Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Clemens. A. van Blitterswijk"'
Autor:
Sophie M.L. Neuen, Daan R.M.G. Ophelders, Helene Widowski, Matthias C. Hütten, Tim Brokken, Charlotte van Gorp, Peter G.J. Nikkels, Carmen A.H. Severens-Rijvers, Mireille M.J.P.E. Sthijns, Clemens A. van Blitterswijk, Freddy J. Troost, Vanessa L.S. LaPointe, Shahab Jolani, Christof Seiler, J. Jane Pillow, Tammo Delhaas, Niki L. Reynaert, Tim G.A.M. Wolfs
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 207-217 (2024)
Background: Perinatal inflammation increases the risk for bronchopulmonary dysplasia in preterm neonates, but the underlying pathophysiological mechanisms remain largely unknown. Given their anti-inflammatory and regenerative capacity, multipotent ad
Externí odkaz:
https://doaj.org/article/40d711cfe95e43a88d48f4c13f1731df
Autor:
Mireille M. J. P. E. Sthijns, Timo Rademakers, Jolien Oosterveer, Thomas Geuens, Clemens A. van Blitterswijk, Vanessa L. S. LaPointe
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
The pancreatic islets of Langerhans have low endogenous antioxidant levels and are thus especially sensitive to oxidative stress, which is known to influence cell survival and behaviour. As bioengineered islets are gaining interest for therapeutic pu
Externí odkaz:
https://doaj.org/article/24f7acadbc55416fa2a8e80a8e85d091
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
In regenerative medicine and tissue engineering, many materials are developed to mimic the extracellular matrix (ECM). However, these ECM-mimicking materials do not yet completely recapitulate the diversity and complexity of biological tissue-specifi
Externí odkaz:
https://doaj.org/article/68f9cdb6bf574020ac2f606ad71d17cd
Autor:
Fredrik C. Wieland, Mireille M.J.P.E. Sthijns, Thomas Geuens, Clemens A. van Blitterswijk, Vanessa L.S. LaPointe
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Pancreatic beta cells have inadequate levels of antioxidant enzymes, and the damage induced by oxidative stress poses a challenge for their use in a therapy for patients with type 1 diabetes. It is known that the interaction of the pancreatic endocri
Externí odkaz:
https://doaj.org/article/1de3a772069f49cd9323bdce5a233e5a
Autor:
Gustavo A. Higuera, Tiago Ramos, Antonio Gloria, Luigi Ambrosio, Andrea Di Luca, Nicholas Pechkov, Joost R. de Wijn, Clemens A. van Blitterswijk, Lorenzo Moroni
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The advantages of additive manufactured scaffolds, as custom-shaped structures with a completely interconnected and accessible pore network from the micro- to the macroscale, are nowadays well established in tissue engineering. Pore volume and archit
Externí odkaz:
https://doaj.org/article/bdb3132902ed42dabeb6a68340d4e292
Autor:
Ana I. Rodrigues, Rui L. Reis, Clemens A. van Blitterswijk, Isabel B. Leonor, Pamela Habibović
Publikováno v:
Biomaterials Research, Vol 21, Iss 1, Pp 1-11 (2017)
Abstract Background Bioinorganics have been explored as additives to ceramic bone graft substitutes with the aim to improve their performance in repair and regeneration of large bone defects. Silicon (Si), an essential trace element involved in the p
Externí odkaz:
https://doaj.org/article/519e457b1f4c4d7d8e89e1ec1f9fd0a4
Autor:
Erik J. Vrij, Yvonne S. Scholte op Reimer, Laury Roa Fuentes, Isabel Misteli Guerreiro, Viktoria Holzmann, Javier Frias Aldeguer, Giovanni Sestini, Bon-Kyoung Koo, Jop Kind, Clemens A. van Blitterswijk, Nicolas C. Rivron
Publikováno v:
Development (Cambridge), 149(20). Company of Biologists Ltd
Development, 149(20):dev192310. Company of Biologists Ltd
Development
Development, 149(20):dev192310. Company of Biologists Ltd
Development
Embryogenesis is supported by dynamic loops of cellular interactions. Here, we create a partial mouse embryo model to elucidate the principles of epiblast (Epi) and extra-embryonic endoderm co-development (XEn). We trigger naive mouse embryonic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b9bbcf3f5973f773d129fc7a0148b3
https://pure.knaw.nl/portal/en/publications/68d1c94d-eaa5-4672-8b61-3acbd4bcba2d
https://pure.knaw.nl/portal/en/publications/68d1c94d-eaa5-4672-8b61-3acbd4bcba2d
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 5 (2017)
Computational modeling has been increasingly applied to the field of tissue engineering and regenerative medicine. Where in early days computational models were used to better understand the biomechanical requirements of targeted tissues to be regene
Externí odkaz:
https://doaj.org/article/ee442b77a6ba45b5ba1d2ef9d834024b
Autor:
Maria G. Fois, Zeinab N. Tahmasebi Birgani, Alexander P. M. Guttenplan, Clemens A. van Blitterswijk, Stefan Giselbrecht, Pamela Habibović, Roman K. Truckenmüller
Publikováno v:
Small, 18(29):2202112. Wiley-VCH Verlag
In biomaterials R&D, conventional monolayer cell culture on flat/planar material samples, such as films, is still commonly employed at early stages of the assessment of interactions of cells with candidate materials considered for a biomedical applic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c4449c0a887363222d09e71af05404
https://pubmed.ncbi.nlm.nih.gov/35754160
https://pubmed.ncbi.nlm.nih.gov/35754160
Autor:
Anne M Leferink, Raluca M Fratila, Maaike A Koenrades, Clemens A van Blitterswijk, Aldrik Velders, Lorenzo Moroni
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115000 (2014)
Monitoring extracellular matrix (ECM) components is one of the key methods used to determine tissue quality in three-dimensional (3D) scaffolds for regenerative medicine and clinical purposes. This is even more important when multipotent human bone m
Externí odkaz:
https://doaj.org/article/3d42d2de136345f8b894c6959ce91ff8