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of 3
pro vyhledávání: '"Cleo Selina Bonnet"'
Autor:
Sophie J. Gilbert, Ryan Jones, Ben J. Egan, Cleo Selina Bonnet, Sam L. Evans, Deborah J. Mason
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionChanges to bone physiology play a central role in the development of osteoarthritis with the mechanosensing osteocyte releasing factors that drive disease progression. This study developed a humanised in vitro model to detect osteocyte re
Externí odkaz:
https://doaj.org/article/60634a5c91fd4126a4250923903c1936
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13595 (2021)
The composition and organisation of the extracellular matrix (ECM), particularly the pericellular matrix (PCM), in articular cartilage is critical to its biomechanical functionality; the presence of proteoglycans such as aggrecan, entrapped within a
Externí odkaz:
https://doaj.org/article/45698ae0e56f470b9601e527f16d8eb4
Autor:
Sophie eGilbert, Lee eMeakin, Cleo Selina Bonnet, Mari eNowell, Warren eLadiges, John eMorton, Victor eDuance, Deborah eMason
Publikováno v:
Frontiers in Endocrinology, Vol 5 (2014)
Objective. Protein kinase-like endoplasmic reticulum kinase (PERK) and protein kinase R (PKR) are implicated in endoplasmic reticulum stress-induced arthritis and pro-inflammatory cytokine-mediated cartilage degradation in vitro, respectively. We det
Externí odkaz:
https://doaj.org/article/60c5a01e765848d3a0ab73cc38c1e2c0