Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cleo Bonnet"'
Publikováno v:
JCI Insight
Musculoskeletal disorders represent the third greatest burden in terms of death and disability in the developed world. Osteoarthritis is the single greatest cause of chronic pain, has no cure, and affects 8.5 and 27 million people in the UK and US, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4975fd5dfb6c3c74b93aceac10e09ac2
https://orca.cardiff.ac.uk/id/eprint/132682/2/134055.2-20200707154633-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf
https://orca.cardiff.ac.uk/id/eprint/132682/2/134055.2-20200707154633-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf
Publikováno v:
Osteoarthritis and Cartilage. 28:S490-S491
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97cb0a4e3fe581e635f07b832f849aa6
https://doi.org/10.1016/j.joca.2020.02.767
https://doi.org/10.1016/j.joca.2020.02.767
Publikováno v:
Publons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40621926138fde7ce00bfcd22d18fc1
https://doi.org/10.1016/j.joca.2020.02.295
https://doi.org/10.1016/j.joca.2020.02.295
Publikováno v:
Osteoarthritis and Cartilage. 27:S170-S171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da8929afe1b79521c898064cf7aa9063
https://doi.org/10.1016/j.joca.2019.02.255
https://doi.org/10.1016/j.joca.2019.02.255
Autor:
Paul Biggs, Karen Sarah Brakspear, Catherine Avril Holt, Catherine Wilson, Carole Elford, Deborah Jane Mason, Cleo Bonnet, Gemma Marie Whatling
Publikováno v:
Osteoarthritis and Cartilage. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae566ee781d66b3856f180cff84727ea
Autor:
Mark Aldred, Christopher John Von Ruhland, Jeremy Peter Cheadle, Richard Sandford, Cleo Bonnet, Rebecca Harris
Publikováno v:
Human Molecular Genetics. 18:2166-2176
Clinical trials are underway for the treatment of tuberous sclerosis (TSC)-associated tumours using mTOR inhibitors. Here, we show that many of the earliest renal lesions from Tsc1+/- and Tsc2+/- mice do not exhibit mTOR activation, suggesting that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5670916e7a8fbeafd22e0f5ca110506c
https://doi.org/10.1093/hmg/ddp149
https://doi.org/10.1093/hmg/ddp149
Autor:
Bronwen Alice James Evans, Ann K Harvey, Deborah Jane Mason, Cleo Bonnet, Sophie Jane Gilbert, Anwen Sian Williams
Publikováno v:
Annals of the Rheumatic Diseases
ObjectivesSynovial fluid glutamate concentrations increase in arthritis. Activation of kainate (KA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors (GluRs) increase interleukin-6 (IL-6) release and cause arthritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c593ab6c3d8aeefe8b63ee5d212d9cee
Autor:
Vic Duance, Sophie Jane Gilbert, Warren Ladiges, Mari Ann Nowell, John Morton, Deborah Jane Mason, Cleo Bonnet
Publikováno v:
Bone Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b255f17855cd4ea17f534789cff819c
https://doi.org/10.1530/boneabs.1.pp29
https://doi.org/10.1530/boneabs.1.pp29
Autor:
Bronwen Alice James Evans, Anwen Sian Williams, Sophie Jane Gilbert, Ann K Harvey, Deborah Jane Mason, Cleo Bonnet
Publikováno v:
Bone Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c407b1d0e006ab23c2acb32cbca3804a
https://doi.org/10.1530/boneabs.1.pp28
https://doi.org/10.1530/boneabs.1.pp28
Autor:
Cleo Bonnet, Carol Guy, Jeremy Peter Cheadle, Julie Helen Maynard, Julian R. Sampson, Shelley Idziaszczyk, James Colley, Catherine H. Wilson, Vikki Humphreys
Publikováno v:
Cancer research. 66(16)
Tuberous sclerosis complex (TSC) is caused by mutations in either the TSC1 or TSC2 gene. Both genes are generally considered to act as tumor suppressors that fulfill Knudson's “two-hit hypothesis” and that function within the phosphoinositide 3-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e09396cb7ffadd7f0cf08c41bc6476f
https://pubmed.ncbi.nlm.nih.gov/16912167
https://pubmed.ncbi.nlm.nih.gov/16912167