Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Clementine Nordon"'
Autor:
Emily L. Graul, Clementine Nordon, Kirsty Rhodes, Shruti Menon, Mahmoud Al Ammouri, Constantinos Kallis, Anne E. Ioannides, Hannah R. Whittaker, Nicholas S. Peters, Jennifer K. Quint
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background An immediate, temporal risk of heart failure and arrhythmias after a Chronic Obstructive Pulmonary Disease (COPD) exacerbation has been demonstrated, particularly in the first month post-exacerbation. However, the clinical profile
Externí odkaz:
https://doaj.org/article/5d521aa9554c49409c83e9d38dbcea4c
Autor:
Hana Müllerova, Clementine Nordon, Patrick Timpel, Kirsty Rhodes, Claus F Vogelmeier, Edeltraut Garbe, Melanie Abram, Marija Halbach, Nils Kossack, Nikolaus Kolb
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background Exacerbations of chronic obstructive pulmonary disease (COPD) represent a period of vulnerability. This study explored the association between time periods following an exacerbation and the risk of severe cardiovascular (CV) events or deat
Externí odkaz:
https://doaj.org/article/2058ed21aab94def965644460836c9c2
Autor:
Karin M. A. Swart, Brenda N. Baak, Louise Lemmens, Fernie J. A. Penning-van Beest, Camilla Bengtsson, Muriel Lobier, Fabian Hoti, Dina Vojinovic, Lindy van Burk, Kirsty Rhodes, Edeltraut Garbe, Ron M. C. Herings, Clementine Nordon, Sami O. Simons
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background People living with chronic obstructive pulmonary disease (COPD) have an increased risk of experiencing cardiovascular (CV) events, particularly after an exacerbation. Such CV burden is not yet known for incident COPD patients. We
Externí odkaz:
https://doaj.org/article/b7f1bda75ac343adbd4dcaa1bfb633cd
Autor:
Clementine Nordon, Benoit Sanchez, Mei Zhang, Xiaowei Wang, Phillip Hunt, Mark Belger, Helene Karcher
Publikováno v:
Contemporary Clinical Trials Communications, Vol 33, Iss , Pp 101142- (2023)
Background: Exclusion criteria that are treatment effect modifiers (TEM) decrease RCTs results generalisability and the potentials of effectiveness estimation. In “augmented RCTs”, a small proportion of otherwise-excluded patients are included to
Externí odkaz:
https://doaj.org/article/cc82de7d21324183b203cdb3c23368dd
Autor:
Jennifer K Quint, Hana Müllerova, Clementine Nordon, Nathaniel M Hawkins, Jonathan Marshall, Sami O Simons, Kirsty Rhodes, Claus F Vogelmeier, Mario Ouwens, Edeltraut Garbe
Publikováno v:
BMJ Open, Vol 13, Iss 4 (2023)
Introduction In patients with chronic obstructive pulmonary disease (COPD), the risk of certain cardiovascular (CV) events is increased by threefold to fivefold in the year following acute exacerbation of COPD (AECOPD), compared with a non-exacerbati
Externí odkaz:
https://doaj.org/article/3a655a09a54045f5bc0daaeae73be741
Autor:
Hana Müllerová, Jonathan Marshall, Enrico de Nigris, Precil Varghese, Nick Pooley, Nina Embleton, Clementine Nordon, Zoe Marjenberg
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 16 (2022)
Background: The majority of patients with chronic obstructive pulmonary disease (COPD) suffer from comorbid cardiovascular (CV) disease. Accumulating evidence suggests a temporal association between COPD exacerbations and acute CV events, possibly du
Externí odkaz:
https://doaj.org/article/61b8a741bae540a9b18f84f2f0c2dfac
Autor:
Lamiae Grimaldi-Bensouda, Bernard Begaud, Jacques Benichou, Clementine Nordon, Olivia Dialla, Nicolas Morisot, Yann Hamon, Yves Cottin, Elie Serrano, Lucien Abenhaim, Emmanuel Touzé
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Pharmacovigilance reports of cerebral and cardiovascular events in those who use decongestants have triggered alerts related to their use. We aimed to assess the risk of stroke and myocardial infarction (MI) associated with the use of decong
Externí odkaz:
https://doaj.org/article/df2016a659954236b767621939ce8ec0
The 'RCT augmentation': a novel simulation method to add patient heterogeneity into phase III trials
Autor:
Helene Karcher, Shuai Fu, Jie Meng, Mikkel Zöllner Ankarfeldt, Orestis Efthimiou, Mark Belger, Josep Maria Haro, Lucien Abenhaim, Clementine Nordon, on behalf of the GetReal Consortium Work Package
Publikováno v:
BMC Medical Research Methodology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background Phase III randomized controlled trials (RCT) typically exclude certain patient subgroups, thereby potentially jeopardizing estimation of a drug’s effects when prescribed to wider populations and under routine care (“effectiven
Externí odkaz:
https://doaj.org/article/476787d5e1b34f6b872ca637c030a6cc
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77757 (2013)
BACKGROUND: Anorexia nervosa is a severe psychiatric disorder mainly affecting women. Its treatment is long and accepted with much difficulty, in particular in-patient treatment. AIMS: To describe the subjective motives of women with anorexia nervosa
Externí odkaz:
https://doaj.org/article/e4bcf1414479407faecaaa88948fa98b
Autor:
Bo Ding, Rebecca Zaha, Naoyuki Makita, Sophie Graham, Dimitra Lambrelli, Samuel Huse, Hana Müllerová, Clementine Nordon, Shigeo Muro
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease. 18:247-258
Bo Ding,1 Rebecca Zaha,2 Naoyuki Makita,3 Sophie Graham,4,5 Dimitra Lambrelli,4 Samuel Huse,6 Hana Müllerová,7 Clementine Nordon,7 Shigeo Muro8 1BioPharmaceuticals Medical, AstraZeneca, Gothenburg, Sweden; 2Formerly of Data Analytics, Evidera,