Výsledky vyhledávání - "Clemens Furnsinn"

Akademický článek

Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis

Autor: Martina Theresa Hackl, Clemens Fürnsinn, Christina Maria Schuh, Martin Krssak, Fabrizia Carli, Sara Guerra, Angelika Freudenthaler, Sabina Baumgartner-Parzer, Thomas H. Helbich, Anton Luger, Maximilian Zeyda, Amalia Gastaldelli, Christoph Buettner, Thomas Scherer

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Obesity is associated with leptin resistance and rising blood leptin levels while central leptin exposure may be limited. Here, the authors show that brain leptin infusion reduces hepatic lipid content in rats by increasing hepatic VLDL secretion and

Externí odkaz: https://doaj.org/article/cd9c6af3dc684233ae9e0068539f7123

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Akademický článek

Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice.

Autor: Marianna Beghini, Theresia Wagner, Andreea Corina Luca, Matthäus Metz, Doris Kaltenecker, Katrin Spirk, Martina Theresa Hackl, Johannes Haybaeck, Richard Moriggl, Alexandra Kautzky-Willer, Thomas Scherer, Clemens Fürnsinn

Publikováno v: PLoS ONE, Vol 16, Iss 11, p e0260501 (2021)

The aim of this study was to investigate whether the lack of signal transducer and activator of transcription 5 (STAT5) in mature adipocytes of obese mice (Stat5Adipoq mice) improves glucose and lipid metabolism as previously observed in lean mice. M

Externí odkaz: https://doaj.org/article/6ef97d072bda445591f58230afa4de45

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Akademický článek

Periodized versus non-periodized swimming training with equal total training load: Physiological, molecular and performance adaptations in Wistar rats

Autor: Lucas D. M. Forte, Natália A. Rodrigues, André V. Cordeiro, Thais de Fante, Laís A. P. Simino, Adriana S. Torsoni, Márcio A. Torsoni, Claudio A. Gobatto, Fúlvia B. Manchado-Gobatto, Clemens Fürnsinn

Publikováno v: PLoS ONE, Vol 15, Iss 9 (2020)

This study investigated the effect of non-periodized training performed at 80, 100 and 120% of the anaerobic threshold intensity (AnT) and a linear periodized training model adapted for swimming rats on the gene expression of monocarboxylate transpor

Externí odkaz: https://doaj.org/article/113d9d8648fb4e338e18935b85e8e632

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Akademický článek

New proposed cut-off of waist circumference for central obesity as risk factor for diabetes mellitus: Evidence from the Indonesian Basic National Health Survey

Autor: Dante Saksono Harbuwono, Dicky Levenus Tahapary, Tri Juli Edi Tarigan, Em Yunir, Clemens Fürnsinn

Publikováno v: PLoS ONE, Vol 15, Iss 11 (2020)

Background Waist circumference (WC) measurement is practical to define central obesity. However, WC cut-off point might be differ based on different race or ethnicity. This study aims to analyze the optimal WC cut-off point to identify T2DM risk amon

Externí odkaz: https://doaj.org/article/4e3c74c6e8c74c8c960f0065a56be72f

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Akademický článek

Life Under Hypoxia Lowers Blood Glucose Independently of Effects on Appetite and Body Weight in Mice

Autor: Sameer Abu Eid, Martina T. Hackl, Mairam Kaplanian, Max-Paul Winter, Doris Kaltenecker, Richard Moriggl, Anton Luger, Thomas Scherer, Clemens Fürnsinn

Publikováno v: Frontiers in Endocrinology, Vol 9 (2018)

Blood glucose and the prevalence of diabetes are lower in mountain than lowland dwellers, which could among other factors be due to reduced oxygen availability. To investigate metabolic adaptations to life under hypoxia, male mice on high fat diet (H

Externí odkaz: https://doaj.org/article/ccc68ae1728945e68b4128255745499e

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Akademický článek

55P0110, a Novel Synthetic Compound Developed from a Plant Derived Backbone Structure, Shows Promising Anti-Hyperglycaemic Activity in Mice.

Autor: Barbara Brunmair, Zsuzsanna Lehner, Karin Stadlbauer, Immanuel Adorjan, Klaus Frobel, Thomas Scherer, Anton Luger, Leonhardt Bauer, Clemens Fürnsinn

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0126847 (2015)

Starting off with a structure derived from the natural compound multiflorine, a derivatisation program aimed at the discovery and initial characterisation of novel compounds with antidiabetic potential. Design and discovery of the structures was guid

Externí odkaz: https://doaj.org/article/cfb83a19a408451387640ce906788fe1

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