Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Clemens AL"'
Autor:
Federica M. Conedera, Despina Kokona, Martin S. Zinkernagel, Jens V. Stein, Charles P. Lin, Clemens Alt, Volker Enzmann
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Retinal degeneration results from disruptions in retinal homeostasis due to injury, disease, or aging and triggers peripheral leukocyte infiltration. Effective immune responses rely on coordinated actions of resident microglia and
Externí odkaz:
https://doaj.org/article/916c1fd49e544c4fb67ae384fc06888f
Autor:
Federica M. Conedera, Judith M. Runnels, Jens V. Stein, Clemens Alt, Volker Enzmann, Charles P. Lin
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-22 (2023)
Abstract Background Retinal degeneration is a disease affecting the eye, which is an immune-privileged site because of its anatomical and physiological properties. Alterations in retinal homeostasis—because of injury, disease, or aging—initiate i
Externí odkaz:
https://doaj.org/article/f5536de96706455296677f8e9dd16d31
Publikováno v:
Molecules, Vol 29, Iss 10, p 2191 (2024)
CYP2A7 is one of the most understudied human cytochrome P450 enzymes and its contributions to either drug metabolism or endogenous biosynthesis pathways are not understood, as its only known enzymatic activities are the conversions of two proluciferi
Externí odkaz:
https://doaj.org/article/08c6a01705154627ab49281d8b481ae0
Autor:
Ivanka Jiménez-Dinamarca, Yolanda Prado, Pablo Tapia, Sebastian Gatica, Clemens Alt, Charles P. Lin, Cristian Reyes-Martínez, Carmen G. Feijóo, Cristobal Aravena, Alejandra González-Canacer, Simón Correa, Diego Varela, Claudio Cabello-Verrugio, Felipe Simon
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-32 (2023)
Abstract Background Sepsis is an uncontrolled inflammatory response against a systemic infection that results in elevated mortality, mainly induced by bacterial products known as endotoxins, producing endotoxemia. Disseminated intravascular coagulati
Externí odkaz:
https://doaj.org/article/c033d5e45ec04f8db7623330081fc0fe
Autor:
Ivanka Jiménez-Dinamarca, Yolanda Prado, Pablo Tapia, Sebastian Gatica, Clemens Alt, Charles P. Lin, Cristian Reyes-Martínez, Carmen G. Feijóo, Cristobal Aravena, Alejandra González-Canacer, Simón Correa, Diego Varela, Claudio Cabello-Verrugio, Felipe Simon
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/1e0a32b7491f4f75919eca01a9374c45
Autor:
Lukas Corbinian Harps, Annika Lisa Jendretzki, Clemens Alexander Wolf, Ulrich Girreser, Gerhard Wolber, Maria Kristina Parr
Publikováno v:
Molecules, Vol 28, Iss 20, p 7206 (2023)
The aim of this study was to develop and optimize a chiral HPLC-MS/MS method for quantitative analysis of (R)-/(S)-salbutamol and (R)-/(S)-salbutamol-4′-O-sulfate in human urine to allow for bioanalytical quantitation of the targeted analytes and i
Externí odkaz:
https://doaj.org/article/ee9f9d207b054df8b1ff7bf86746885d
Autor:
Clemens Albrecht, Serena Barbanotti, Heiko Hintz, Kai Jensch, Ronald Klos, Wolfgang Maschmann, Olaf Sawlanski, Matthias Stolper, Dieter Trines
Publikováno v:
EPJ Techniques and Instrumentation, Vol 8, Iss 1, Pp 1-20 (2021)
Abstract At DESY the ALPS II experiment is being installed in the HERA tunnel to search for axion like particles. A laser beam will be injected into the magnetic field of a string of superconducting (s.c.) dipole magnets, available from the HERA prot
Externí odkaz:
https://doaj.org/article/4f8bef66821b4433852991fcb30a61a2
Autor:
Jie Zhao, Sijie Liu, Clemens Alexander Wolf, Gerhard Wolber, Maria Kristina Parr, Matthias Bureik
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3022 (2022)
Alprazolam is a triazolobenzodiazepine which is most commonly used in the short-term management of anxiety disorders, often in combination with antipsychotics. The four human members of the CYP3A subfamily are mainly responsible for its metabolism, w
Externí odkaz:
https://doaj.org/article/82a27b674beb4fb09c7099637fcefd04
Autor:
Theresa Noonan, Katrin Denzinger, Valerij Talagayev, Yu Chen, Kristina Puls, Clemens Alexander Wolf, Sijie Liu, Trung Ngoc Nguyen, Gerhard Wolber
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1304 (2022)
G protein-coupled receptors (GPCRs) are amongst the most pharmaceutically relevant and well-studied protein targets, yet unanswered questions in the field leave significant gaps in our understanding of their nuanced structure and function. Three-dime
Externí odkaz:
https://doaj.org/article/9708fe59db2b4f2d8494de1cfdd31267
Autor:
Raphaël Turcotte, Clemens Alt, Judith M. Runnels, Kyoko Ito, Juwell W. Wu, Walid Zaher, Luke J. Mortensen, Lev Silberstein, Daniel C. Côté, Andrew L. Kung, Keisuke Ito, Charles P. Lin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Transplantation of a single hematopoietic stem cell is an important method for its functional characterization, but the standard transplantation protocol relies on cell homing to the bone marrow after intravenous injection. Here, we present
Externí odkaz:
https://doaj.org/article/9ecda607d1944f4292e9b9f4fd7e0a35