Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Clifford Yen"'
Autor:
Steven I. Wang, Ramon Parsons, Michael Ittmann, Beppino C. Giovanella, Linda Rodgers, Janusz Puc, Jing Li, Christa Miliaresis, B. Tycko, Richard W. McCombie, Michael Wigler, Sandra H. Bigner, Katrina Podsypanina, Clifford Yen, Hanina Hibshoosh, Shikha Bose, Danny Liaw
Publikováno v:
Science. 275:1943-1947
Mapping of homozygous deletions on human chromosome 10q23 has led to the isolation of a candidate tumor suppressor gene, PTEN , that appears to be mutated at considerable frequency in human cancers. In preliminary screens, mutations of PTEN were dete
Autor:
Clifford Yen, Joan Alexander, Mariko Nakamura, Andy Reiner, Michael Wigler, Joe West, Robert Lucito
Publikováno v:
Nature Genetics. 23:60-60
We have explored using DNA microarrays for measuring gene copy number in cancer biopsies. The high nucleotide complexity of the human genome makes hybridization analysis of the entire genome problematic. Therefore, we have used the approach of making
Autor:
Timothy Hoey, Ken C. Q. Nguyen, Lori Spiegel, W. Richard McCombie, Liyun Chen, Clifford Yen, Lin Pei, Scott Powers, Jeffrey R. Marks, Christina M Koch, James Jiayuan Tong, Yue Peng, Scott W. Lowe, Lily Yeh Jan, Xi-Ping Zhang, Michael Wigler, Lei-Hoon See, Allyson Servoss, David Mu
Publikováno v:
Cancer Cell. (3):297-302
Representational difference analysis (RDA) of human breast cancer was used to discover a novel amplicon located at chromosomal region 8q24.3. We examined a series of breast cancer samples harboring amplification of this region and determined that KCN