Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clement Cocita"'
Autor:
Marija Zaric, Pablo D. Becker, Catherine Hervouet, Petya Kalcheva, Andor Doszpoly, Negin Blattman, Lauren A. O’ Neill, Barbara Ibarzo Yus, Clement Cocita, Sung-Yun Kwon, Andrew H. Baker, Graham M. Lord, Linda S. Klavinskis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Mucosal immunisation is important for initiating mucosal CD8+ Tcell responses but mucosal recruitment of protective CD8+ T cells can also be induced by skin immunisation. Here the authors examine the underlying mechanism and report a novel role for
Externí odkaz:
https://doaj.org/article/50310e1b618c4e9db13be9368bb83233
Autor:
Sam Sheppard, Iona S. Schuster, Christopher E. Andoniou, Clement Cocita, Thomas Adejumo, Sam K.P. Kung, Joseph C. Sun, Mariapia A. Degli-Esposti, Nadia Guerra
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3385-3392 (2018)
Summary: TRAIL is an apoptosis-inducing ligand constitutively expressed on liver-resident type 1 innate lymphoid cells (ILC1s) and a subset of natural killer (NK) cells, where it contributes to NK cell anti-tumor, anti-viral, and immunoregulatory fun
Externí odkaz:
https://doaj.org/article/070be39fed8543abb9f36404fb76216c
Autor:
Jey M. Jeyakumar, Azadeh Kia, Lawrence C. S. Tam, Jenny McIntosh, Justyna Spiewak, Kevin Mills, Wendy Heywood, Elisa Chisari, Noemi Castaldo, Daniël Verhoef, Paniz Hosseini, Petya Kalcheva, Clement Cocita, Carlos J. Miranda, Miriam Canavese, Jaminder Khinder, Cecilia Rosales, Derralynn Hughes, Rose Sheridan, Romuald Corbau, Amit Nathwani
Publikováno v:
Gene Therapy.
Fabry disease is an X-linked lysosomal storage disorder caused by loss of alpha-galactosidase A (α-Gal A) activity and is characterized by progressive accumulation of glycosphingolipids in multiple cells and tissues. FLT190, an investigational gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4f60e3c8e78696b3ad39b88123464b
https://doi.org/10.1038/s41434-022-00381-y
https://doi.org/10.1038/s41434-022-00381-y
Autor:
Amit C. Nathwani, Romuald Corbau, Petya Kalcheva, Emmaline Stotter, Erald Shehu, Jalpa Pandya, Fabrizio Comper, Clement Cocita, I-Mei Yu, Carlos Henrique Miranda, Natalie Northcott, Elisa Chisari, Rose Sheridan, Samantha Correia
Publikováno v:
Molecular Genetics and Metabolism. 132:S27-S28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8a97aad6f24912b4ed56ffb4911de33
https://doi.org/10.1016/j.ymgme.2020.12.047
https://doi.org/10.1016/j.ymgme.2020.12.047
Autor:
Natalie Northcott, Romuald Corbau, Ying Sun, Fabrizio Comper, Erald Shehu, Amit C. Nathwani, Rose Sheridan, Clement Cocita, Emmaline Stotter, Jalpa Pandya, I-Mei Yu, Jaminder Khinder, Petya Kalcheva, Samantha Correia, Benjamin Liou, Carlos Henrique Miranda, Elisa Chisari
Publikováno v:
Molecular Genetics and Metabolism. 132:S28-S29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aae5d07ac5b3f9fbd5e17732b5e3d979
https://doi.org/10.1016/j.ymgme.2020.12.050
https://doi.org/10.1016/j.ymgme.2020.12.050
Autor:
Prashanth K Kandalla, Julien Subburayalu, Clément Cocita, Bérengère de Laval, Elena Tomasello, Johanna Iacono, Jessica Nitsche, Maria M Canali, Wilfried Cathou, Gilles Bessou, Noushin Mossadegh‐Keller, Caroline Huber, Guy Mouchiroud, Roland P Bourette, Marie‐France Grasset, Martin Bornhäuser, Sandrine Sarrazin, Marc Dalod, Michael H Sieweke
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-20 (2023)
Abstract Therapies reconstituting autologous antiviral immunocompetence may represent an important prophylaxis and treatment for immunosuppressed individuals. Following hematopoietic cell transplantation (HCT), patients are susceptible to Herpesvirid
Externí odkaz:
https://doaj.org/article/09b31254506a4af3b59dd5b3a87d1220
Autor:
Marija, Zaric, Pablo D, Becker, Catherine, Hervouet, Petya, Kalcheva, Andor, Doszpoly, Negin, Blattman, Lauren, A O' Neill, Barbara Ibarzo, Yus, Clement, Cocita, Sung-Yun, Kwon, Andrew H, Baker, Graham M, Lord, Linda S, Klavinskis
Publikováno v:
Nature Communications
CD8+ T cells provide a critical defence from pathogens at mucosal epithelia including the female reproductive tract (FRT). Mucosal immunisation is considered essential to initiate this response, however this is difficult to reconcile with evidence th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3d4b45b2c7db605f994680871b98ead
https://pubmed.ncbi.nlm.nih.gov/31101810
https://pubmed.ncbi.nlm.nih.gov/31101810
Autor:
Sam, Sheppard, Iona S, Schuster, Christopher E, Andoniou, Clement, Cocita, Thomas, Adejumo, Sam K P, Kung, Joseph C, Sun, Mariapia A, Degli-Esposti, Nadia, Guerra
Publikováno v:
Cell Reports
Summary TRAIL is an apoptosis-inducing ligand constitutively expressed on liver-resident type 1 innate lymphoid cells (ILC1s) and a subset of natural killer (NK) cells, where it contributes to NK cell anti-tumor, anti-viral, and immunoregulatory func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ba969631cc7785e952113e2eb015e1e
https://pubmed.ncbi.nlm.nih.gov/29590608
https://pubmed.ncbi.nlm.nih.gov/29590608
Autor:
Marija, Zaric, Pablo Daniel, Becker, Catherine, Hervouet, Petya, Kalcheva, Barbara, Ibarzo Yus, Clement, Cocita, Lauren Alexandra, O'Neill, Sung-Yun, Kwon, Linda Sylvia, Klavinskis
Publikováno v:
Journal of Controlled Release
The generation of tissue resident memory (TRM) cells at the body surfaces to provide a front line defence against invading pathogens represents an important goal in vaccine development for a wide variety of pathogens. It has been widely assumed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66cb35c3966d692869e7432f3ebb6293
https://pubmed.ncbi.nlm.nih.gov/29056444
https://pubmed.ncbi.nlm.nih.gov/29056444
Autor:
Olivier D. Christophe, Andreas Schulze, Elisa Chisari, Allison P Dane, Azadeh Kia, Jalpa Pandya, Maria Portillo, Fabrizio Comper, Renee Kober, Segen Negash, Cécile V. Denis, Jonathan H. Foley, Florian Sonntag, Hattie Ollerton, Samantha Correia, Jenny McIntosh, Jaminder Khinder, Rebecca Alade, Jey Jeyakumar, Clement Cocita, Caterina Casari, Romuald Corbau, Dodev Tihomir, Erald Shehu
Publikováno v:
Blood. 134:4638-4638
Background: Several first-generation gene therapies are currently in clinical trials for Haemophilia A. These trials have to date exhibited varying results including issues with large patient to patient variation in FVIII levels and lack of durabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::489ef7d4d8af0a5659b8f2114ee06f39
https://doi.org/10.1182/blood-2019-128490
https://doi.org/10.1182/blood-2019-128490