Výsledky vyhledávání - "Clifford R. Roberts"

Monitoring the Health Status of Mice with Bleomycin-induced Lung Injury by Using Body Condition Scoring

Autor: Patrick M. Cowley, Anthony J. Baker, Clifford R. Roberts

Publikováno v: Comparative Medicine. 69:95-102

Well-defined, humane endpoints aid in monitoring animal health status during disease development. Body condition scoring (BCS) is a method for assessing health status in mouse studies where wasting and death are potential endpoints. Whether BCS is us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063d435f808495abb035e275feead213
https://doi.org/10.30802/aalas-cm-18-000060

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Retrospective Analysis of the Effects of Identification Procedures and Cage Changing by Using Data from Automated, Continuous Monitoring

Autor: Evelyn A Jaime, David L Hutto, Jordan A Mechanic, Maria A Lim, Erwin Defensor, Clifford R Roberts, Laura Schaevitz, Puja P Shah

Publikováno v: Journal of the American Association for Laboratory Animal Science : JAALAS. 58(2)

Many variables can influence animal behavior and physiology, potentially affecting scientific study outcomes. Laboratory and husbandry procedures—including handling, cage cleaning, injections, blood collection, and animal identification—may produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2c8e693584185599060b2639c4b246
https://pubmed.ncbi.nlm.nih.gov/30764898

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Importing Human Pluripotent Stem Cell Lines Derived at Another Institution: Tailoring Review to Ethical Concerns

Autor: Christopher Broom, William Hershon, Arnold R. Kriegstein, Pui-Yan Kwok, Michelle Oberman, Richard M. Wagner, Marcelle I. Cedars, Lindsay Parham, Elena Gates, Linda C. Giudice, Dina Gould Halme, Clifford R. Roberts, Bernard Lo

Publikováno v: Cell Stem Cell. 4(2):115-123

Stem cell researchers commonly use human pluripotent stem cell lines derived by other investigators. Researchers may use lines derived elsewhere, provided that their derivation met consensus core standards. Some types of derivation raise heightened l

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Prevalence of Plasmodium falciparum pfcrt polymorphisms and in vitro chloroquine sensitivity in Senegal

Autor: Thérèse Dieng, Susan M. Thomas, Dyann F. Wirth, S. Mboup, Johanna P. Daily, Omar Ndir, Clifford R. Roberts

Publikováno v: Parasitology. 126:401-405

Mutations in pfcrt K76T are associated with chloroquine resistance in Plasmodium falciparum. Previous studies of K76T mutations in Senegal reported the association of T76 with in vitro-resistant isolates, but this mutation was also prevalent in chlor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ec635cff86661aa8040fdd5ff20a1c
https://doi.org/10.1017/s0031182003002981

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Phlebotomine sand fly (Diptera: Psychodidae) seasonal distribution and infection rates in a defined focus of Leishmania tropica

Autor: J.I. Githure, R.N. Johnson, Clifford R. Roberts, Philip M. Ngumbi, Yemane B. Mebrahtu, J.P. Mwanyumba, N C Mosonik, S J Makasa, Phillip G. Lawyer

Publikováno v: The American Journal of Tropical Medicine and Hygiene. 60:854-858

A two-year study was conducted of phlebotomine sand fly fauna in a defined focus of Leishmania tropica. A total of 17,947 sand flies representing 10 species were collected from the location. Phlebotomus guggisbergi, a vector of L. tropica in Kenya, w

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https://doi.org/10.4269/ajtmh.1999.60.854

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Plasmodium falciparum circumsporozoite vaccine immunogenicity and efficacy trial with natural challenge quantitation in an area of endemic human malaria of Kenya

Autor: Charles N. Oster, Clifford R. Roberts, Robert S. Copeland, M. Gross, Jerald C. Sadoff, W. R. Ballou, Aggrey J. Oloo, J.U. Que, K. Abok, J. Wittes, J.B.O. Were, G.T. Strickland, Stanley J. Cryz, K.A. Taylor, J. A. Sherwood, J.D. Bales, Daniel M. Gordon, Robert A. Wirtz

Publikováno v: Vaccine. 14:817-827

It has been hypothesized that antibody induced by Plasmodium falciparum circumsporozoite protein vaccine would be effective against endemic human malaria. In a malaria endemic region of Kenya, 76 volunteers, in 38 pairs sleeping adjacently, were immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a425718508d3097452bb7b990254cb9
https://doi.org/10.1016/0264-410x(95)00221-l

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Plasmodium falciparum Incidence Relative to Entomologic Inoculation Rates at a Site Proposed for Testing Malaria Vaccines in Western Kenya

Autor: Charles N. Oster, James A. Sherwood, Peter V. Perkins, Carter L. Diggs, Fred K. Onyango, James D. Bales, John C. Beier, David K. Chumo, Richard E. Whitmire, Stephen L. Hoffman, Davy V. Koech, Clifford R. Roberts

Publikováno v: The American Journal of Tropical Medicine and Hygiene. 50:529-536

Relationships between Plasmodium falciparum incidence and entomologic inoculation rates (EIRs) were determined for a 21-month period in Saradidi, western Kenya, in preparation for malaria vaccine field trials. Children, ranging in age from six months

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7edb4878f2b95ef734dfd8cc5a403cd6
https://doi.org/10.4269/ajtmh.1994.50.529

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Use of pharmacological agents to implicate a role for phosphoinositide hydrolysis products in malaria gamete formation

Autor: G.S. Gachihi, Aba Nwachukwu, Clifford R. Roberts, Rose Ogwan'g, Samuel K. Martin, Josephat Mwangi

Publikováno v: Biochemical Pharmacology. 46:1601-1606

The kinetics of phosphoinositol 4,5 bisphosphate hydrolysis products in activated Plasmodium falciparum gametocytes suggests a role for inositol trisphosphate [Ins(l,4,5)P 3 ] and diacylglycerol (DAG) in the signal transduction pathway of malaria gam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99df9d2a66a17fa93a29363b1111e068
https://doi.org/10.1016/0006-2952(93)90329-u

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Identification of central Kenyan Rift Valley Fever virus vector habitats with landsat TM and evaluation of their flooding status with airborne imaging radar

Autor: Thomas M. Logan, A.R. Njogu, K.O. Pope, Charles L. Bailey, K. Birney, Kenneth J. Linthicum, Clifford R. Roberts, E.J. Sheffner, Eric S. Kasischke

Publikováno v: Remote Sensing of Environment. 40:185-196

Rift Valley Fever (RVF) is a mosquito-borne virus that affects livestock and humans in Africa. Landsat TM data are shown to be effective in identifying dambos, intermittently flooded areas that are potential mosquite breeding sites, in an area north

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https://doi.org/10.1016/0034-4257(92)90002-2

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Modular Buildings

Autor: William E. Britz, Clifford R. Roberts

Publisher Summary This chapter discusses the pros and cons of using modular building design in setting up an animal facility. Site preparation concurrent with building construction and the construction of modular buildings in a factory precludes weat

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https://doi.org/10.1016/b978-0-12-369517-8.00016-5

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