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Akademický článek

Decitabine cytotoxicity is promoted by dCMP deaminase DCTD and mitigated by SUMO-dependent E3 ligase TOPORS.

Autor: Carnie CJ; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. chris.carnie@cruk.cam.ac.uk.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK. chris.carnie@cruk.cam.ac.uk., Götz MJ; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Palma-Chaundler CS; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Weickert P; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Wanders A; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Serrano-Benitez A; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Li HY; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Gupta V; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Awwad SW; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Blum CJ; Institute of Molecular Biology (IMB), Mainz, Germany., Sczaniecka-Clift M; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Cordes J; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Zagnoli-Vieira G; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., D'Alessandro G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Richards SL; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Gueorguieva N; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Lam S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Beli P; Institute of Molecular Biology (IMB), Mainz, Germany.; Institute of Developmental Biology and Neurobiology (IDN), Johannes Gutenberg-Universität, Mainz, Germany., Stingele J; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany. stingele@genzentrum.lmu.de., Jackson SP; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. steve.jackson@cruk.cam.ac.uk.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK. steve.jackson@cruk.cam.ac.uk.

Publikováno v: The EMBO journal [EMBO J] 2024 Jun; Vol. 43 (12), pp. 2397-2423. Date of Electronic Publication: 2024 May 17.

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Akademický článek

Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB.

Autor: Carnie CJ; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. chris.carnie@cruk.cam.ac.uk.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK. chris.carnie@cruk.cam.ac.uk., Acampora AC; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Bader AS; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Erdenebat C; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Zhao S; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Bitensky E; Department of Microbiology and Molecular Genetics, The Institute for Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., van den Heuvel D; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Parnas A; Department of Microbiology and Molecular Genetics, The Institute for Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Gupta V; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., D'Alessandro G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Sczaniecka-Clift M; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Weickert P; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Aygenli F; Institute of Medical Psychology and Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany., Götz MJ; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Cordes J; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Esain-Garcia I; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Melidis L; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Wondergem AP; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Lam S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK., Robles MS; Institute of Medical Psychology and Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany., Balasubramanian S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Adar S; Department of Microbiology and Molecular Genetics, The Institute for Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Luijsterburg MS; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Jackson SP; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. steve.jackson@cruk.cam.ac.uk.; The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK. steve.jackson@cruk.cam.ac.uk., Stingele J; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany. stingele@genzentrum.lmu.de.

Publikováno v: Nature cell biology [Nat Cell Biol] 2024 May; Vol. 26 (5), pp. 797-810. Date of Electronic Publication: 2024 Apr 10.

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