Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Clemencia Colmenares"'
Autor:
Clemencia Colmenares, Amit Verma, Kith Pradhan, H. Leighton Grimes, Chinavenmeni S. Velu, David E. Muench, Nathan Salomonis, Matthew T. Weirauch, Kyle Ferchen, Kashish Chetal, Xiaoting Chen
Publikováno v:
Blood. 132:e24-e34
The transforming growth factor beta (TGF-β) signaling pathway controls hematopoietic stem cell (HSC) behavior in the marrow niche; however, TGF-β signaling becomes chronic in early-stage myelodysplastic syndrome (MDS). Although TGF-β signaling nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ff22ff1954b5342892d2c5084bfdb4
https://doi.org/10.1182/blood-2018-06-860890
https://doi.org/10.1182/blood-2018-06-860890
Publikováno v:
Medical Science Educator. 23:88-91
The impact of research experiences on medical student career intentions is unclear. Short-term outcomes from the Cleveland Clinic Lerner College of Medicine’s five-year research curriculum show that most medical students can generate scholarly work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fc05cb26c2f608b43026f7a1f5b863
https://doi.org/10.1007/bf03341812
https://doi.org/10.1007/bf03341812
Chromosomal instability in mouse embryonic fibroblasts null for the transcriptional co-repressor Ski
Autor:
Katherine Marcelain, Jessica Toro, Adam Aguirre, Nobuhide Ueki, Michael J. Hayman, Clemencia Colmenares, Ricardo Armisen
Publikováno v:
Journal of Cellular Physiology. 227:278-287
Ski is a transcriptional regulator that has been considered an oncoprotein given its ability to induce oncogenic transformation in avian model systems. However, studies in mouse and in some human tumor cells have also indicated a tumor suppressor act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8945446013b2a93aff055ac4dece2c98
https://doi.org/10.1002/jcp.22733
https://doi.org/10.1002/jcp.22733
Publikováno v:
Medical Science Educator. 21:67-77
The Cleveland Clinic Lerner College of Medicine (CCLCM) was established as one of three tracks in the Case Western Reserve University (CWRU) School of Medicine Program to prepare physician investigators through rigorous, comprehensive, longitudinal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c9f16003e8e9d76b7d6db894195a944
https://doi.org/10.1007/bf03341600
https://doi.org/10.1007/bf03341600
Autor:
David Muench, Kyle Ferchen, Chinavenmeni S. Velu, Kith Pradhan, Kashish Chetal, Clemencia Colmenares, Amit Verma, Nathan Salomonis, H. Leighton Grimes
Publikováno v:
Blood. 132:4350-4350
The transforming growth factor-beta (TGFβ) signaling pathway controls hematopoietic stem cell (HSC) behavior in the marrow niche; however, TGFb signaling becomes chronic in early-stage myelodysplasia (MDS) where it may select MDS-genic HSC clones. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::572be7406215a1b0e54fa30b984dfd43
https://doi.org/10.1182/blood-2018-99-119441
https://doi.org/10.1182/blood-2018-99-119441
Autor:
Véronique Lefebvre, Kotaro J. Kaneko, Melvin L. DePamphilis, Alfredo Penzo-Méndez, Alex Vassilev, Pallavi Bhattaram, Clemencia Colmenares, Elisabeth Sock, Michael Wegner
Publikováno v:
Nature Communications
During organogenesis, neural and mesenchymal progenitor cells give rise to many cell lineages, but their molecular requirements for self-renewal and lineage decisions are incompletely understood. In this study, we show that their survival critically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e165e1b796977f1dc4ae6a7e07de25
http://europepmc.org/articles/PMC2892298
http://europepmc.org/articles/PMC2892298
Autor:
Clemencia Colmenares, Peter Young, Lukas Sommer, Suzana Atanasoski, Ed Stavnezer, François Castagner, Dies Meijer, Hye Youn Lee, Lucia Notterpek, Ueli Suter, Markus U. Ehrengruber
Publikováno v:
Neuron, 43, 499-511. Cell Press
Neuron
Neuron
Schwann cell proliferation and subsequent differentiation to nonmyelinating and myelinating cells are closely linked processes. Elucidating the molecular mechanisms that control these events is key to the understanding of nerve development, regenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b75c281ffeefd05b6841a2b02773fb
Autor:
Jun Harada, Ping Dai, Clemencia Colmenares, Matiullah Khan, Shunsuke Ishii, Renu Wadhwa, Teruaki Nomura, Hiroshi Sasaki, Sunil C. Kaul, Hiroshi Akimaru, Toshie Shinagawa
Publikováno v:
Genes & Development. 16:2843-2848
Transcription factor Glioblastoma-3 (Gli3) is cleaved in the anterior region of the limb bud to generate its repressor form. In contrast, Sonic hedgehog (Shh) signaling from the posterior zone of polarizing activity blocks Gli3 processing and then in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187b278653bcda850a09825bded0f747
https://doi.org/10.1101/gad.1017302
https://doi.org/10.1101/gad.1017302
Autor:
Angela Hosack, Joseph H. Nadeau, Benedicte Christensen, David S. Rosenblatt, David Sankoff, James L. McGrath, Allen E. Bale, Clemencia Colmenares, Orval A. Mamer, Rudi Balling, Mitchell Rodier, Brian M. Gilfix, Sheila Ernest
Publikováno v:
Mammalian Genome. 13:259-267
Hyperhomocysteinemia adversely affects fundamental aspects of fetal development, adulthood, and aging, but the role of elevated homocysteine levels in these birth defects and adult diseases remains unclear. Mouse models are valuable for investigating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90d72539bfcdd4a50275f35396ef8a9
https://doi.org/10.1007/s00335-001-3054-2
https://doi.org/10.1007/s00335-001-3054-2
Autor:
Isao Kohno, Shunsuke Ishii, Sunil C. Kaul, Teruaki Nomura, Haidong Dong, Renu Wadhwa, Clemencia Colmenares, Matiullah Khan
Publikováno v:
Genes & Development. 13:412-423
The N-CoR/SMRT complex containing mSin3 and histone deacetylase (HDAC) mediates transcriptional repression by nuclear hormone receptors and Mad. The proteins encoded by the ski proto-oncogene family directly bind to N-CoR/SMRT and mSin3A, and forms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bff1f0471281f67045aaf4409c43a0
https://doi.org/10.1101/gad.13.4.412
https://doi.org/10.1101/gad.13.4.412