Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Clifton L. Ricaña"'
Autor:
Clifton L. Ricaña, Robert A. Dick
Publikováno v:
Viruses, Vol 13, Iss 12, p 2516 (2021)
Understanding the molecular mechanisms of retroviral assembly has been a decades-long endeavor. With the recent discovery of inositol hexakisphosphate (IP6) acting as an assembly co-factor for human immunodeficiency virus (HIV), great strides have be
Externí odkaz:
https://doaj.org/article/230ca6c9cef94604bb7effcbe8834eff
The HIV-1 capsid houses the viral genome and interacts extensively with host cell proteins throughout the viral life cycle. It is composed of capsid protein (CA), which assembles into a conical fullerene lattice composed of roughly 200 CA hexamers an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab9655a8aec0d66beecd359f8fbeb8f
https://doi.org/10.1101/2022.12.02.518872
https://doi.org/10.1101/2022.12.02.518872
Autor:
Martin Obr, Clifton L. Ricana, Nadia Nikulin, Jon-Philip R. Feathers, Marco Klanschnig, Andreas Thader, Marc C. Johnson, Volker M. Vogt, Florian K. M. Schur, Robert A. Dick
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Inositol hexakisphosphate (IP6) is a known assembly cofactor for HIV-1. Here, the authors show the role of IP6 in the assembly of the Rous sarcoma virus (RSV). Reported cryo-ET structures of mature capsid-like particles (CLPs) suggest that IP6 modula
Externí odkaz:
https://doaj.org/article/8367c143cb65471aa8e3f6f874525a62