Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Clemens von Bojničić-Kninski"'
Autor:
Felix E. Held, Anton A. Guryev, Tony Fröhlich, Frank Hampel, Axel Kahnt, Corina Hutterer, Mirjam Steingruber, Hanife Bahsi, Clemens von Bojničić-Kninski, Daniela S. Mattes, Tobias C. Foertsch, Alexander Nesterov-Mueller, Manfred Marschall, Svetlana B. Tsogoeva
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Heterocycles are ubiquitous in bioactive compounds and routes to different substitution patterns are important to access the full substrate space. Here the authors report a route to 4,5,7,8-substituted antiviral fluorescent quinazolines, to allow cel
Externí odkaz:
https://doaj.org/article/ca6b3826d1e94ad6b59eb0bddea12063
Autor:
Felix F. Loeffler, Tobias C. Foertsch, Roman Popov, Daniela S. Mattes, Martin Schlageter, Martyna Sedlmayr, Barbara Ridder, Florian-Xuan Dang, Clemens von Bojničić-Kninski, Laura K. Weber, Andrea Fischer, Juliane Greifenstein, Valentina Bykovskaya, Ivan Buliev, F. Ralf Bischoff, Lothar Hahn, Michael A. R. Meier, Stefan Bräse, Annie K. Powell, Teodor Silviu Balaban, Frank Breitling, Alexander Nesterov-Mueller
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Peptide arrays are used in areas such as measuring protein-protein interactions, but achieving high density in synthesis is challenging. Here, the authors report a method for the combinatorial synthesis of high density peptides arrays by laser driven
Externí odkaz:
https://doaj.org/article/87c83875d9e247549c186e22093d2d6b
Autor:
Tobias C. Foertsch, Alex T. Davis, Roman Popov, Clemens von Bojničić-Kninski, Felix E. Held, Svetlana B. Tsogoeva, Felix F. Loeffler, Alexander Nesterov-Mueller
Publikováno v:
Applied Sciences, Vol 9, Iss 7, p 1303 (2019)
We have observed the concentric deposition patterns of small molecules transferred by means of laser-induced forward transfer (LIFT). The patterns comprised different parts whose presence changed with the experimental constraints in a mode-like fashi
Externí odkaz:
https://doaj.org/article/22a63d3d39e043a687309509a46e0245
Autor:
Nesterov-Mueller, Felix Jenne, Sergey Biniaminov, Nathalie Biniaminov, Philipp Marquardt, Clemens von Bojničić-Kninski, Roman Popov, Anja Seckinger, Dirk Hose, Alexander
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3515
A novel resemblance-ranking peptide library with 160,000 10-meric peptides was designed to search for selective binders to antibodies. The resemblance-ranking principle enabled the selection of sequences that are most similar to the human peptidome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::f078e25a246ad5c784e99ebf8e38d7cd
Autor:
Felix, Jenne, Sergey, Biniaminov, Nathalie, Biniaminov, Philipp, Marquardt, Clemens, von Bojničić-Kninski, Roman, Popov, Anja, Seckinger, Dirk, Hose, Alexander, Nesterov-Mueller
Publikováno v:
International journal of molecular sciences. 23(7)
A novel resemblance-ranking peptide library with 160,000 10-meric peptides was designed to search for selective binders to antibodies. The resemblance-ranking principle enabled the selection of sequences that are most similar to the human peptidome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8e03118ac7ad9549b077ea23da21812
https://pubmed.ncbi.nlm.nih.gov/35408876
https://pubmed.ncbi.nlm.nih.gov/35408876
Autor:
Barbara Ridder, Frank Breitling, Daniela S. Mattes, Alexander Welle, Alexander Nesterov-Mueller, Clemens von Bojničić-Kninski, Felix F. Loeffler, Michael A. R. Meier, Tobias C. Foertsch
Publikováno v:
Applied Surface Science. 389:942-951
Poly(dimethylacrylamide) (PDMA) based matrix materials were developed for laser-based in situ solid phase peptide synthesis to produce high density arrays. In this specific array synthesis approach, amino acid derivatives are embedded into a matrix m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8493e45dcc014526e0e728df15d213fe
https://doi.org/10.1016/j.apsusc.2016.07.177
https://doi.org/10.1016/j.apsusc.2016.07.177
Autor:
Frank Breitling, Ute Schepers, Daniela S. Mattes, Bernhard Spengler, Barbara Ridder, Stephan W. Münch, Tobias C. Foertsch, Juliane Greifenstein, Stefan Bräse, Bettina Streit, Dhaka Ram Bhandari, Clemens von Bojničić-Kninski, Alexander Nesterov-Mueller, Felix F. Loeffler
Publikováno v:
Macromolecular rapid communications, 40 (6), Art.Nr.: 1800533
Macromolecular Rapid Communications
Macromolecular Rapid Communications
Here, the combinatorial synthesis of molecule arrays via a laser-assisted process is reported. Laser-transferred polymer nanolayers with embedded monomers, activators, or bases can be reliably stacked on top of each other, spot-by-spot, to synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8912edb973ef22919e6df3f77b46b6ee
Autor:
Alexander Nesterov-Mueller, Axel Kahnt, Frank Hampel, Manfred Marschall, Daniela S. Mattes, Tony Fröhlich, Corina Hutterer, Hanife Bahsi, Mirjam Steingruber, Anton A. Guryev, Svetlana B. Tsogoeva, Clemens von Bojničić-Kninski, Felix E. Held, Tobias C. Foertsch
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications, 8, Art. Nr.: 15071
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications, 8, Art. Nr.: 15071
Most of the known approved drugs comprise functionalized heterocyclic compounds as subunits. Among them, non-fluorescent quinazolines with four different substitution patterns are found in a variety of clinically used pharmaceuticals, while 4,5,7,8-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86f6c3f330688fc3878a027ae85f135
https://pubmed.ncbi.nlm.nih.gov/28462939
https://pubmed.ncbi.nlm.nih.gov/28462939
Autor:
Valentina Bykovskaya, Daniela S. Mattes, Frieder Maerkle, Clemens von Bojničić-Kninski, Roman Popov, Frank Breitling, Alexander Welle, Tobias C. Foertsch, Laura K. Weber, Alexander Nesterov-Mueller, Felix F. Loeffler, Barbara Ridder, Andrea Palermo
Publikováno v:
Advanced functional materials, 26 (39), 7067–7073
Microcavity arrays represent millions of different reaction compartments to screen, for example, molecular interactions, exogenous factors for cells or enzymatic activity. A novel method is presented to selectively synthesize different compounds in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e06ca3d38ce797418b32e72be2d69fa
Autor:
Daniela S. Mattes, Michael Hirtz, Frank Breitling, Felix F. Loeffler, Bettina Streit, Jordyn Atwater, Harald Fuchs, Clemens von Bojničić-Kninski
Publikováno v:
Advanced Materials. 30:1801632
Surface-bound microarrays of multiple oligo- and macromolecules (e.g., peptides, DNA) offer versatile options in biomedical applications like drug screening, DNA analysis, or medical diagnostics. Combinatorial syntheses of these molecules in situ can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f64ee19fe43fc1914664573635941fa
https://doi.org/10.1002/adma.201801632
https://doi.org/10.1002/adma.201801632