Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Clement Q, Fontenelle"'
Autor:
Emily E. Kempa, James L. Galman, Fabio Parmeggiani, James R. Marshall, Julien Malassis, Clement Q. Fontenelle, Jean-Baptiste Vendeville, Bruno Linclau, Simon J. Charnock, Sabine L. Flitsch, Nicholas J. Turner, Perdita E. Barran
Publikováno v:
JACS Au, Vol 1, Iss 4, Pp 508-516 (2021)
Externí odkaz:
https://doaj.org/article/34a43ef107ba44e88b736b23d77fadc9
Autor:
Bruno Linclau, Jean-Baptiste Vendeville, Clement Q. Fontenelle, Robert Szpera, Mark E. Light, Ramakrishna Kuppala, Edward L Briggs, David E Wheatley, Neil J. Wells
Protein-carbohydrate interactions are implicated in many biochemical/biological processes that are fundamental to life and to human health. Fluorinated carbohydrate analogues play an important role in the study of these interactions and find applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7084be9f42955cdf4ef449719b539715
https://eprints.soton.ac.uk/450092/
https://eprints.soton.ac.uk/450092/
Autor:
David E, Wheatley, Clement Q, Fontenelle, Ramakrishna, Kuppala, Robert, Szpera, Edward L, Briggs, Jean-Baptiste, Vendeville, Neil J, Wells, Mark E, Light, Bruno, Linclau
Publikováno v:
The Journal of organic chemistry. 86(11)
Protein-carbohydrate interactions are implicated in many biochemical/biological processes that are fundamental to life and to human health. Fluorinated carbohydrate analogues play an important role in the study of these interactions and find applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de605cea69bd18ea52ed43c7397e7b94
https://pubmed.ncbi.nlm.nih.gov/34029099
https://pubmed.ncbi.nlm.nih.gov/34029099
Autor:
Clement Q. Fontenelle, Emily E Kempa, Bruno Linclau, Julien Malassis, James L. Galman, Fabio Parmeggiani, Perdita E. Barran, Nicholas J. Turner, Sabine L. Flitsch, James R. Marshall, Jean-Baptiste Vendeville, Simon J. Charnock
Publikováno v:
Jacs Au
JACS Au, Vol 1, Iss 4, Pp 508-516 (2021)
JACS Au
JACS Au, Vol 1, Iss 4, Pp 508-516 (2021)
JACS Au
The lack of label-free high-throughput screening technologies presents a major bottleneck in the identification of active and selective biocatalysts, with the number of variants often exceeding the capacity of traditional analytical platforms to asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c13573f818cb2dadd4f59561747ab3
https://eprints.soton.ac.uk/450575/
https://eprints.soton.ac.uk/450575/
Autor:
Clement Q. Fontenelle, Tessa Keenan, Sabine L. Flitsch, Carl Young, Andrea Marchesi, Bruno Linclau, Alexander Peter Heyam, Martin A. Fascione, Simon J. Charnock, Wendy A. Offen, Kun Huang, Fabio Parmeggiani, Gideon J. Davies, Julien Malassis, Peter Both, Jean-Baptiste Vendeville
Summary Fluorinated sugar-1-phosphates are of emerging importance as intermediates in the chemical and biocatalytic synthesis of modified oligosaccharides, as well as probes for chemical biology. Here we present a systematic study of the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a942e049e41cbeeb5d8be3b834d14312
https://doi.org/10.26434/chemrxiv.11950647
https://doi.org/10.26434/chemrxiv.11950647
Publikováno v:
Australian Journal of Chemistry. 73:112
This is the first paper in a sequential pair devoted to the enzyme mutarotase (aldose 1-epimerase; EC 5.1.3.3). Here, the broader context of the physiological role of mutarotase, among those enzymes considered to be part of ‘metabolic structure’,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d54270bedd186364f089d6a1ae818176
https://doi.org/10.1071/ch19397
https://doi.org/10.1071/ch19397
Publikováno v:
Australian Journal of Chemistry. 73:117
Five 19F-substituted glucose analogues were used to probe the activity and mechanism of the enzyme mutarotase by using magnetisation-exchange NMR spectroscopy. The sugars (2-fluoro-2-deoxy-d-glucose, FDG2; 3-fluoro-3-deoxy-d-glucose, FDG3; 4-fluoro-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba98020a6cea33d1baba8bbcaec7ab9
https://doi.org/10.1071/ch19562
https://doi.org/10.1071/ch19562
We developed a novel approach for quantifying the equilibrium-exchange kinetics of carrier-mediated transmembrane transport of fluorinated substrates. Our method is based on an adapted kinetic theory describing the concentration dependence of the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5cdd7224f77ce838d68d3ae1edf2be
https://eprints.soton.ac.uk/425922/
https://eprints.soton.ac.uk/425922/
The regioselective protection of both methyl galactopyranoside anomers at the 2 and 3-positions as the butane diacetal (BDA) is well known. Here we describe the formation of an unexpected byproduct, which mainly occurs when α-methyl galactopyranosid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47b90ccd6dc5c620c0eb752ba6647a5
https://eprints.soton.ac.uk/415924/
https://eprints.soton.ac.uk/415924/
Autor:
Clement Q. Fontenelle, Neil J. Wells, Nicolas Galland, Bruno Linclau, Zhong Wang, Elena Bogdan, Jérôme Graton, Jean-Yves Le Questel, Florent Peron, Guillaume Compain
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Fluorination is commonly exercised in compound property optimization. However, the influence of fluorination on hydrogen-bond (HB) properties of adjacent functional groups, as well as the HB-accepting capacity of fluorine itself, is still not complet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f5482749f89c61209e30feec9134e1
https://doi.org/10.1002/chem.201503253
https://doi.org/10.1002/chem.201503253