Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Clemens Ries"'
Autor:
Chen Zhao, Clemens Ries, Ying Du, Jingwei Zhang, Kenji Sakimura, Keiichi Itoi, Jan M. Deussing
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Corticotropin-releasing hormone expressing (CRH+) neurons are distributed throughout the brain and play a crucial role in shaping the stress responses. Mouse models expressing site-specific recombinases (SSRs) or reporter genes are important tools pr
Externí odkaz:
https://doaj.org/article/11fe03d107be44ec8bb3678e6e6d6583
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: In recent years, purinergic signaling via the P2X7 receptor (P2X7R) on microglia has repeatedly been implicated in depression genesis. However, it remains unclear which role the human P2X7R (hP2X7R) plays in regulating both microglia mo
Externí odkaz:
https://doaj.org/article/9ae80fef3001404badcf7fb7a687465f
Autor:
Iven-Alex von Mücke-Heim, Lidia Urbina-Treviño, Joeri Bordes, Clemens Ries, Mathias V. Schmidt, Jan M. Deussing
Publikováno v:
Molecular psychiatry. 28(1)
Depressive disorders are the most burdensome psychiatric disorders worldwide. Although huge efforts have been made to advance treatment, outcomes remain unsatisfactory. Many factors contribute to this gridlock including suboptimal animal models. Espe