Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Clemens L. Bretscher"'
Autor:
Nathalie Legrand, Wibke E. Diederich, Clemens L. Bretscher, Svenja Zielke, Michael Daude, Till Adhikary, Barbara Fritz, Bernhard Wilke
Publikováno v:
Nucleic Acids Research
In the absence of ligands, the nuclear receptor PPARβ/δ recruits the NCOR and SMRT corepressors, which form complexes with HDAC3, to canonical target genes. Agonistic ligands cause dissociation of corepressors and enable enhanced transcription. Vic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2f6b45211467065d2f4f53873a764e
https://pubmed.ncbi.nlm.nih.gov/31428774
https://pubmed.ncbi.nlm.nih.gov/31428774
Autor:
Nathalie Legrand, Barbara Fritz, Clemens L. Bretscher, Svenja Zielke, Michael Daude, Bernhard Wilke, Till Adhikary, Wibke E. Diederich
Repression of transcription by nuclear receptors involves NCOR and SMRT corepressor complexes, which harbour the deacetylase HDAC3 as a subunit. Both deacetylase-dependent and -independent repression mechanisms have been reported for these complexes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af1ffe1b84e0dc67e8ca21c5eed9b2a
