Zobrazeno 1 - 10
of 349
pro vyhledávání: '"Clement C, Zai"'
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-30 (2024)
Abstract Excessive and persistent aggressiveness is the most common behavioral problem that leads to psychiatric referrals among children. While half of the variance in childhood aggression is attributed to genetic factors, the biological mechanism a
Externí odkaz:
https://doaj.org/article/1466454e336d45a085b54ffc5f16b07e
Autor:
Mahbod Ebrahimi, Kowsar Teymouri, Cheng C. Chen, Ayeshah G. Mohiuddin, Jennie G. Pouget, Vanessa F. Goncalves, Arun K. Tiwari, Clement C. Zai, James L. Kennedy
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Schizophrenia is a severe mental illness and a major risk factor for suicide, with approximately 50% of schizophrenia patients attempting and 10% dying from suicide. Although genetic components play a significant role in schizophrenia risk,
Externí odkaz:
https://doaj.org/article/fa91f42a67434a70979e8d00c0942ab5
Autor:
Niki Akbarian, Mahbod Ebrahimi, Fernanda C. Dos Santos, Sara Sadat Afjeh, Mohamed Abdelhack, Marcos Sanches, Andreea O. Diaconescu, Tarek K. Rajji, Daniel Felsky, Clement C. Zai, James L. Kennedy
Publikováno v:
Behavioral Sciences, Vol 14, Iss 10, p 876 (2024)
Cognitive decline is a public health concern affecting about 50 million individuals worldwide. Neuroticism, defined as the trait disposition to experience intense and frequent negative emotions, has been associated with an increased risk of late-life
Externí odkaz:
https://doaj.org/article/0c8836c7d76e448c9185f4a7e2642aae
Autor:
Xinyue Jiang, Clement C. Zai, Kody G. Kennedy, Yi Zou, Yuliya S. Nikolova, Daniel Felsky, L. Trevor Young, Bradley J. MacIntosh, Benjamin I. Goldstein
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract There is a gap in knowledge regarding the polygenic underpinnings of brain anomalies observed in youth bipolar disorder (BD). This study examined the association of a polygenic risk score for BD (BD-PRS) with grey matter structure and white
Externí odkaz:
https://doaj.org/article/a11a72e0b35f45e3a43839d6b62b5970
Autor:
Pasquale Paribello, Mirko Manchia, Ulker Isayeva, Marco Upali, Davide Orrù, Federica Pinna, Roberto Collu, Diego Primavera, Luca Deriu, Edoardo Caboni, Maria Novella Iaselli, Davide Sundas, Massimo Tusconi, Maria Scherma, Claudia Pisanu, Anna Meloni, Clement C. Zai, Donatella Congiu, Alessio Squassina, Walter Fratta, Paola Fadda, Bernardo Carpiniello
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7922 (2024)
Identifying phenotypes at high risk of suicidal behaviour is a relevant objective of clinical and translational research and can facilitate the identification of possible candidate biomarkers. We probed the potential association and eventual stabilit
Externí odkaz:
https://doaj.org/article/24f6dd2fe35e4257bb14b84d6932666b
Autor:
Mirko Manchia, Ulker Isayeva, Roberto Collu, Diego Primavera, Luca Deriu, Edoardo Caboni, Maria Novella Iaselli, Davide Sundas, Massimo Tusconi, Clement C. Zai, Maria Scherma, Alessio Squassina, Donatella Congiu, Pasquale Paribello, Federica Pinna, Claudia Pisanu, Anna Meloni, Walter Fratta, Paola Fadda, Bernardo Carpiniello
Publikováno v:
Mental Illness, Vol 2024 (2024)
Schizophrenia (SCZ) and schizoaffective disorder (SAD) are severe and complex psychiatric disorders whose liability threshold is modulated by the interplay of biological, mainly genetic, and environmental factors. Consistent evidence has pointed to t
Externí odkaz:
https://doaj.org/article/f67ca0f413e444469a23236b54af506a
Autor:
Tuana Kant, Emiko Koyama, Clement C. Zai, Marcos Sanches, Joseph H. Beitchman, James L. Kennedy
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21126- (2023)
Early adolescence is a crucial time for understanding and detecting the risk factors that may influence youth externalizing/disruptive behaviors and disorders. Previous literature reported evidence that risk factors for disruptive behaviors include c
Externí odkaz:
https://doaj.org/article/e215306776f6499da8a5d449f28d31e3
Autor:
Ulker Isayeva, Mirko Manchia, Roberto Collu, Luca Deriu, Diego Primavera, Alessio Squassina, Paola Fadda, Bernardo Carpiniello, Edoardo Caboni, Novella Iaselli, Davide Sundas, Massimo Tusconi, Federica Pinna, Pasquale Paribello, Maria Scherma, Claudia Pisanu, Anna Meloni, Donatella Congiu, Clement C. Zai, Walter Fratta
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S584- (2023)
Externí odkaz:
https://doaj.org/article/9456736524fd49e9b54f21604de9b35d
Autor:
Xinyue Jiang, Alysha A. Sultan, Mikaela K. Dimick, Clement C. Zai, James L. Kennedy, Bradley J. MacIntosh, Benjamin I. Goldstein
Publikováno v:
International Journal of Bipolar Disorders, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Background CACNA1C rs1006737 A allele, identified as a genetic risk variant for bipolar disorder (BD), is associated with anomalous functional connectivity in adults with and without BD. Studies have yet to investigate the association of CAC
Externí odkaz:
https://doaj.org/article/775bfe25bf7a456eb9694c7f703c68ed
Autor:
Yi Zou, Anahit Grigorian, Kody G. Kennedy, Clement C. Zai, Suyi Shao, James L. Kennedy, Ana C. Andreazza, Stephanie H. Ameis, Chinthaka Heyn, Bradley J. Maclntosh, Benjamin I. Goldstein
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Oxidative stress is associated with white matter diffusion metrics in adults with bipolar disorder (BD). We examined the association of single-nucleotide polymorphisms in the oxidative stress system, superoxide dismutase-2 (SOD2) rs4880 and
Externí odkaz:
https://doaj.org/article/80a09ab6fbd3436f8206783ccc6b69ea