Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Clifton McPherson"'
Autor:
Yoshifumi Hashimoto, Daniel Macri, Indresh Srivastava, Clifton McPherson, Rachael Felberbaum, Penny Post, Manon Cox
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175633 (2017)
A putative novel rhabdovirus (SfRV) was previously identified in a Spodoptera frugiperda cell line (Sf9 cells [ATCC CRL-1711 lot 58078522]) by next generation sequencing and extensive bioinformatic analysis. We performed an extensive analysis of our
Externí odkaz:
https://doaj.org/article/00da46c955544cc98d24e3e4fb04ae13
Autor:
Manon M.J. Cox, Clifton McPherson, Barry Buckland, Mireli Fino, Kathy Holtz, Indresh K. Srivastava, Paul Kubera, Nikolai Khramtsov, Jamal Meghrous, Robert Boulanger
Publikováno v:
Vaccine. 32:5496-5502
Multiple different hemagglutinin (HA) protein antigens have been reproducibly manufactured at the 650L scale by Protein Sciences Corporation (PSC) based on an insect cell culture with baculovirus infection. Significantly, these HA protein antigens we
Autor:
Clifton, McPherson, Richard, Chubet, Kathy, Holtz, Yoshikazu, Honda-Okubo, Dale, Barnard, Manon, Cox, Nikolai, Petrovsky
Publikováno v:
Vaccine Design
Given periodic outbreaks of fatal human infections caused by coronaviruses, development of an optimal coronavirus vaccine platform capable of rapid production is an ongoing priority. This chapter describes the use of an insect cell expression system
Autor:
Nikolai Petrovsky, Clifton McPherson, Manon M.J. Cox, Richard Chubet, Kathy Holtz, Yoshikazu Honda-Okubo, Dale L. Barnard
Publikováno v:
Vaccine Design ISBN: 9781493933853
Given periodic outbreaks of fatal human infections caused by coronaviruses, development of an optimal coronavirus vaccine platform capable of rapid production is an ongoing priority. This chapter describes the use of an insect cell expression system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8014a6812ee283095aef487a4b8cd538
https://doi.org/10.1007/978-1-4939-3387-7_14
https://doi.org/10.1007/978-1-4939-3387-7_14
Autor:
Clifton McPherson
Publikováno v:
Biologicals. 36:350-353
Influenza is a highly contagious viral respiratory illness which is best prevented through vaccination. Currently, all US licensed influenza vaccines are produced in embryonated chicken eggs. The Baculovirus Expression Vector System (BEVS) technology
Autor:
Keyang Wang, Clifton McPherson, Pam Robinson, Kathy Holtz, Indresh K. Srivastava, David G. Rhodes, Manon M.J. Cox
Publikováno v:
Vaccine. 33(44)
This study was designed to improve the stability of liquid formulations of recombinant influenza hemagglutinin (rHA) and to understand the mechanism of early loss of potency for rHA. The potency of rHA derived from several influenza strains was deter
Autor:
Clifton McPherson, Yoshifumi Hashimoto, Manon M.J. Cox, Rachael Felberbaum, Daniel Macri, Penny Post, Indresh K. Srivastava
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175633 (2017)
PLoS ONE
PLoS ONE
A putative novel rhabdovirus (SfRV) was previously identified in a Spodoptera frugiperda cell line (Sf9 cells [ATCC CRL-1711 lot 58078522]) by next generation sequencing and extensive bioinformatic analysis. We performed an extensive analysis of our
Autor:
Kathleen Holtz, Indresh K. Srivastava, Yoshifumi Hashimoto, Nikolai Khramtsov, Michael J Reifler, Jamal Meghrous, Pamela S Robinson, David G. Rhodes, Manon M.J. Cox, Erin Matthews, Clifton McPherson
Publikováno v:
BMC Biotechnology
Background Recombinant hemagglutinin (rHA) is the active component in Flublok®; a trivalent influenza vaccine produced using the baculovirus expression vector system (BEVS). HA is a membrane bound homotrimer in the influenza virus envelope, and the
Autor:
David B. Volkin, Clifton McPherson, Prakash Manikwar, John M. Hickey, C. Russell Middaugh, Barry Buckland, Indresh K. Srivastava, Kathleen Holtz, Sangeeta B. Joshi
Publikováno v:
Journal of pharmaceutical sciences. 103(3)
The recombinant hemagglutinin (rHA)-based influenza vaccine Flublok® has recently been approved in the United States as an alternative to the traditional egg-derived flu vaccines. Flublok is a purified vaccine with a hemagglutinin content that is th
Autor:
Clifton McPherson, Elena Feshchenko, Rachael Felberbaum, David G. Rhodes, Manon M.J. Cox, Joseph A. Rininger, Penny Post
Publikováno v:
BMC Biotechnology, Vol 12, Iss 1, p 77 (2012)
BMC Biotechnology
BMC Biotechnology
Background The recent H1N1 influenza pandemic illustrated the shortcomings of the vaccine manufacturing process. The A/California/07/2009 H1N1 pandemic influenza vaccine or A(H1N1)pdm09 was available late and in short supply as a result of delays in