Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Clifford P. Stanners"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 2, Pp 151-163 (2002)
Human carcinoembryonic antigen (CEA) and the CEA family member CEACAM6 (formerly nonspecific crossreacting antigen [NCA]) function in vitro, at least, as homotypic intercellular adhesion molecules and, in model systems, can block the terminal differe
Externí odkaz:
https://doaj.org/article/e5bf7ecb310f4eec8862c3f35815a8f8
Autor:
Anna Sintsova, Helen Sarantis, Epshita A Islam, Chun Xiang Sun, Mohsen Amin, Carlos H F Chan, Clifford P Stanners, Michael Glogauer, Scott D Gray-Owen
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004341 (2014)
An overwhelming neutrophil-driven response causes both acute symptoms and the lasting sequelae that result from infection with Neisseria gonorrhoeae. Neutrophils undergo an aggressive opsonin-independent response to N. gonorrhoeae, driven by the inna
Externí odkaz:
https://doaj.org/article/8335597d42c142c7b244c8d87da04880
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1353 (2007)
CEA and CEACAM6 are immunoglobulin family intercellular adhesion molecules that are up-regulated without structural mutations in approximately 70% of human cancers. Results in in vitro systems showing tumorigenic effects for these molecules suggest t
Externí odkaz:
https://doaj.org/article/9d449e9a8e67414097b2df4b9805b042
Publikováno v:
Current Oncology
Volume 14
Issue 2
Pages 109-73
Volume 14
Issue 2
Pages 109-73
Richard J. Ablin, Phd, Research Professor of Immunobiology, University of Arizona College of Medicine and the Arizona Cancer Center, Tucson, Arizona, U.S.A., and Phil Gold, Phd md, Professor of Medicine, Physiology, and Oncology, McGill University, M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3b2dda1bb6bd282e8d436286b50e9d
https://doi.org/10.3747/co.2007.109
https://doi.org/10.3747/co.2007.109
Publikováno v:
Molecular Biology of the Cell. 18:1366-1374
GPI membrane anchors of cell surface glycoproteins have been shown to confer functional properties that are different from their transmembrane (TM)-anchored counterparts. For the human carcinoembryonic antigen (CEA) family, a subfamily of the immunog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c3531ee892757bf21e5e1c3bbf4462
https://doi.org/10.1091/mbc.e06-10-0884
https://doi.org/10.1091/mbc.e06-10-0884
Publikováno v:
The Journal of Cell Biology
The functional specificity conferred by glycophosphatidylinositol (GPI) anchors on certain membrane proteins may arise from their occupancy of specific membrane microdomains. We show that membrane proteins with noninteractive external domains attache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278cc19623e1d3009ff63922cdcc059d
https://doi.org/10.1083/jcb.200605001
https://doi.org/10.1083/jcb.200605001
Autor:
Pilar Camacho-Leal, Clifford P. Stanners, Mannie M.Y. Fan, Alexander B. Zhai, Luisa DeMarte, Cosme Ordonez
Publikováno v:
Journal of Cellular Physiology. 210:757-765
Carcinoembryonic antigen (CEA) and CEA family member CEACAM6 are glycophosphatidyl inositol (GPI)-anchored, intercellular adhesion molecules that are up-regulated in a wide variety of human cancers, including colon, breast, and lung. When over-expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d313ff5841834f38f8d5eed53125e3
https://doi.org/10.1002/jcp.20887
https://doi.org/10.1002/jcp.20887
Publikováno v:
Molecular Therapy. 9:775-785
Many novel cancer therapies, including immunotherapy and gene therapy, are specifically targeted to tumor-associated molecules, among which carcinoembryonic antigen (CEA) represents a popular example. Discrepancies between preclinical experimental da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0850c1605587d15f7366eb359e2869ef
https://doi.org/10.1016/j.ymthe.2004.03.009
https://doi.org/10.1016/j.ymthe.2004.03.009
Publikováno v:
Cancer Gene Therapy. 11:297-306
Chimeric immunoglobulin-T-cell receptor (IgTCR)-modified T cells ("designer T cells") kill tumor cells based on antibody-redirected recognition of tumor-associated antigen. Anti-carcinoembryonic antigen (CEA) designer T cells have been prepared and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd07bfb89aff373f9f2bcbab5178209
https://doi.org/10.1038/sj.cgt.7700685
https://doi.org/10.1038/sj.cgt.7700685