Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Clemens Stoffregen"'
Autor:
Thorsten Otto, Achim Wöckel, Agnieszka Korfel, Mattea Reinisch, Clemens Stoffregen, Norbert Marschner
Publikováno v:
Breast Care (Basel)
Introduction: Integration of patient preferences into shared decision making improves disease-related outcomes, but such data from patients with advanced breast cancer (aBC) are limited. The objective of this study was to demonstrate the relative imp
Autor:
Achim Wöckel, Thorsten Otto, Agnieszka Korfel, Clemens Stoffregen, Mattea Reinisch, Norbert Marschner
Publikováno v:
Cancer Research. 80:P1-17
Objective: This study aimed to identify patient preferences in aBC related to cancer treatment characteristics, i.e. to determine the relevance of gained lifetime (OS) and time to progression (PFS) in relation to quality of life (QoL) and therapy-ass
Autor:
Miguel Martin, Gregory L Price, Jens Huober, Stephen R. D. Johnston, Eriko Tokunaga, Sarah Shekarriz, M. Corona Gainford, Valerie Andre, Matthew P. Goetz, Masakazu Toi, Clemens Stoffregen, In Hae Park
Publikováno v:
The Oncologist
Background MONARCH 3, a phase III trial (NCT02246621) of postmenopausal women with hormone receptor–positive (HR+), human epidermal growth factor receptor 2–negative (HER2−) advanced breast cancer (ABC), previously demonstrated significantly im
Autor:
EM Grischke, Sarah Shekarriz, Masakazu Toi, Joohyuk Sohn, Valerie Andre, Gregory L Price, Gebra Cuyun Carter, Peter A. Kaufman, Patrick Neven, George W. Sledge, Clemens Stoffregen
Publikováno v:
The Oncologist
Background In the phase III MONARCH 2 study (NCT02107703), abemaciclib plus fulvestrant significantly improved progression‐free survival (PFS) versus placebo plus fulvestrant in patients with hormone receptor‐positive (HR+), HER2‐negative advan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45f893ac212ab7c69f433f4ac56ad26
https://lirias.kuleuven.be/handle/123456789/650756
https://lirias.kuleuven.be/handle/123456789/650756
Autor:
Thiery Gorlia, Marc Sanson, Clemens Stoffregen, Martin J. van den Bent, Myriam Gharib, Christina Lai, Denis Lacombe, Walter Taal, Roy Rampling, Rodney Decker
Publikováno v:
Neuro-Oncology, 14(3), 344-350. Oxford University Press
We report a phase 1 study to examine the safety and recommended dose of the oral protein kinase C-beta inhibitor (anti-angiogenic) enzastaurin in combination with single-agent temozolomide. The study was conducted in patients with recurrent glioblast
Autor:
Clemens Stoffregen, Robert A. Wolff, Anwar Hossain, Martin Fuchs, Steven J. Nicol, Maria Di Bartolomeo, Volker Heinemann
Publikováno v:
Cancer. 118:4132-4138
BACKGROUND: Enzastaurin and bevacizumab have demonstrated synergistic antitumor effects and, in phase 1 studies, the combination was well tolerated. This phase 2 study assessed enzastaurin with 5-fluorouracil/leucovorin plus bevacizumab as maintenanc
Autor:
Andreas, Böhle, Herbert, Leyh, Christian, Frei, Michael, Kühn, Reinhold, Tschada, Tobias, Pottek, Walter, Wagner, Helmut H, Knispel, Wolfgang, von Pokrzywnitzki, Ferruh, Zorlu, Karin, Helsberg, Birgit, Lübben, Victoria, Soldatenkova, Clemens, Stoffregen, Hartwig, Büttner, Zuhtu, Tansug
Publikováno v:
European Urology. 56:495-503
Background Recurrence prophylaxis with intravesical gemcitabine (GEM) was effective and safe in patients with non-muscle-invasive bladder cancer (NMIBC); efficacy as single-shot instillation remains to be proved. Objective To compare the efficacy of
Autor:
Clemens Stoffregen, Norman Rieger, Ute Ohnmacht, Jürgen Fischer, Christian Manegold, Marius Zemaitis, Harald Lahm
Publikováno v:
Lung Cancer. 56:115-123
The epigenetic inactivation of genes plays an important role in lung cancer. We have investigated the methylation status of the promoter region of seven genes (APC1A, DAPK, FHIT, p14(ARF), p16(INK4a), RARbeta, RASSF1A) in serum DNA of NSCLC patients.
Autor:
Amir Abdollahi, Marc Bischof, Klaus J. Weber, Ping Gong, J.ürgen Debus, Peter E. Huber, Kenneth E. Lipson, Clemens Stoffregen
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 60:1220-1232
Purpose: This is the first preclinical report evaluating a trimodal therapy consisting of irradiation, chemotherapy, and antiangiogenesis in the context of a multimodal anticancer strategy. The combination of the folate antimetabolite pemetrexed, SU5
Autor:
Clemens Stoffregen, Horst-Günter Rau, Volker Heinemann, Eckhart Dühmke, Martin Thoma, Andreas C.C. Wagner, Ralf Wilkowski
Publikováno v:
Strahlentherapie und Onkologie. 179:78-86
Die simultane Radiochemotherapie unter Verwendung von Gemcitabin scheint bei der Behandlung des Pankreaskarzinoms ein hoffnungsvoller Ansatz, da Gemcitabin als Monosubstanz oder in Kombination mit anderen Zytostatika eine verbesserte Wirksamkeit beim