Výsledky vyhledávání - "Clementine Hofmann"

Akademický článek

Cannabinoid type-1 receptor signaling in dopaminergic Engrailed-1 expressing neurons modulates motivation and depressive-like behavior

Autor: Sarah Baddenhausen, Beat Lutz, Clementine Hofmann

Publikováno v: Frontiers in Molecular Neuroscience, Vol 17 (2024)

The endocannabinoid system comprises highly versatile signaling functions within the nervous system. It is reported to modulate the release of several neurotransmitters, consequently affecting the activity of neuronal circuits. Investigations have hi

Externí odkaz: https://doaj.org/article/92230dc93f38410aa7ae1963d141e289

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Akademický článek

A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction

Autor: Laura Domingo-Rodriguez, Inigo Ruiz de Azua, Eduardo Dominguez, Eric Senabre, Irene Serra, Sami Kummer, Mohit Navandar, Sarah Baddenhausen, Clementine Hofmann, Raul Andero, Susanne Gerber, Marta Navarrete, Mara Dierssen, Beat Lutz, Elena Martín-García, Rafael Maldonado

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Food addiction is linked to obesity and eating disorders. In a mouse model of food addiction, the authors show that a medial prefrontal cortex-nucleus accumbens pathway is involved in vulnerability and resilience against the development of food addic

Externí odkaz: https://doaj.org/article/c8dbd884c89140e9a18f63fc4ca8779d

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Akademický článek

A moderate diet restriction during pregnancy alters the levels of endocannabinoids and endocannabinoid-related lipids in the hypothalamus, hippocampus and olfactory bulb of rat offspring in a sex-specific manner.

Autor: María Teresa Ramírez-López, Mariam Vázquez, Ermelinda Lomazzo, Clementine Hofmann, Rosario Noemi Blanco, Francisco Alén, María Antón, Juan Decara, Rocío Arco, Laura Orio, Juan Suárez, Beat Lutz, Raquel Gómez de Heras, Laura Bindila, Fernando Rodríguez de Fonseca

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0174307 (2017)

Undernutrition during pregnancy has been associated to increased vulnerability to develop metabolic and behavior alterations later in life. The endocannabinoid system might play an important role in these processes. Therefore, we investigated the eff

Externí odkaz: https://doaj.org/article/8e6e19443866443eb11592648bded30b

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Akademický článek

Maternal caloric restriction implemented during the preconceptional and pregnancy period alters hypothalamic and hippocampal endocannabinoid levels at birth and induces overweight and increased adiposity at adulthood in male rat offspring

Autor: MARÍA TERESA RAMÍREZ-LÓPEZ, Mariam Vazquez, Laura Bindila, Ermelinda Lomazzo, Clementine Hofmann, Noemi Blanco, Francisco Alen, MARIA ANTÓN, Juan Decara, Rocío Arco, Daniel Ouro, LAURA ORIO, JUAN SUAREZ, Beat Lutz, Raquel Gomez de Heras, FERNANDO RODRIGUEZ DE FONSECA

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 10 (2016)

Exposure to inadequate nutritional conditions in critical windows of development has been associated to disturbances on metabolism and behavior in the offspring later in life. The role of the endocannabinoid system, a known regulator of energy expend

Externí odkaz: https://doaj.org/article/6b49d00fc8794584855728b968b01db1

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A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction

Autor: Elena Martín-García, Sarah Baddenhausen, Susanne Gerber, Clementine Hofmann, Eric Senabre, Eduardo Domínguez, Irene Serra, Raül Andero, Inigo Ruiz de Azua, Laura Domingo-Rodriguez, Sami Kummer, Rafael Maldonado, Marta Navarrete, Mohit Navandar, Beat Lutz, Mara Dierssen

Publikováno v: Nature Communications, 11(1):782
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
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Food addiction is linked to obesity and eating disorders and is characterized by a loss of behavioral control and compulsive food intake. Here, using a food addiction mouse model, we report that the lack of cannabinoid type-1 receptor in dorsal telen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5b0ca21e6ec730893a6c612286e8ad
https://repository.publisso.de/resource/frl:6422242

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Exposure to a Highly Caloric Palatable Diet During Pregestational and Gestational Periods Affects Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Adiposity and Anxiety-Like Behaviors in Male Rat Offspring

Autor: Juan Decara, Ermelinda Lomazzo, Laura Bindila, Laura Orio, Clementine Hofmann, Daniel Ouro, Rosario Noemi Blanco, Juan Suárez, Francisco Alén, María Teresa Ramírez-López, Fernando Rodríguez de Fonseca, Raquel Gómez de Heras, Beat Lutz, María Antón, Mariam Vázquez

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 9 (2016)
Frontiers in Behavioral Neuroscience

Journal Article; Exposure to unbalanced diets during pre-gestational and gestational periods may result in long-term alterations in metabolism and behavior. The contribution of the endocannabinoid system to these long-term adaptive responses is unkno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cd7965bd4b0fffcea93ff85fa1a67b
https://doi.org/10.3389/fnbeh.2015.00339

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The CB1Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis

Autor: Hui-Chen Lu, Chia Shan Wu, Patricia P. Garcez, Clementine Hofmann, Ismael Galve-Roperh, François Guillemot, Javier Palazuelos, Manuel Guzmán, Javier Díaz-Alonso, Beat Lutz, Tania Aguado

Publikováno v: The Journal of Neuroscience. 32:16651-16665

The generation and specification of pyramidal neuron subpopulations during development relies on a complex network of transcription factors. The CB1cannabinoid receptor is the major molecular target of endocannabinoids and marijuana active compounds.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bd5eac85d0cff7cb5d1b2062559973
https://doi.org/10.1523/jneurosci.0681-12.2012

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Perivascular cells expressing annexin A5 define a novel mesenchymal stem cell-like population with the capacity to differentiate into multiple mesenchymal lineages

Autor: Friederike Pausch, Thomas Winkler, Bent Brachvogel, Ernst Pöschl, Rupert Hallmann, Klaus von der Mark, Ursula Schlötzer-Schrehardt, Clementine Hofmann, Helga Moch

Publikováno v: Development. 132:2657-2668

The annexin A5 gene ( Anxa5 ) was recently found to be expressed in the developing and adult vascular system as well as the skeletal system. In this paper, the expression of an Anxa5 - lacZ fusion gene was used to define the onset of expression in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741e2721599b6577d24785ff9b84c4f9
https://doi.org/10.1242/dev.01846

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Generation of a conditional allele of theCBPgene in mouse

Autor: Günther Schütz, Emilio Casanova, Clementine Hofmann, Beat Lutz, Zuwen Zhang

Publikováno v: genesis. 40:82-89

CREB-binding protein (CBP) is an important transcriptional cofactor for various intracellular signaling pathways, including Ca(2+)- and cAMP-mediated gene activation. The loss of one CBP allele causes the human Rubinstein-Taybi syndrome, which is cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::486c6795da6a2363f86c1a86bd4299b1
https://doi.org/10.1002/gene.20068

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