Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clement Yau"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Interleukin-7 (IL-7) is a cytokine known for its importance in T cell development and survival. How IL-7 shapes CD8 T cell responses during an acute viral infection is less understood. We had previously shown that IL-7 signaling deficient mi
Externí odkaz:
https://doaj.org/article/40004d580a92456d980acf42484e3609
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101297- (2022)
Summary: Aberrant cellular bioenergetics has detrimental consequences in host cells. For instance, pathogenic Zika virus strains can suppress mitochondria respiration and glycolytic functions, disrupting cellular bioenergetics that leads to apoptosis
Externí odkaz:
https://doaj.org/article/23b60498dae54c3da1ab9f474195b662
Autor:
Clement Yau, John Z.H. Low, Esther S. Gan, Swee Sen Kwek, Liang Cui, Hwee Cheng Tan, Darren Z.L. Mok, Candice Y.Y. Chan, October M. Sessions, Satoru Watanabe, Subhash G. Vasudevan, Yie Hou Lee, Kuan Rong Chan, Eng Eong Ooi
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110118- (2021)
Summary: Zika virus (ZIKV) is an Aedes-mosquito-borne flavivirus that causes debilitating congenital and developmental disorders. Improved understanding of ZIKV pathogenesis could assist efforts to fill the therapeutic and vaccine gap. We use several
Externí odkaz:
https://doaj.org/article/c9c9770ca3924e2aab660c35a83c87ce
Autor:
Clement Yau, Esther Shuyi Gan, Swee Sen Kwek, Hwee Cheng Tan, Eugenia Z. Ong, Noor Zayanah Hamis, Laura Rivino, Kuan Rong Chan, Satoru Watanabe, Subhash G. Vasudevan, Eng Eong Ooi
Publikováno v:
EBioMedicine, Vol 61, Iss , Pp 103028- (2020)
Background: The emergence of Zika virus (ZIKV) as an important cause of congenital and childhood developmental disorders presents another challenge to global health. Efforts to develop a Zika vaccine have begun although vaccine development against fl
Externí odkaz:
https://doaj.org/article/1aaa19728d0f4e10a0c4451030eb9e76
Autor:
Scott C. Roberts, Hwee Cheng Tan, Sean M. Sullivan, Suezanne Parker, Daiki Matsuda, Kiyoshi Tachikawa, Rodrigo Yelin, Jerel Vega, Clement Yau, Shirin Kalimuddin, Kyoung-Joo Jenny Park, Wendy Taylor, Jenny G. Low, Ruklanthi de Alwis, Eng Eong Ooi, Hari Bhaskaran, Summer L. Zhang, Maher Alayyoubi, Yan Shan Leong, Priya Karmali, Shiwei Chen, Jared Davis, Brian M. Sullivan, Brenda Clemente, Jose A. Gonzalez, Marciano Sablad, Esther S. Gan, Elizabeth C. Allen, Paula Hartman, Steve G. Hughes, Bao Yanjie, Adrian Dukanovic, Pad Chivukula
Publikováno v:
Molecular Therapy. 29:1970-1983
A self-transcribing and replicating RNA (STARR)-based vaccine (LUNAR-COV19) has been developed to prevent SARS-CoV-2 infection. The vaccine encodes an alphavirus-based replicon and the SARS-CoV-2 full-length spike glycoprotein. Translation of the rep
Airborne diseases are the leading cause of infectious disease-related deaths in the world. In particular, the influenza virus activates a network of immune cells that leads to clearance or an overzealous response that can be fatal. Tight regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd20512f4d013e67037c64e2fde9c8c
https://doi.org/10.1101/2021.04.21.440748
https://doi.org/10.1101/2021.04.21.440748
Autor:
Satoru Watanabe, October M. Sessions, Eng Eong Ooi, Darren Mok, Hwee Cheng Tan, Yie Hou Lee, Chan Rong, John Zhong Heng Low, Clement Yau, Liang Cui, Candice Y. Chan, Subhash G. Vasudevan, Swee Sen Kwek, Esther S. Gan
Publikováno v:
SSRN Electronic Journal.
Zika virus (ZIKV) is an Aedes mosquito-borne flavivirus that causes debilitating congenital and developmental disorders. No licensed ZIKV vaccine or treatment exist, due largely to an incomplete understanding of ZIKV pathogenesis. In this study, we u
Autor:
Satoru Watanabe, Subhash G. Vasudevan, Clement Yau, Eugenia Z. Ong, Eng Eong Ooi, Laura Rivino, Noor Zayanah Hamis, Esther S. Gan, Swee Sen Kwek, Hwee Cheng Tan, Kuan Rong Chan
Publikováno v:
EBioMedicine, Vol 61, Iss, Pp 103028-(2020)
EBioMedicine
Yau, C, Gan, E S, Kwek, S S, Tan, H C, Ong, E Z, Hamis, N Z, Rivino, L, Chan, K R, Watanabe, S, Vasudevan, S G & Ooi, E E 2020, ' Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection ', EBioMedicine, vol. 61, 103028 . https://doi.org/10.1016/j.ebiom.2020.103028
EBioMedicine
Yau, C, Gan, E S, Kwek, S S, Tan, H C, Ong, E Z, Hamis, N Z, Rivino, L, Chan, K R, Watanabe, S, Vasudevan, S G & Ooi, E E 2020, ' Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection ', EBioMedicine, vol. 61, 103028 . https://doi.org/10.1016/j.ebiom.2020.103028
BACKGROUND: The emergence of Zika virus (ZIKV) as an important cause of congenital and childhood developmental disorders presents another challenge to global health. Efforts to develop a Zika vaccine have begun although vaccine development against fl
Autor:
Kiyoshi Tachikawa, Clement Yau, Jared Davis, Priya Karmali, Paula Hartman, Elizabeth Allen, Steve G. Hughes, Maher Alayyoubi, Brenda Clemente, Eng Eong Ooi, Sean M. Sullivan, Ruklanthi de Alwis, Belle Bao, Scott C. Roberts, Rodrigo Yelin, Suezanne Parker, Summer L. Zhang, Hwee Cheng Tan, Wendy Taylor, Hari Bhaskaran, Jerel Vega, Shiwei Chen, Adrian Dukanovic, Marciano Sablad, Esther S. Gan, Jenny Park, Yan Shan Leong, Daiki Matsuda, Jose A. Gonzalez, Pad Chivukula
A self-transcribing and replicating RNA (STARR™) based vaccine (LUNAR®-COV19) has been developed to prevent SARS-CoV-2 infection. The vaccine encodes an alphavirus-based replicon and the SARS-CoV-2 full length spike glycoprotein. Translation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25cdb4bf6cb0a7ab88411851fa6d2cbc
https://doi.org/10.1101/2020.09.03.280446
https://doi.org/10.1101/2020.09.03.280446
Autor:
Peter Axerio-Cilies, Paul S. Rennie, Takeshi Yamazaki, Ari Kim, Miriam S. Butler, Sam Lawn, Michael E. Cox, Yubin Guo, Fariba Ghaidi, Scott Lien, Mannan Nouri, Marta Mroczek, Lawrence P. McIntosh, Cheryl Y. Gregory-Evans, Artem Cherkasov, Martin E. Gleave, Kush Dalal, Mani Roshan-Moniri, Desmond K. W. Lau, Paul M. Yen, Michael Hsing, Clement Yau
Publikováno v:
Oncotarget
// Miriam S. Butler 1, *, # , Mani Roshan-Moniri 1, *, # , Michael Hsing 1, *, # , Desmond Lau 2, *, # , Ari Kim 1 , Paul Yen 1 , Marta Mroczek 1 , Mannan Nouri 1 , Scott Lien 1 , Peter Axerio-Cilies 1 , Kush Dalal 1 , Clement Yau 1 , Fariba Ghaidi 1