Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Clemens, Cammann"'
Autor:
Nuria Tubío-Santamaría, Ashok Kumar Jayavelu, Tina M. Schnoeder, Theresa Eifert, Chen-Jen Hsu, Florian Perner, Qirui Zhang, Daniela V. Wenge, Fynn M. Hansen, Joanna M. Kirkpatrick, Nidhi Jyotsana, Steven W. Lane, Björn von Eyss, Aniruddha J. Deshpande, Michael W. M. Kühn, Juerg Schwaller, Clemens Cammann, Ulrike Seifert, Frédéric Ebstein, Elke Krüger, Andreas Hochhaus, Michael Heuser, Alessandro Ori, Matthias Mann, Scott A. Armstrong, Florian H. Heidel
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-21 (2023)
Abstract Pharmacologic targeting of chromatin-associated protein complexes has shown significant responses in KMT2A-rearranged (KMT2A-r) acute myeloid leukemia (AML) but resistance frequently develops to single agents. This points to a need for thera
Externí odkaz:
https://doaj.org/article/32a44bd3490c43d78d23fc64b13aaac5
Autor:
Stefan Weiss, Silva Holtfreter, Tanja C. Meyer, Frieder Schmiedeke, Clemens Cammann, Marcus Dörr, Stephan B. Felix, Hans J. Grabe, Georg Homuth, Christian Kohler, Cedric Mahncke, Stephan Michalik, Matthias Nauck, Nele Friedrich, Stefanie Samietz, Henry Völzke, Uwe Völker, Barbara M. Bröker
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Life-threatening toxic shock syndrome is often caused by the superantigen toxic shock syndrome toxin-1 (TSST-1) produced by Staphylococcus aureus. A well-known risk factor is the lack of neutralizing antibodies. To identify determinants of the anti-T
Externí odkaz:
https://doaj.org/article/d6828816c1094dd5b7230f0895346ec9
Autor:
Clemens Cammann, Nicole Israel, Sarah Frentzel, Andreas Jeron, Eylin Topfstedt, Thomas Schüler, Luca Simeoni, Martin Zenker, Hans Joerg Fehling, Burkhart Schraven, Dunja Bruder, Ulrike Seifert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Upon antigen recognition by the T cell receptor (TCR), a complex signaling network orchestrated by protein-tyrosine kinases (PTKs) and protein-tyrosine phosphatases (PTPs) regulates the transmission of the extracellular signal to the nucleus. The rol
Externí odkaz:
https://doaj.org/article/31a0a97d2f9f4dbeb8c340c3bfd11b06
Autor:
Thomas Sura, Vanessa Gering, Clemens Cammann, Sven Hammerschmidt, Sandra Maaß, Ulrike Seifert, Dörte Becher
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Epithelial cells are an important line of defense within the lung. Disruption of the epithelial barrier by pathogens enables the systemic dissemination of bacteria or viruses within the host leading to severe diseases with fatal outcomes. Thus, the l
Externí odkaz:
https://doaj.org/article/88e9debfd75c4e919d73659e14213914
Autor:
Stephan Michalik, Florian Siegerist, Raghavendra Palankar, Kati Franzke, Maximilian Schindler, Alexander Reder, Ulrike Seifert, Clemens Cammann, Jan Wesche, Leif Steil, Christian Hentschker, Manuela Gesell-Salazar, Emil Reisinger, Martin Beer, Nicole Endlich, Andreas Greinacher, Uwe Völker
Publikováno v:
Haematologica, Vol 107, Iss 4 (2022)
Vector-based SARS-CoV-2 vaccines have been associated with vaccine- induced thrombosis with thrombocytopenia syndrome (VITT/TTS), but the causative factors are still unresolved. We comprehensively analyzed the ChAdOx1 nCoV-19 (AstraZeneca) and Ad26.C
Externí odkaz:
https://doaj.org/article/98a7cf58d6ae47778258e4ba016d16dd
Autor:
Theresa Lowinus, Florian H. Heidel, Tanima Bose, Subbaiah Chary Nimmagadda, Tina Schnöder, Clemens Cammann, Ingo Schmitz, Ulrike Seifert, Thomas Fischer, Burkhart Schraven, Ursula Bommhardt
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Treatment of acute leukemia is challenging and long-lasting remissions are difficult to induce. Innovative therapy approaches aim to complement standard chemotherapy to improve drug efficacy and decrease toxicity. Promising new th
Externí odkaz:
https://doaj.org/article/58bd27f1c33f445fa05b8617cf253f3b
Autor:
Timothy French, Nicole Israel, Henning Peter Düsedau, Anne Tersteegen, Johannes Steffen, Clemens Cammann, Eylin Topfstedt, Daniela Dieterich, Thomas Schüler, Ulrike Seifert, Ildiko Rita Dunay
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cell survival and function critically relies on the fine-tuned balance of protein synthesis and degradation. In the steady state, the standard proteasome is sufficient to maintain this proteostasis. However, upon inflammation, the sharp increase in p
Externí odkaz:
https://doaj.org/article/936f06c69d9c410a925c61cbc4750d32
Autor:
Jan Wesche, Lisa Colberg, Ulrike Seifert, Clemens Cammann, Eylin Topfstedt, Andreas Greinacher
Publikováno v:
Transfusion. 61:2746-2755
Objectives Characterization of the proteasome and its stability in buffy-coat derived platelet concentrates (PCs) during storage. Background The proteasome plays a key role in cell homeostasis by processing misfolded or abnormal proteins and regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692315d78455bd7e4d9350320290eb22
https://doi.org/10.1111/trf.16605
https://doi.org/10.1111/trf.16605
Autor:
Christian Thomas, Nadine Gelbrich, Alexander Mustea, Matthias B Stope, Maria A Oster, Holger H.H. Erb, Clemens Cammann
Publikováno v:
Anticancer Research. 41:3271-3279
Background/aim Androgen receptor (AR) degradation is the primary regulator of androgen receptor activity. This study was designed to investigate the influence of the proteasome on AR protein stability after enzalutamide (Enz) treatment. Materials and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b48415996b68a3c0039a525e3edf92c
https://doi.org/10.21873/anticanres.15113
https://doi.org/10.21873/anticanres.15113
Autor:
Uwe Völker, Raghavendra Palankar, Manuela Gesell-Salazar, Andreas Greinacher, Martin Beer, Clemens Cammann, Maximilian Schindler, Christian Hentschker, Kati Franzke, Nicole Endlich, Leif Steil, Emil Reisinger, Jan Wesche, Stephan Michalik, Florian Siegerist, Alexander Reder, Ulrike Seifert
Vector-based SARS-CoV-2 vaccines have been associated with vaccine-induced thrombosis with thrombocytopenia syndrome (VITT/TTS), but the causative factors are still unresolved. We comprehensively analyzed ChAdOx1 nCov-19 (AstraZeneca) and Ad26.COV2.S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0eb191f331b921b202fcdfc502aea5d
https://doi.org/10.21203/rs.3.rs-736157/v1
https://doi.org/10.21203/rs.3.rs-736157/v1
