Zobrazeno 1 - 10 of 53 pro vyhledávání: '"Clemens Broger"'
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Akademický článek
Detect tissue heterogeneity in gene expression data with BioQC
Autor: Jitao David Zhang, Klas Hatje, Gregor Sturm, Clemens Broger, Martin Ebeling, Martine Burtin, Fabiola Terzi, Silvia Ines Pomposiello, Laura Badi
Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Gene expression data can be compromised by cells originating from other tissues than the target tissue of profiling. Failures in detecting such tissue heterogeneity have profound implications on data interpretation and reproducibi
Externí odkaz: https://doaj.org/article/e2f3d7cda6a14257b97e1a96f5781ae5
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2
Akademický článek
Correction to: Detect tissue heterogeneity in gene expression data with BioQC
Autor: Jitao David Zhang, Klas Hatje, Gregor Sturm, Clemens Broger, Martin Ebeling, Martine Burtin, Fabiola Terzi, Silvia Ines Pomposiello, Laura Badi
Publikováno v: BMC Genomics, Vol 19, Iss 1, Pp 1-1 (2018)
After the publication of this work [1], a mistake was noticed in the Eq. 1. Given an m × n expression matrix with m genes and samples of n tissues, the correct definition of the Gini index for gene i is:
Externí odkaz: https://doaj.org/article/37199c3e7e8f434b97ff79ea03b8bfb9
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3
Correction to: Detect tissue heterogeneity in gene expression data with BioQC
Autor: Clemens Broger, Martin Ebeling, Gregor Sturm, Jitao David Zhang, Klas Hatje, Fabiola Terzi, Silvia Pomposiello, Laura Badi, Martine Burtin
Publikováno v: BMC Genomics, Vol 19, Iss 1, Pp 1-1 (2018)
After the publication of this work [1], a mistake was noticed in the Eq. 1. Given an m × n expression matrix with m genes and samples of n tissues, the correct definition of the Gini index for gene i is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c561d1f9572b1e3ab170625bcd2d824
https://doi.org/10.1186/s12864-018-4940-2
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4
Detect tissue heterogeneity in gene expression data with BioQC
Autor: Martine Burtin, Silvia Pomposiello, Klas Hatje, Martin Ebeling, Gregor Sturm, Laura Badi, Clemens Broger, Fabiola Terzi, Jitao David Zhang
Publikováno v: BMC Genomics
BMC Genomics, BioMed Central, 2017, 18 (1), pp.277. 〈10.1186/s12864-017-3661-2〉
BMC Genomics, Vol 18, Iss 1, Pp 1-9 (2017)
BMC Genomics, 2017, 18 (1), pp.277. ⟨10.1186/s12864-017-3661-2⟩
BMC Genomics, BioMed Central, 2017, 18 (1), pp.277. ⟨10.1186/s12864-017-3661-2⟩
Background Gene expression data can be compromised by cells originating from other tissues than the target tissue of profiling. Failures in detecting such tissue heterogeneity have profound implications on data interpretation and reproducibility. A c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15724129e8433cd71edba95b73118dd1
http://www.hal.inserm.fr/inserm-01501219/document
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5
Statistical Methods for Analyzing Microarray Feature Data with Replications
Autor: Clemens Broger, Yaning Yang, Josephine Hoh, Jurg Ott, Klaus Lindpaintner, Martin Neeb, Joanne Edington
Publikováno v: Journal of Computational Biology. 10:157-169
Expression levels in oligonucleotide microarray experiments depend on a potentially large number of factors, for example, treatment conditions, different probes, different arrays, and so on. To dissect the effects of these factors on expression level
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c851c4fa2cf37d62a58340ac23482eb2
https://doi.org/10.1089/106652703321825946
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6
The staufen/pumilio Pathway Is Involved in Drosophila Long-Term Memory
Autor: Rod J. Scott, Uli Certa, Clemens Broger, John D. McNeil, Tim Tully, Lori Grady, Scott Gossweiler, Patrick Smith, Jody Barditch, Josh Dubnau, Ann-Shyn Chiang, Francois Buldoc
Publikováno v: Current Biology. 13:286-296
Background: Memory formation after olfactory learning in Drosophila displays behavioral and molecular properties similar to those of other species. Particularly, long-term memory requires CREB-dependent transcription, suggesting the regulation of "do
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f330004887c70602a43fd1232762c305
https://doi.org/10.1016/s0960-9822(03)00064-2
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7
Molecular cloning and functional characterization of human vesicular glutamate transporter 3
Autor: Clemens Broger, Shigeo Takamori, Pari Malherbe, Reinhard Jahn
Publikováno v: EMBO reports. 3:798-803
Glutamate is the major excitatory neurotransmitter in the mammalian CNS. It is loaded into synaptic vesicles by a proton gradient-dependent uptake system and is released by exocytosis upon stimulation. Recently, two mammalian isoforms of a vesicular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9175035b279b1d5ddffdaf8cdf4671ba
https://doi.org/10.1093/embo-reports/kvf159
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8
Crystal structure of phytase from Aspergillus ficuum at 2.5 Å resolution
Autor: A. P. G. M. Van Loon, Allan D'Arcy, David Mitchell, Clemens Broger, Dirk Kostrewa, F Grüninger-Leitch
Publikováno v: Nature Structural Biology. 4:185-190
Phytase is a high molecular weight acid phosphatase. The structure has an alpha/beta-domain similar to that of rat acid phosphatase and an alpha-domain with a new fold.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e702f12710fe6bb3fb1f68a85e2226e6
https://doi.org/10.1038/nsb0397-185
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9
A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance 1 1 Edited by T.Richmond
Autor: Peter Hartman, Rudolf L. Then, Clemens Broger, Hanno Langen, Malcolm G. P. Page, R. Dehoogt, Hans Locher, Allan D'Arcy, Beat Wipf, Glenn E. Dale, Synese Jolidon, A. M. Labhardt, Christian Oefner, Dietrich Stüber, Ivan Kompis
Publikováno v: Journal of Molecular Biology. 266:23-30
A single amino acid substitution, Phe98 to Tyr98, in dihydrofolate reductase (DHFR) is the molecular origin of trimethoprim (TMP) resistance in Staphylococcus aureus. This active site amino acid substitution was found in all S. aureus TMP-resistant c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74ea0308213458adab463ca5a426ea32
https://doi.org/10.1006/jmbi.1996.0770
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10
Cloning and Functional Expression of a Soluble Form of Kynurenine/α -Aminoadipate Aminotransferase from Rat Kidney
Autor: Pari Malherbe, Cesura Andrea, C. Köhler, Clemens Broger, Rico Buchli, Daniela Alberati-Giani
Publikováno v: Journal of Biological Chemistry. 270:29330-29335
Several aminotransferases with kynurenine aminotransferase (KAT) activity are able to convert L-kynurenine into kynurenic acid, a putative endogenous modulator of glutamatergic neurotransmission. In the rat, one of the described KAT isoforms has been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45b34e3c2ddb7656726c687cb8e5510
https://doi.org/10.1074/jbc.270.49.29330
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