Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Clifton E. McPherson"'
Autor:
Xin-Ming Ma, Jacqueline A. Sobota, Yanping Wang, Martin R. Schiller, Noraisha I. Schiller, Betty A. Eipper, Francesco Ferraro, Clifton E. McPherson, Richard E. Mains
Publikováno v:
Experimental Cell Research. 314:2674-2691
Kalirin is a GDP/GTP exchange factor (GEF) for Rho proteins that modulates the actin cytoskeleton in neurons. Alternative splicing generates Delta-isoforms, which encode the RhoGEF domain, but lack the N-terminal Sec14p domain and first 4 spectrin-li
Publikováno v:
Gene. 284:41-51
Multidomain guanine nucleotide (GDP/GTP) exchange factor (GEF) proteins coordinate diverse inputs that signal the actin cytoskeleton. Mammals have two such proteins (Kalirin, Trio), while Drosophila has one, which plays essential roles within and out
Publikováno v:
Developmental Biology. 221(1):220-232
We have investigated the expression and regulation of the mRNAs for the type I BMP receptors, BMPR-IA and BMPR-IB, in quail embryos in vivo and in neural crest cultures in vitro. BMPR-IB mRNA was expressed in the primordial sympathetic ganglia at sta
Publikováno v:
Journal of Neuroscience Research. 56:248-258
Similarities between primitive neuroectodermal tumors and central nervous system (CNS) progenitor cells have evoked interest in the response of these tumors to endogenous growth factors. The bone morphogenetic proteins (BMPs) have recently been found
Publikováno v:
Developmental Biology. 196:107-118
Previous work has demonstrated that the bone morphogenetic proteins (BMP)-2, BMP-4, and BMP-7 can promote the development of tyrosine hydroxylase (TH)-positive and catecholamine-positive cells in quail trunk neural crest cultures. In the present work
Publikováno v:
Methods. 11:180-188
Regulatory factors important for the developmental control of genes have been identified by genetic studies or by examining the ontological expression profiles of proteins that were originally characterized in adult tissues; direct biochemical studie
Publikováno v:
Cell. 75:387-398
Nucleosomes positioned over promoters are usually inhibitory to protein binding and activity. We analyzed at the nucleotide level of resolution the nucleosomal organization of a distal, liver-specific enhancer in various mouse tissues and found that
Publikováno v:
Biochemical Systematics and Ecology. 20:317-324
The V4 gene of Dictyostelium discoideum is thought to play a role in the transition from amoebal growth to multicellular development. In addition to being rapidly deactivated upon the onset of development, the two corresponding mRNAs show differentia
Publikováno v:
Gene. 347(1)
Mammalian Trio is a multifunctional, multidomain Rho guanine nucleotide exchange factor (GEF) closely related to Kalirin. Trio is important for proper axon guidance in Drosophila, and mice lacking Trio exhibit both skeletal muscle and neuronal disord
Publikováno v:
Journal of molecular neuroscience : MN. 22(1-2)
Kalirin is a multidomain guanine nucleotide exchange factor for small GTP binding proteins of the Rho family. It is expressed in multiple isoforms that contain different combinations of functional domains and display a complex pattern of expression d