Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Clinical and Human Immunology"'
1
Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus
Autor: Qing Zhang, Yu Liu, Jieyue Liao, Ruifang Wu, Yi Zhan, Peng Zhang, Shuangyan Luo
Publikováno v: J Immunol
Underexpression of p53 is considered the leading cause of the decreased miR-1246 expression in B cells of systemic lupus erythematosus (SLE) patients, yet the exact mechanism of action still remains unclear. To further explore the molecular mechanism
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9fd8918b010521dfc05d037efaa5a5
https://doi.org/10.4049/jimmunol.2200307
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2
Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation
Autor: Charles Kyriakos Vorkas, Chirag Krishna, Kelin Li, Jeffrey Aubé, Daniel W. Fitzgerald, Linas Mazutis, Christina S. Leslie, Michael S. Glickman
Publikováno v: J Immunol
Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes that recognize microbial vitamin B metabolites and have emerging roles in infectious disease, autoimmunity, and cancer. Although MAIT cells are identified by a semi-invariant TCR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f020bd0d0f90a73d718d3d9107bbec7d
https://doi.org/10.4049/jimmunol.2100522
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3
Bidirectional Transport of IgE by CD23 in the Inner Ear of Patients with Meniere’s Disease
Autor: Na Zhang, Yafeng Lyu, Jia Guo, Jiahui Liu, Yongdong Song, Zhaomin Fan, Xiaofei Li, Na Li, Daogong Zhang, Haibo Wang
Publikováno v: J Immunol
Meniere’s disease (MD) is a disorder of the inner ear characterized by episodes of spontaneous vertigo, fluctuating hearing loss, and tinnitus. Recent studies have demonstrated that IgE may play a role in the pathogenesis of MD. Patients with MD (n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cddba586e596429c629513590601bf3
https://doi.org/10.4049/jimmunol.2100745
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4
Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination
Autor: Breznik, Jessica A., Huynh, Angela, Zhang, Ali, Bilaver, Lucas, Bhakta, Hina, Stacey, Hannah D., Ang, Jann C., Bramson, Jonathan L., Nazy, Ishac, Miller, Matthew S., Denburg, Judah, Costa, Andrew P., Bowdish, Dawn M. E.
Publikováno v: J Immunol
Chronic infection with human CMV may contribute to poor vaccine efficacy in older adults. We assessed the effects of CMV serostatus on Ab quantity and quality, as well as cellular memory recall responses, after two and three SARS-CoV-2 mRNA vaccine d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aead0bf2957aaae167ace847b06e5f8
https://europepmc.org/articles/PMC9666329/
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5
Correction: Maternal Monocytes Respond to Cell-Free Fetal DNA and Initiate Key Processes of Human Parturition
Publikováno v: J Immunol
Throughout gestation, the maternal immune system is tightly modulated to allow growth of a semiallogeneic fetus. During the third trimester, the maternal immune system shifts to a proinflammatory phenotype in preparation for labor. What induces this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ef25adccc795b72e1b7141042ece8d6
https://pubmed.ncbi.nlm.nih.gov/34663619
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6
Activation and Kinetics of Circulating T Follicular Helper Cells, Specific Plasmablast Response, and Development of Neutralizing Antibodies following Yellow Fever Virus Vaccination
Autor: Kim Blom, Ola Nilsson, Markus Kalén, Lars Rombo, Hans-Gustaf Ljunggren, Renata Varnaitė, Sebastian Ols, Karin Loré, Marie Löfling, John Tyler Sandberg, Gustaf Lindgren
Publikováno v: J Immunol
A single dose of the replication-competent, live-attenuated yellow fever virus (YFV) 17D vaccine provides lifelong immunity against human YFV infection. The magnitude, kinetics, and specificity of B cell responses to YFV 17D are relatively less under
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1734482d78d0225ba69b718d2ae0a4a5
https://doi.org/10.4049/jimmunol.2001381
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7
Low Vitamin D Status Is Associated with Inflammation in Patients with Chronic Obstructive Pulmonary Disease
Autor: Hui-Xiang Xiang, Biao Hu, De-Xiang Xu, Jun Fei, Zhu-Xia Tan, Yuan-Hua Chen, Hui Zhao, Lin Fu
Publikováno v: J Immunol
Vitamin D deficiency is associated with increased risks of chronic obstructive pulmonary disease (COPD). Nevertheless, the mechanisms remain unknown. This study analyzed the correlations between vitamin D levels and inflammation in COPD patients. One
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab66acf660f2d807e5dfb77f5fa9983
https://doi.org/10.4049/jimmunol.2000964
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9
The Kinetics of COVID-19 Vaccine Response in a Community Vaccinated Population
Autor: Samantha H. Chiang, Charles M. Strom, Michael Tu, David T.W. Wong, Richard A. Bender
Publikováno v: J Immunol
medRxiv
article-version (status) pre
article-version (number) 1
We used a noninvasive electrochemical quantitative assay for IgG antibodies to SARS-CoV-2 S1 in saliva to investigate the kinetics of antibody response in a community-based population who had received either the Pfizer or Moderna mRNA-based vaccines.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697e462da5a9fbd4c895d49025ebcc74
https://pubmed.ncbi.nlm.nih.gov/35039333
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10
Maternal and Infant Immune Repertoire Sequencing Analysis Identifies Distinct Ig and TCR Development in Term and Preterm Infants
Autor: Marina Sirota, Ji-Yeun Lee, Quoc-Hung Nguyen, Scott D. Boyd, Brian L. Le, Renan Sper, Sandra C. A. Nielsen, Tippi C. MacKenzie, Silvia Pineda
Publikováno v: J Immunol
Journal of immunology (Baltimore, Md. : 1950), vol 207, iss 10
Preterm labor (PTL) is the leading cause of neonatal morbidity and mortality worldwide. Whereas many studies have investigated the maternal immune responses that cause PTL, fetal immune cell activation has recently been raised as an important contrib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a27874f6150b67b97e9e8388146c55
https://pubmed.ncbi.nlm.nih.gov/34654689
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