikvah K. Hayes, Michelle Kassner, Nanyun Tang, Olga Tanaseichuk, Kaisheng Chen, Yingyao Zhou, Manpreet Kalkat, Laura E. Herring, Lee M. Graves, Linda Z. Penn, Hongwei H. Yin, Andrew J. Aguirre, William C. Hahn, Adrienne D. Cox, Channing J. Der
Publikováno v:
Cell Reports, Vol 35, Iss 13, Pp 109291- (2021)
Summary: To identify therapeutic targets for KRAS mutant pancreatic cancer, we conduct a druggable genome small interfering RNA (siRNA) screen and determine that suppression of BCAR1 sensitizes pancreatic cancer cells to ERK inhibition. Integrative a
Externí odkaz:
https://doaj.org/article/24ff658919d8494e80b28117e73c541b
Autor:
Ye S. Lee, Jennifer E. Klomp, Clint A. Stalnecker, Craig M. Goodwin, Yanzhe Gao, Gaith N. Droby, Cyrus Vaziri, Kirsten L. Bryant, Channing J. Der, Adrienne D. Cox
Publikováno v:
Genes & Cancer. 14:30-49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf5c98db1c2f6adfe62574239278d9a
https://doi.org/10.18632/genesandcancer.231
https://doi.org/10.18632/genesandcancer.231
Autor:
Craig M. Goodwin, Andrew M. Waters, Jennifer E. Klomp, Sehrish Javaid, Kirsten L. Bryant, Clint A. Stalnecker, Kristina Drizyte-Miller, Bjoern Papke, Runying Yang, Amber M. Amparo, Irem Ozkan-Dagliyan, Elisa Baldelli, Valerie Calvert, Mariaelena Pierobon, Jessica A. Sorrentino, Andrew P. Beelen, Natalie Bublitz, Mareen Lüthen, Kris C. Wood, Emanuel F. Petricoin, Christine Sers, Autumn J. McRee, Adrienne D. Cox, Channing J. Der
Publikováno v:
Cancer Res
Mutational loss of CDKN2A (encoding p16INK4A) tumor-suppressor function is a key genetic step that complements activation of KRAS in promoting the development and malignant growth of pancreatic ductal adenocarcinoma (PDAC). However, pharmacologic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cab7d8277df82fc4e157bfc7db0ef82
https://doi.org/10.1158/0008-5472.can-22-0391
https://doi.org/10.1158/0008-5472.can-22-0391
Autor:
Channing J. Der, Adrienne D. Cox, Autumn J. McRee, Christine Sers, Emanuel F. Petricoin, Kris C. Wood, Mareen Lüthen, Natalie Bublitz, Andrew P. Beelen, Jessica A. Sorrentino, Mariaelena Pierobon, Valerie Calvert, Elisa Baldelli, Irem Ozkan-Dagliyan, Amber M. Amparo, Runying Yang, Bjoern Papke, Kristina Drizyte-Miller, Clint A. Stalnecker, Kirsten L. Bryant, Sehrish Javaid, Jennifer E. Klomp, Andrew M. Waters, Craig M. Goodwin
Figure S7 page2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acddd6baeccef281cd7c89ad06c366e
https://doi.org/10.1158/0008-5472.22432947
https://doi.org/10.1158/0008-5472.22432947
Autor:
Kirsten L. Bryant, Stephen D. Hursting, Channing J. Der, Adrienne D. Cox, Krister Wennerberg, Prson Gautam, Emanuel F. Petricoin, Mariaelena Pierobon, Craig M. Goodwin, Björn Papke, Jonathan M. DeLiberty, Runying Yang, Michael F. Coleman, A. Cole Edwards, Kajal R. Grover, Clint A. Stalnecker
Supplementary Figure from Concurrent Inhibition of IGF1R and ERK Increases Pancreatic Cancer Sensitivity to Autophagy Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163c0671121a747c0511762384eaab20
https://doi.org/10.1158/0008-5472.22431325.v1
https://doi.org/10.1158/0008-5472.22431325.v1
Autor:
Channing J. Der, Adrienne D. Cox, Autumn J. McRee, Christine Sers, Emanuel F. Petricoin, Kris C. Wood, Mareen Lüthen, Natalie Bublitz, Andrew P. Beelen, Jessica A. Sorrentino, Mariaelena Pierobon, Valerie Calvert, Elisa Baldelli, Irem Ozkan-Dagliyan, Amber M. Amparo, Runying Yang, Bjoern Papke, Kristina Drizyte-Miller, Clint A. Stalnecker, Kirsten L. Bryant, Sehrish Javaid, Jennifer E. Klomp, Andrew M. Waters, Craig M. Goodwin
Supplementary Data and Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306f3e6cb9bdc08cf8212e98818fdca1
https://doi.org/10.1158/0008-5472.22432941
https://doi.org/10.1158/0008-5472.22432941
Autor:
Channing J. Der, Adrienne D. Cox, Autumn J. McRee, Christine Sers, Emanuel F. Petricoin, Kris C. Wood, Mareen Lüthen, Natalie Bublitz, Andrew P. Beelen, Jessica A. Sorrentino, Mariaelena Pierobon, Valerie Calvert, Elisa Baldelli, Irem Ozkan-Dagliyan, Amber M. Amparo, Runying Yang, Bjoern Papke, Kristina Drizyte-Miller, Clint A. Stalnecker, Kirsten L. Bryant, Sehrish Javaid, Jennifer E. Klomp, Andrew M. Waters, Craig M. Goodwin
Mutational loss of CDKN2A (encoding p16INK4A) tumor-suppressor function is a key genetic step that complements activation of KRAS in promoting the development and malignant growth of pancreatic ductal adenocarcinoma (PDAC). However, pharmacologic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aac2b4a73c2414e8aceef7834205187
https://doi.org/10.1158/0008-5472.c.6514275.v1
https://doi.org/10.1158/0008-5472.c.6514275.v1
Autor:
Kirsten L. Bryant, Stephen D. Hursting, Channing J. Der, Adrienne D. Cox, Krister Wennerberg, Prson Gautam, Emanuel F. Petricoin, Mariaelena Pierobon, Craig M. Goodwin, Björn Papke, Jonathan M. DeLiberty, Runying Yang, Michael F. Coleman, A. Cole Edwards, Kajal R. Grover, Clint A. Stalnecker
The aggressive nature of pancreatic ductal adenocarcinoma (PDAC) mandates the development of improved therapies. As KRAS mutations are found in 95% of PDAC and are critical for tumor maintenance, one promising strategy involves exploiting KRAS-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe92f59ec4caa6cc2e5657a516fd0f49
https://doi.org/10.1158/0008-5472.c.6513874.v1
https://doi.org/10.1158/0008-5472.c.6513874.v1
Autor:
Channing J. Der, Adrienne D. Cox, Autumn J. McRee, Christine Sers, Emanuel F. Petricoin, Kris C. Wood, Mareen Lüthen, Natalie Bublitz, Andrew P. Beelen, Jessica A. Sorrentino, Mariaelena Pierobon, Valerie Calvert, Elisa Baldelli, Irem Ozkan-Dagliyan, Amber M. Amparo, Runying Yang, Bjoern Papke, Kristina Drizyte-Miller, Clint A. Stalnecker, Kirsten L. Bryant, Sehrish Javaid, Jennifer E. Klomp, Andrew M. Waters, Craig M. Goodwin
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9063a982801a1d99eae9d4209128101a
https://doi.org/10.1158/0008-5472.22432938
https://doi.org/10.1158/0008-5472.22432938
Autor:
Alexander C. Edwards, Clint A. Stalnecker, Alexis J. Morales, Khalilah E. Taylor, Jill Hallin, Peter Olson, Tracy T. Tang, Lars Engstrom, Leonard Post, James G. Christensen, Adrienne D. Cox, Channing J. Der
Publikováno v:
Molecular Cancer Research. 21:B009-B009
Activated mutants of KRAS comprise the major oncogenic drivers in lung (LAC), colorectal (CRC), and pancreatic ductal (PDAC) adenocarcinoma. Recent success in covalently targeting one KRAS mutant (KRASG12C) led to FDA approval of the first anti-KRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec313a8b3455001e6764488b93137d59
https://doi.org/10.1158/1557-3125.ras23-b009
https://doi.org/10.1158/1557-3125.ras23-b009