Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Clementina A Mesaros"'
Autor:
Prasanna M Chandramouleeswaran, Manti Guha, Masataka Shimonosono, Kelly A Whelan, Hisatsugu Maekawa, Uma M Sachdeva, Gordon Ruthel, Sarmistha Mukherjee, Noah Engel, Michael V Gonzalez, James Garifallou, Shinya Ohashi, Andres J Klein-Szanto, Clementina A Mesaros, Ian A Blair, Renata Pellegrino da Silva, Hakon Hakonarson, Eishi Noguchi, Joseph A Baur, Hiroshi Nakagawa
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239625 (2020)
During alcohol consumption, the esophageal mucosa is directly exposed to high concentrations of ethanol (EtOH). We therefore investigated the response of normal human esophageal epithelial cell lines EPC1, EPC2 and EPC3 to acute EtOH exposure. While
Externí odkaz:
https://doaj.org/article/5a4df4b8798b4fd795ef2f8d80b295c8
Autor:
Yee Hoon Foong, Blake Caldwell, Joanne L. Thorvaldsen, Christopher Krapp, Clementina A. Mesaros, Wanding Zhou, Rahul M. Kohli, Marisa S. Bartolomei
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
TET1/2/3 dioxygenases iteratively demethylate 5-methylcytosine, beginning with the formation of 5-hydroxymethylcytosine (5hmC). The post-mitotic brain maintains higher levels of 5hmC than most peripheral tissues, and TET1 ablation studies have unders
Externí odkaz:
https://doaj.org/article/15da1f095f5e460fb87e5885ecd73cc9
Autor:
Eleonora Scorletti, Yedidya Saiman, Sookyoung Jeon, Carolin V. Schneider, Delfin G. Buyco, Chelsea Lin, Blanca E. Himes, Clementina A. Mesaros, Marijana Vujkovic, Kate Townsend Creasy, Emma E. Furth, Jeffrey T. Billheimer, Nicholas J. Hand, David E. Kaplan, Kyong-Mi Chang, Philip S. Tsao, Julie A. Lynch, Joseph L. Dempsey, Julia Harkin, Susovon Bayen, Donna Conlon, Marie Guerraty, Michael C. Phillips, Daniel J. Rader, Rotonya M. Carr
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100902- (2024)
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is characterised by the accumulation of lipid droplets (LDs) within hepatocytes. Perilipin 2 (PLIN2) is the most abundant protein in hepatic LDs and its expression correlates with intracell
Externí odkaz:
https://doaj.org/article/0f2aac76aa174d06be32dcaf8efba46a
Autor:
Jason Garcia, Kirsten D. Krieger, Candice Loitz, Lillian M. Perez, Zachary A. Richards, Yves Helou, Steve Kregel, Sasha Celada, Clementina A. Mesaros, Maarten Bosland, Peter H. Gann, Thomas E. Willnow, Donald Vander Griend, Rick Kittles, Gail S. Prins, Trevor Penning, Larisa Nonn
Publikováno v:
Cancer Research Communications. 3:371-382
Vitamin D deficiency is associated with an increased risk of prostate cancer mortality and is hypothesized to contribute to prostate cancer aggressiveness and disparities in African American populations. The prostate epithelium was recently shown to
Publikováno v:
Chemical Research in Toxicology. 35:2296-2309
1-Nitropyrene (1-NP) and 1,8-dinitropyrene (1,8-DNP) are diesel exhaust constituents and are classified by the International Agency for Research on Cancer as probable (Group 2A) or possible (Group 2B) human carcinogens. These nitroarenes undergo meta
Autor:
Larisa Nonn, Trevor Penning, Gail S. Prins, Rick Kittles, Donald Vander Griend, Thomas E. Willnow, Peter H. Gann, Maarten Bosland, Clementina A. Mesaros, Sasha Celada, Steve Kregel, Yves Helou, Zachary A. Richards, Lillian M. Perez, Candice Loitz, Kirsten D. Krieger, Jason Garcia
Vitamin D deficiency is associated with an increased risk of prostate cancer mortality and is hypothesized to contribute to prostate cancer aggressiveness and disparities in African American populations. The prostate epithelium was recently shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0120df72475966c88157d3637f39a1
https://doi.org/10.1158/2767-9764.c.6551117
https://doi.org/10.1158/2767-9764.c.6551117
Autor:
Larisa Nonn, Trevor Penning, Gail S. Prins, Rick Kittles, Donald Vander Griend, Thomas E. Willnow, Peter H. Gann, Maarten Bosland, Clementina A. Mesaros, Sasha Celada, Steve Kregel, Yves Helou, Zachary A. Richards, Lillian M. Perez, Candice Loitz, Kirsten D. Krieger, Jason Garcia
S1. Accompanies Figure 1 and 2.S2. Accompanies Figure 2. No differences in bitransgenic mouse prostate histology, weights and fertility.S3. Relates to Figure 3. Vitamin D receptor and androgen receptor response elements in LRP2 promoter.S4. Relates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49136df2043aaef082e356eb18196eb2
https://doi.org/10.1158/2767-9764.22546184
https://doi.org/10.1158/2767-9764.22546184
Publikováno v:
Endocrinology
Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women. A common symptom of PCOS is hyperandrogenism (AE); however, the source of these androgens is uncertain. Aldo-keto reductase family 1 member C3 (AKR1C3) catalyzes the form
Autor:
Yuka Sakata, Keren Cheng, Michinori Mayama, Yasunari Seita, Andrea J. Detlefsen, Clementina A. Mesaros, Trevor M. Penning, Kyosuke Shishikura, Wenli Yang, Richard J. Auchus, Jerome F. Strauss, Kotaro Sasaki
Publikováno v:
Dev Cell
The mechanisms leading to adrenal cortex development and steroid synthesis in humans remain poorly understood due to the paucity of model systems. Herein, we faithfully recapitulate human fetal adrenal cortex specification processes through stepwise
Autor:
Kathleen O’Neill, Jacqueline Alexander, Rikka Azuma, Rui Xiao, Nathaniel W. Snyder, Clementina A. Mesaros, Ian A. Blair, Sara E. Pinney
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2696 (2018)
Maternal diabetes and obesity induce marked abnormalities in glucose homeostasis and insulin secretion in the fetus, and are linked to obesity, diabetes, and metabolic disease in the offspring, with specific metabolic characterization based on offspr
Externí odkaz:
https://doaj.org/article/a9d7f6c69c184f3d82479073bbeeb5ef