Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Clement Regnault"'
Autor:
Nelson V. Simwela, W. Armand Guiguemde, Judith Straimer, Clement Regnault, Barbara H. Stokes, Luis E. Tavernelli, Fumiaki Yokokawa, Benjamin Taft, Thierry T. Diagana, Michael P. Barrett, Andrew P. Waters
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Characterizing the mode of action of anti-malarial compounds that emerge from high-throughput phenotypic screens is central to understanding how parasite resistance to these drugs can emerge. Here, we have employed untargeted metabolomics to
Externí odkaz:
https://doaj.org/article/5bf7e7bb83394a2cb354699274035118
Autor:
Kathryn Milne, Alasdair Ivens, Adam J Reid, Magda E Lotkowska, Aine O'Toole, Geetha Sankaranarayanan, Diana Munoz Sandoval, Wiebke Nahrendorf, Clement Regnault, Nick J Edwards, Sarah E Silk, Ruth O Payne, Angela M Minassian, Navin Venkatraman, Mandy J Sanders, Adrian VS Hill, Michael Barrett, Matthew Berriman, Simon J Draper, J Alexandra Rowe, Philip J Spence
Publikováno v:
eLife, Vol 10 (2021)
Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, ask
Externí odkaz:
https://doaj.org/article/70c326d1e81641cbb27a268a47c79208
Autor:
Marlene Jara, Michael Barrett, Ilse Maes, Clement Regnault, Hideo Imamura, Malgorzata Anna Domagalska, Jean-Claude Dujardin
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 97 (2022)
Microorganisms can adopt a quiescent physiological condition which acts as a survival strategy under unfavorable conditions. Quiescent cells are characterized by slow or non-proliferation and a deep downregulation of processes related to biosynthesis
Externí odkaz:
https://doaj.org/article/809464636c7843c9bc3abaea95591645
Autor:
Ivana Rubić, Richard Burchmore, Stefan Weidt, Clement Regnault, Josipa Kuleš, Renata Barić Rafaj, Tomislav Mašek, Anita Horvatić, Martina Crnogaj, Peter David Eckersall, Predrag Novak, Vladimir Mrljak
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1575 (2022)
Canine babesiosis is an important tick-borne disease worldwide, caused by parasites of the Babesia genus. Although the disease process primarily affects erythrocytes, it may also have multisystemic consequences. The goal of this study was to explore
Externí odkaz:
https://doaj.org/article/f5b6bf56cf104281b020124e4b4e6b7b
Autor:
Kevin M Rattigan, Andrew W Pountain, Clement Regnault, Fiona Achcar, Isabel M Vincent, Carl S Goodyear, Michael P Barrett
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194126 (2018)
Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination. In this study we have investigated the effects of pro-inflammatory and anti-inflammatory
Externí odkaz:
https://doaj.org/article/b4f18042a6cb4ffd80648fe1854f421e
Autor:
Áine Clare O'Brien, Lydia Jane Hallis, Clement Regnault, Douglas Morrison, Gavin Blackburn, Andrew Steele, Luke Daly, Alastair Tait, Marissa Marie Tremblay, Darcy E.P. Telenko, Jacqueline Gunn, Eleanor McKay, Nicola Mari, Mohammad Ali Salik, Philippa Ascough, Jaime Toney, Sammy Griffin, Phil Whitfield, Martin Lee
Publikováno v:
Astrobiology. 22:1351-1362
A key part of the search for extraterrestrial life is the detection of organic molecules since these molecules form the basis of all living things on Earth. Instrument suites such as SHERLOC (Scanning Habitable Environments with Raman and Luminescenc
Autor:
Nelson V. Simwela, W. Armand Guiguemde, Judith Straimer, Clement Regnault, Fumiaki Yokokawa, Benjamin Taft, Thierry T. Diagana, Michael P. Barrett, Andrew P. Waters
Characterizing the mode of action of antimalarial compounds that emerge from high-throughput phenotypic screens is central to understanding how parasite resistance to these drugs can emerge. Here, we have employed untargeted metabolomics to inform on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4852ff7d6867de78ef13794bc197ef3d
https://doi.org/10.1101/2022.10.03.510714
https://doi.org/10.1101/2022.10.03.510714
Autor:
Lisa Crozier, Reece Foy, Rozita Adib, Mihaly Badonyi, Ananya Kar, Jordan A. Holt, Rona Wilson, Clement Regnault, Phil Whitfield, Joseph A. Marsh, Adrian Saurin, Alexis R. Barr, Tony Ly
SUMMARYCell size and the cell cycle are intrinsically coupled and abnormal increases in cell size are associated with senescence. The mechanism by which overgrowth primes cells to exit the cell cycle remains unclear. We investigate this using CDK4/6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8f4908a9cdbc9ae91c040b33a0a8bb
https://doi.org/10.1101/2022.09.08.506843
https://doi.org/10.1101/2022.09.08.506843
Autor:
Natalia G. Apostolopoulou, Evangelia Smeti, Marta Lamorgese, Ioanna Varkitzi, Phillip Whitfield, Clement Regnault, Sofie Spatharis
Studies on microalgae interspecific interactions have so far focused either on nutrient competition or allelopathic effects due to excreted substances from Harmful Algal Bloom (HAB) species. Evidence from plants, bacteria and specific microalgae grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f6ea6fa2c137ebb1e8068fc4d75aa9
https://eprints.gla.ac.uk/265540/1/265540.pdf
https://eprints.gla.ac.uk/265540/1/265540.pdf
Autor:
Marlene Jara, Michael Barrett, Ilse Maes, Clement Regnault, Hideo Imamura, Malgorzata Anna Domagalska, Jean-Claude Dujardin
Microorganisms can adopt a quiescent physiological condition which acts as a survival strategy under unfavourable conditions. Quiescent cells are characterized by slow or non-proliferation and deep down-regulation of processes related to biosynthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79c710f6ecfd464a50da500a41a55c6
https://doi.org/10.1101/2021.12.03.470940
https://doi.org/10.1101/2021.12.03.470940