Quantitative assessment of the exposure-efficacy relationship of glucocerebrosidase using Markovian elements in Gaucher patients treated with enzyme replacement therapy

Autor: Gras-Colomer E, Mangas-Sanjuán V, Martínez-Gómez MA, Climente-Martí M, Merino-Sanjuan M

Publikováno v: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
r-FISABIO. Repositorio Institucional de Producción Científica
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AIMS: The aims of this study are (i) to develop a population pharmacokinetic model of enzyme activity in Gaucher-type 1 (GD1) patients after intravenous administration of enzyme replacement therapy (ERT), and (ii) to establish an exposure-efficacy re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::0aa74a9fdc9ac6456f523889a2ecd75a
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=12537

Doctors’ acceptance of recommendations for patients with the opportunity for pharmacotherapy improvement

Autor: López-Montenegro Soria, M.A., Climente Martí, M., Jiménez Torres, N.V.

Publikováno v: In Farmacia Hospitalaria (English Edition) 2011 35(2):51-57

Evaluation of ABC gene polymorphisms on the pharmacokinetics and pharmacodynamics of capecitabine in colorectal patients: Implications for dosing recommendations

Autor: Sáez-Belló M, Mangas-Sanjuán V, Martínez-Gómez MA, López-Montenegro Soria MÁ, Climente-Martí M, Merino-Sanjuán M

Publikováno v: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname

Aims The aims are to develop a population pharmacokinetic model of capecitabine (CAP) and its main metabolites after the oral administration of CAP in colorectal cancer patients with different polymorphisms of the ATP-binding cassette (ABC) gene and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::63e70805a1690ff108badca5905d3c3f
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7503

Effectiveness and Safety of Methylprednisolone When Treating Patients with COVID-19 Pneumonia-Induced Severe Systemic Inflammation: A Retrospective, Cohort Study

Autor: Ruiz-Millo O, Pitarch Jvl, López-Estudillo R, Coito Jmn, González Tr, Gómez Eg, Climente-Martí M, Crespo Rz, Sinisterra Fd, Atienza-García Á, Martínez-Moragón E, Rentero Db, Cruz Il, Serrano Rr, López-Grima Ml, Artal Mam

Publikováno v: SSRN Electronic Journal.

Background: This study aimed to evaluate the effectiveness and safety of intermediate to high doses of methylprednisolone in patients with COVID-19 pneumonia-induced severe systemic inflammation (PI-SSI). Methods: Between March, 9 and May, 5, 2020 (f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26989ef969305f1ed28d60c9c92cd386
https://doi.org/10.2139/ssrn.3756801

Clinical utility of serum concentrations of adalimumab as predictor of treatment adherence

Autor: Sáez Belló M, Llopis Salvia P, Alegre Sancho JJ, Paredes Arquiola JM, Asencio Muñoz MDC, Climente Martí M

Publikováno v: Reumatologia Clinica
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Objective: to evaluate the usefulness of serum concentrations (Sc) of adalimumab (ADA) as a predictor of medication adherence using the medication possession ratio (MPR) and Morisky Green test (MGT) in patients with chronic inflammatory diseases. Mat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::484efbda13fda12d10e18ecfd7158649
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=3186