Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Clemens, Mellink"'
Autor:
Marco V. Haselager, Rachel Thijssen, Danique Bax, Demi Both, Francien De Boer, Simon Mackay, Julie Dubois, Clemens Mellink, Arnon P. Kater, Eric Eldering
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 1112-1128 (2023)
Preventing or overcoming resistance to the Bcl‐2 inhibitor venetoclax is an emerging unmet clinical need in patients with chronic lymphocytic leukaemia (CLL). The upregulation of anti‐apoptotic Bcl‐2 members through signalling pathways within t
Externí odkaz:
https://doaj.org/article/2e43009de0ac4b10a008f5313a882ab0
Autor:
Arnon Kater, Julie Dubois, Christian Brieghel, Sabina Kersting, Lisbeth Enggaard, Gerrit Veldhuis, Rogier Mous, Clemens Mellink, Johan Dobber, Christian Poulsen, Caspar Da Cunha-Bang, Hendrik Fredriksen, Ann Janssens, Ida Schjodt, Ellen Dompeling, Juha Ranti, Mattias Mattsson, Mar Bellido, Hoa Tran, Kazem Nasserinejad, Mark-David Levin, Carsten Niemann
Publikováno v:
HemaSphere, Vol 7, p e10648ed (2023)
Externí odkaz:
https://doaj.org/article/37b50e3544da4e5e91dc8c9be88c63dc
Autor:
Arnon Kater, Rosemary Harrup, Thomas J Kipps, Barbara Eichhorst, Carolyn J Owen, Sarit Assouline, Nicole Lamanna, Tadeusz Robak, Javier de la Serna, Ulrich Jaeger, Guillaume Cartron, Marco Montillo, Clemens Mellink, Brenda Chyla, Maria Thadani-Mulero, Marcus Lefebure, Yanwen Jiang, Rosemary Millen, Michelle Boyer, John F Seymour
Publikováno v:
HemaSphere, Vol 7, p e492813f (2023)
Externí odkaz:
https://doaj.org/article/40a72c8b5e324b6bb0a316c864da72a7
Autor:
Sabina Kersting, Mark-David Levin, Julie Dubois, Yvette van Norden, Johan Dobber, Yvonne Jauw, Anne-Marie van der Kevie-Kersemaekers, Clemens Mellink, Caspar Da Cunha-Bang, Leonie Van Desr Burg, Doreen Te Raa, Fransien de Boer, Jolanda Droogendijk, Cecile Idink, Koen De Heer, Marten Nijziel, Lidwine Tick, Inge Ludwig, Mathijs Silbermann, Aart Beeker, Mar Bellido, Ludo Evers, Gerben Zwezerijnen, Josée Zijlstra, Marcel Kap, Carsten Niemann, Arnon Kater
Publikováno v:
HemaSphere, Vol 7, p e797861a (2023)
Externí odkaz:
https://doaj.org/article/def1784e57be41248dd5770881eba9b2
Autor:
Panagiotis Baliakas, Blanca Espinet, Clemens Mellink, Marie Jarosova, Anastasia Athanasiadou, Paolo Ghia, Arnon P. Kater, David Oscier, Claudia Haferlach, Kostas Stamatopoulos, on behalf of ERIC, the European Research Initiative on CLL
Publikováno v:
HemaSphere, Vol 6, Iss 4, p e707 (2022)
Mounting evidence underscores the clinical value of cytogenetic analysis in chronic lymphocytic leukemia (CLL), particularly as it allows the identification of complex karyotype, that has recently emerged as a prognostic and potentially predictive bi
Externí odkaz:
https://doaj.org/article/db18f21a7b4040c0b11e396454345a67
Autor:
Alexander C. Leeksma, Panagiotis Baliakas, Theodoros Moysiadis, Anna Puiggros, Karla Plevova, Anne-Marie van der Kevie-Kersemaekers, Hidde Posthuma, Ana E. Rodriguez-Vicente, Anh Nhi Tran, Gisela Barbany, Larry Mansouri, Rebeqa Gunnarsson, Helen Parker, Eva van den Berg, Mar Bellido, Zadie Davis, Meaghan Wall, Ilaria Scarpelli, Anders Österborg, Lotta Hansson, Marie Jarosova, Paolo Ghia, Pino Poddighe, Blanca Espinet, Sarka Pospisilova, Constantine Tam, Loïc Ysebaert, Florence Nguyen-Khac, David Oscier, Claudia Haferlach, Jacqueline Schoumans, Marian Stevens-Kroef, Eric Eldering, Kostas Stamatopoulos, Richard Rosenquist, Jonathan C. Strefford, Clemens Mellink, Arnon P. Kater
Publikováno v:
Haematologica, Vol 106, Iss 1 (2020)
Complex karyotype (CK) identified by chromosome-banding analysis (CBA) has shown prognostic value in chronic lymphocytic leukemia (CLL). Genomic arrays offer high-resolution genome-wide detection of copy-number alterations (CNAs) and could therefore
Externí odkaz:
https://doaj.org/article/b0edf60d944d4c6fab629017cf3cd09c
Autor:
Marten Hansen, Eszter Varga, Tatjana Wüst, Clemens Mellink, Anne-Marie van der Kevie-Kersemaekers, Marieke von Lindern, Emile van den Akker
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 42-45 (2017)
Mobilized peripheral blood (MPB) CD34+ cells were differentiated to CD34+/CD41+ megakaryoblasts. Cells were sorted to obtain a pure megakaryoblast population which was reprogrammed with a hOKSM self-silencing polycistronic lentiviral vector. Resultin
Externí odkaz:
https://doaj.org/article/f717d64c255d4e09b6b8655e1b9d9213
Autor:
Marten Hansen, Eszter Varga, Tatjana Wüst, Clemens Mellink, Anne-Marie van der Kevie-Kersemaekers, Anne E. Marneth, Marieke von Lindern, Bert van der Reijden, Emile van den Akker
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 34-37 (2017)
Peripheral blood mononuclear cells were isolated from an individual harboring a heterozygous c.859C → T p.Q287* mutation in GFI1B, causing an autosomal dominant bleeding disorder, platelet type, 17 (BDPLT17). PBMCs were differentiated to erythrobla
Externí odkaz:
https://doaj.org/article/91a2cfd943dd436f9e9a8fa9f4e6c4e8
Autor:
Mark-David Levin, Sabina Kersting, Julie M.N. Dubois, Yvette Norden, Johan A Dobber, Yvonne W.S. Jauw, Anne-Marie van der Kevie-Kersemaekers, Clemens Mellink, Koen de Heer, Leonie van der Burg, Doreen Te Raa, Fransien de Boer, Jolanda Droogendijk, Cecile Idink, Marten R. Nijziel, Lidwine W. Tick, Inge Ludwig, Matthijs Silbermann, Aart Beeker, Mar Bellido, Ludo M. Evers, Gerben JC Zwezerijnen, Carsten U Niemann, Arnon P. Kater
Publikováno v:
Blood. 140:4137-4139
Autor:
Sabina Kersting, Julie Dubois, Kazem Nasserinejad, Johan A Dobber, Clemens Mellink, Anne-Marie F van der Kevie-Kersemaekers, Ludo M Evers, Fransien de Boer, Harry R Koene, John Schreurs, Marjolein van der Klift, Gerjo A Velders, Ellen van der Spek, Hanneke M van der Straaten, Mels Hoogendoorn, Michel van Gelder, Eduardus F M Posthuma, Hein P J Visser, Ilse Houtenbos, Cecile A M Idink, Djamila E Issa, Ellen C Dompeling, Henk C T van Zaanen, Hendrik Veelken, Henriette Levenga, Lidwine W Tick, Wim E Terpstra, Sanne H Tonino, Michelle Boyer, Mehrdad Mobasher, Mark-David Levin, Arnon P Kater
Publikováno v:
The Lancet Haematology, 9(3), e190-e199. Lancet Publishing Group
The Lancet Haematology, 9(3), E190-E199. ELSEVIER SCI LTD
The Lancet Haematology, 9(3), E190-E199. ELSEVIER SCI LTD
Background Fixed-duration 12 cycles of venetoclax plus obinutuzumab is established as first-line treatment for patients with chronic lymphocytic leukaemia. We aimed to determine the activity and safety of 12 cycles of venetoclax consolidation after f