Výsledky vyhledávání - "Cleonice A.M. Bento"

Neuromyelitis optica is an HLA associated disease different from Multiple Sclerosis: a systematic review with meta-analysis

Autor: Oscar Fernandez, Laura Leyva-Fernández, Claudia Cristina Ferreira Vasconcelos, Marina Papais Alvarenga, Regina Maria Papais-Alvarenga, Helcio Alvarenga-Filho, Cleonice A.M. Bento, Marcos Papais Alvarenga, Carmen Lucia Antão Paiva, Luciana Ferreira do Carmo

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports

Neuromyelitis Optica and Multiple Sclerosis are idiopathic inflammatory demyelinating diseases of the central nervous system that currently are considered distinct autoimmune diseases, so differences in genetic susceptibility would be expected. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0957dd37b19b0668e9390330937b93
https://doaj.org/article/780a5ddcc22b4e3ea7650035a82f2f45

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Phenotypic analysis of T follicular helper and T follicular regulatory cells in primary selective IgM deficiency

Autor: Sudhir Gupta, Cleonice A.M. Bento, Taissa M. Kasahara

Publikováno v: Human Immunology. 81:625-633

Selective IgM deficiency (SIgMD) is a rare immunodeficiency characterized by serum IgM below two standard of mean, and normal IgG and IgA levels. Both in human and mice with selective IgM deficiency, germinal centers cells are decreased. The developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0ecc25307b2b61c064c1d48ade9470
https://doi.org/10.1016/j.humimm.2020.07.008

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Serum leptin levels correlate negatively with the capacity of vitamin D to modulate the in vitro cytokines production by CD4+ T cells in asthmatic patients

Autor: Cleonice A.M. Bento, Letícia Delphim, Ulisses C. Linhares, Marcos Octávio S D Cafasso, Regis M. Andrade, Sonia Regina da Silva, Anshu Agrawal, Ana Lúcia Maranhão, Isabelle C.L. Santos, Gabriel Fernandes, Larissa R. Endlich, Aleida S.O. Dias

Publikováno v: Clinical Immunology. 205:93-105

Both obesity and low vitamin D levels have been associated with allergic asthma (AA) severity. In the present study, severity of AA was associated with obesity but to the in vitro IgE production. In those patients, higher levels of IL-5, IL-6 and IL-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06342206cb93ca9c1e454a27bb0e9208
https://doi.org/10.1016/j.clim.2019.06.001

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The expansion of circulating IL-6 and IL-17-secreting follicular helper T cells is associated with neurological disabilities in neuromyelitis optica spectrum disorders

Autor: Clarice Monteiro, Aleida S.O. Dias, Alice M.M. Ornelas, Taissa M. Kasahara, Renato S. Aguiar, Ana Carolina Ribeiro de Araújo e Araújo, Cleonice A.M. Bento, Regina Maria Papais Alvarenga, Gabriel Fernandes, Priscila O. Barros

Publikováno v: Journal of Neuroimmunology. 330:12-18

Due to their function in assisting B cells, TFH cells may be involved in the production of pathogenic IgG in neuromyelitis optica spectrum disorder (NMOSD). In the present study, the proportion of IL-6+ and IL-17+ TFH cell subsets was higher in NMOSD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f9d18981e7f40c830313dfdc12e429
https://doi.org/10.1016/j.jneuroim.2019.01.015

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Major Depressive Disorder Enhances Th2 and Th17 Cytokines in Patients Suffering from Allergic Rhinitis and Asthma

Autor: Marisa C Sales, Hugo A A Oyamada, Marcos Octávio S D Cafasso, Fabianna Alvim, Camilla Castro, Priscila M. Sacramento, Ulisses C. Linhares, Carolina M Vollmer, Taissa M. Kasahara, Cleonice A.M. Bento, Lana M. Ferreira Lopes

Publikováno v: International archives of allergy and immunology. 182(12)

Introduction: Major depressive disorder (MDD) can impact the severity of allergic rhinitis (AR) and asthma (AA). Here, we evaluated the cytokine production by T-cells from AR and AA patients with or without MDD. The effect of serotonin on the in vitr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19a7f04d29f9dc6a678c82cc1feff0a
https://pubmed.ncbi.nlm.nih.gov/34348317

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Phenotypic and Functional Analysis of T Follicular Cells in Common Variable Immunodeficiency

Autor: Taissa de Matos Kasahara, Sudhir Gupta, Cleonice A.M. Bento

Publikováno v: International archives of allergy and immunology. 181(8)

Introduction: One of the most frequent abnormalities of B cells in common variable immunodeficiency (CVID) is reduced number of class-switched memory B cells, suggesting an impaired germinal center response. Therefore, due to its pivotal role in regu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a600d12d1955eb9a8a9e98bc90fa10e
https://pubmed.ncbi.nlm.nih.gov/32492690

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Serotonin decreases the production of Th1/Th17 cytokines and elevates the frequency of regulatory CD4+T-cell subsets in multiple sclerosis patients

Autor: Marisa C Sales, Cleonice A.M. Bento, Fernanda Rueda, Thais B. Ferreira, Taissa M. Kasahara, Regis M. Andrade, Ana Cristina Wing, Clarice Monteiro, Claudia Cristina Ferreira Vasconcelos, Aleida S.O. Dias, Joana Hygino, Priscila M. Sacramento

Publikováno v: European Journal of Immunology. 48:1376-1388

Excessive levels of proinflammatory cytokines in the CNS are associated with reduced serotonin (5-HT) synthesis, a neurotransmitter with diverse immune effects. In this study, we evaluated the ability of exogenous 5-HT to modulate the T-cell behavior

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b9bc4ae6b0dc077a42c5bfc0efc492c
https://doi.org/10.1002/eji.201847525

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Different interleukin-17-secreting Toll-like receptor+ T-cell subsets are associated with disease activity in multiple sclerosis

Autor: Anshu Agrawal, Sudhir Gupta, Regina Maria Papais Alvarenga, Soniza Vieira Alves-Leon, Claudia Cristina Ferreira Vasconcelos, Joana Hygino, Ana Cristina Wing, Cleonice A.M. Bento, Taissa M. Kasahara, Fernanda Rueda, Priscila M. Sacramento, Thais B. Ferreira, Solange Camargo

Publikováno v: Immunology. 154:239-252

Signalling through Toll-like receptors (TLRs) may play a role in the pathogenesis of autoimmune diseases, such as multiple sclerosis (MS). In the present study, the expression of TLR-2, -4 and -9 was significantly higher on CD4+ and CD8+ T-cells from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94f41743b5bf19e9f50dc2f0a5c4f7ec
https://doi.org/10.1111/imm.12872

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Pregnancy favors the expansion of circulating functional follicular helper T Cells

Autor: Taissa M. Kasahara, Vander G. Silva, Priscila M. Sacramento, Clarice Monteiro, Sudhir Gupta, Lana M. Ferreira Lopes, Tatiane Cassano, Cleonice A.M. Bento, José Roberto Castro, Joana Hygino, Newton Centurião, Simone Leite

Publikováno v: Journal of Reproductive Immunology. 121:1-10

Pregnancy favors antibody production, and some evidence has suggested a direct effect of estrogen on B cells. The impact of pregnancy on circulating follicular helper T (TFH) cells, typically identified by the expression of CD45RO and CXCR5, has not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1065211312fa11dbb944e11cc88318cf
https://doi.org/10.1016/j.jri.2017.04.007

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