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pro vyhledávání: '"Clement W"'
Positive spanning sets (PSSs) are families of vectors that span a given linear space through non-negative linear combinations. Despite certain classes of PSSs being well understood, a complete characterization of PSSs remains elusive. In this paper,
Externí odkaz:
http://arxiv.org/abs/2411.08994
Autor:
Simone Joas, Erica H. Parrish, Clement W. Gnanadurai, Edina Lump, Christina M. Stürzel, Nicholas F. Parrish, Gerald H. Learn, Ulrike Sauermann, Berit Neumann, Kerstin Mätz Rensing, Dietmar Fuchs, James M. Billingsley, Steven E. Bosinger, Guido Silvestri, Cristian Apetrei, Nicolas Huot, Thalia Garcia-Tellez, Michaela Müller-Trutwin, Dominik Hotter, Daniel Sauter, Christiane Stahl-Hennig, Beatrice H. Hahn, Frank Kirchhoff
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
In contrast to HIV, simian immunodeficiency viruses (SIV) do not cause disease in their hosts, and the reasons for this are unclear. Here, Joas et al. incorporate two putative HIV virulence factors into SIV and study effects in infected monkeys, sugg
Externí odkaz:
https://doaj.org/article/6b840246338c48ae857ef8de0672d11d
Autor:
Goyens, Florentin, Royer, Clément W.
The difficulty of minimizing a nonconvex function is in part explained by the presence of saddle points. This slows down optimization algorithms and impacts worst-case complexity guarantees. However, many nonconvex problems of interest possess a favo
Externí odkaz:
http://arxiv.org/abs/2402.07614
Derivative-free optimization (DFO) consists in finding the best value of an objective function without relying on derivatives. To tackle such problems, one may build approximate derivatives, using for instance finite-difference estimates. One may als
Externí odkaz:
http://arxiv.org/abs/2310.00755
Autor:
Onwunta, Akwum, Royer, Clément W.
Optimization problems constrained by partial differential equations (PDEs) naturally arise in scientific computing, as those constraints often model physical systems or the simulation thereof. In an implicitly constrained approach, the constraints ar
Externí odkaz:
http://arxiv.org/abs/2309.07086
Derivative-free algorithms seek the minimum of a given function based only on function values queried at appropriate points. Although these methods are widely used in practice, their performance is known to worsen as the problem dimension increases.
Externí odkaz:
http://arxiv.org/abs/2308.04734
Positive spanning sets span a given vector space by nonnegative linear combinations of their elements. These have attracted significant attention in recent years, owing to their extensive use in derivative-free optimization. In this setting, the qual
Externí odkaz:
http://arxiv.org/abs/2306.06383
Publikováno v:
Case Reports in Ophthalmology, Vol 2, Iss 2, Pp 266-272 (2011)
During a 6-month period in 2010, 2 patients with uveitis were examined at our department and diagnosed with ocular syphilis. They initially presented with symptoms and signs resembling Harada’s disease and Behçet’s disease and were therefore tre
Externí odkaz:
https://doaj.org/article/7eb3aa0ae40344b09b9a3b8e95d7c62d
Autor:
Clement W Gnanadurai, Yang Yang, Ying Huang, Zhenguang Li, Christina M Leyson, Tanya L Cooper, Simon R Platt, Stephen B Harvey, Douglas C Hooper, Milosz Faber, Zhen F Fu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 8, p e0004023 (2015)
METHODOLOGY/PRINCIPAL FINDINGS:The experimental infection of dogs with TriGAS induced high levels of VNA in the serum, whereas wt RABV infection did not. Dogs infected with TriGAS developed antibodies against the virus including its glycoprotein, whe
Externí odkaz:
https://doaj.org/article/d57e5110474d4cc09507b32dd391ed1c
Autor:
Hare, Warren, Royer, Clément W.
Nonconvex minimization algorithms often benefit from the use of second-order information as represented by the Hessian matrix. When the Hessian at a critical point possesses negative eigenvalues, the corresponding eigenvectors can be used to search f
Externí odkaz:
http://arxiv.org/abs/2206.05318