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pro vyhledávání: '"Cleophas TJ"'
Autor:
Cleophas Tj
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 43:23-29
Background: Data modeling can be applied to improving the precision of clinical studies and multiple regression modeling is increasingly used for this purpose. Objective: To assess the uncertainties and risks of misinterpretations commonly encountere
Autor:
Zwinderman Ah, Cleophas Tj
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 39:383-388
BACKGROUND Four large double-blind placebo-controlled studies have been performed to address mortality as a primary endpoint in patients with heart failure treated with beta-blockers. Unfortunately, 2 of the studies were stopped in the interim stage,
Autor:
Cleophas Tj, Kalmansohn Rb
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 38:373-380
Background: We recently demonstrated that in self-controlled clinical trials using t-statistic the correlation level between treatment responses is an important determinant of the sensitivity of testing. Methods: The current study uses hypothetical e
Autor:
A H Zwinderman, Cleophas Tj
Publikováno v:
International journal of clinical pharmacology and therapeutics. 46(8)
Background In clinical trials a fixed effects research model assumes that the patients selected for a specific treatment have the same true quantitative effect and that the differences observed are residual error. If, however, we have reasons to beli
Autor:
Zwinderman Ah, Cleophas Tj
Publikováno v:
International journal of clinical pharmacology and therapeutics. 43(11)
Background: Clinical investigators, although they are generally familiar with testing differences between averages, have difficulty testing differences between variabilities. Objective: To give examples of situations where variability is more relevan
Autor:
Cleophas, GCJM, Cleophas, TJ
Publikováno v:
International Journal of Clinical Pharmacology and Therapeutics, 41(2), 51-55. Dustri-Verlag Dr. Karl Feistle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::d996bcfdc5eb3f6dd0bdb3ccc95e986a
https://pure.eur.nl/en/publications/aec35d09-6ee8-4158-91c8-c813a89530e7
https://pure.eur.nl/en/publications/aec35d09-6ee8-4158-91c8-c813a89530e7
Autor:
Cleophas Tj
Publikováno v:
International journal of clinical pharmacology and therapeutics. 39(4)
Autor:
Cleophas Tj
Publikováno v:
Statistics in Medicine. 10:489-491
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