Synthesis and evaluation of novel benzotropolones as Atg4B inhibiting autophagy blockers

Autor: Tanc, Muhammet, Cleenewerck, Matthias, Kurdi, Ammar, Roelandt, Ria, Declercq, Wim, De Meyer, Guido, Augustyns, Koen, Martinet, Wim, Van der Veken, Pieter

Publikováno v: In Bioorganic Chemistry June 2019 87:163-168

Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay

Autor: Cleenewerck, Matthias, Grootaert, Mandy O.J., Gladysz, Rafaela, Adriaenssens, Yves, Roelandt, Ria, Joossens, Jurgen, Lambeir, Anne-Marie, De Meyer, Guido R.Y., Declercq, Wim, Augustyns, Koen, Martinet, Wim, Van der Veken, Pieter

Publikováno v: In European Journal of Medicinal Chemistry 10 November 2016 123:631-638

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

Autor: Li, You, Reeves, Rachel M., Wang, Xin, Bassat, Quique, Brooks, W. Abdullah, Cohen, Cheryl, Moore, David P., Nunes, Marta, Rath, Barbara, Campbell, Harry, Nair, Harish, Acacio, Sozinho, Alonso, Wladimir J., Antonio, Martin, Ayora Talavera, Guadalupe, Badarch, Darmaa, Baillie, Vicky L., Barrera-Badillo, Gisela, Bigogo, Godfrey, Broor, Shobha, Bruden, Dana, Buchy, Philippe, Byass, Peter, Chipeta, James, Clara, Wilfrido, Dang, Duc-Anh, de Freitas Lazaro Emediato, Carla Cecilia, de Jong, Menno, Diaz-Quinonez, Jose Alberto, Do, Lien Anh Ha, Fasce, Rodrigo A., Feng, Luzhao, Ferson, Mark J., Gentile, Angela, Gessner, Bradford D., Goswami, Doli, Goyet, Sophie, Grijalva, Carlos G., Halasa, Natasha, Hellferscee, Orienka, Hessong, Danielle, Homaira, Nusrat, Jara, Jorge, Kahn, Kathleen, Khuri-Bulos, Najwa, Kotloff, Karen L., Lanata, Claudio F., Lopez, Olga, Lopez Bolanos, Maria Renee, Lucero, Marilla G., Lucion, Florencia, Lupisan, Socorro P., Madhi, Shabir A., McCracken, John P., Mekgoe, Omphile, Moraleda, Cinta, Moyes, Jocelyn, Mulholland, Kim, Munywoki, Patrick K., Naby, Fathima, Thanh Hung Nguyen, Nicol, Mark P., Nokes, D. James, Noyola, Daniel E., Onozuka, Daisuke, Palani, Nandhini, Poovorawan, Yong, Rahman, Mustafizur, Ramaekers, Kaat, Romero, Candice, Schlaudecker, Elizabeth P., Schweiger, Brunhilde, Seidenberg, Phil, Simoes, Eric A. F., Singleton, Rosalyn, Sistla, Sujatha, Sturm-Ramirez, Katharine, Suntronwong, Nungruthai, Sutanto, Agustinus, Tapia, Milagritos D., Thamthitiwat, Somsak, Thongpan, Ilada, Tillekeratne, Gayani, Tinoco, Yeny O., Treurnicht, Florette K., Turner, Claudia, Turner, Paul, van Doorn, Rogier, Van Ranst, Marc, Visseaux, Benoit, Waicharoen, Sunthareeya, Wang, Jianwei, Yoshida, Lay-Myint, Zar, Heather J., Shi, Ting, Zhang, Shanshan, Openshaw, Peter, Wedzicha, Jadwicha, Falsey, Ann, Miller, Mark, Beutels, Philippe, Bont, Louis, Pollard, Andrew, Molero, Eva, Martinon-Torres, Federico, Heikkinen, Terho, Meijer, Adam, Fischer, Thea Kolsen, van den Berge, Maarten, Giaquinto, Carlo, Mikolajczyk, Rafael, Hackett, Judy, Dillon, Laura, Tafesse, Eskinder, Cai, Bing, Knirsch, Charles, Lopez, Antonio Gonzalez, Dieussaert, Ilse, Dermateau, Nadia, Leach, Amanda, Stoszek, Sonia K., Gallichan, Scott, Kieffer, Alexia, Demont, Clarisse, Denouel, Angeline, Cheret, Arnaud, Gavart, Sandra, Aerssens, Jeroen, Wyffels, Veronique, Cleenewerck, Matthias, Fuentes, Robert, Rosen, Brian

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
The Lancet Global Health
The Lancet Global Health, 7(8), E1031-E1045. ELSEVIER SCI LTD
Li, Y, Reeves, R M, Wang, X, Bassat, Q, Brooks, W A, Cohen, C, Moore, D P, Nunes, M, Rath, B, Campbell, H, Nair, H, Acacio, S, RSV Global Epidemiology Network, Alonso, W J, Antonio, M, Ayora Talavera, G, Badarch, D, Baillie, V L, Barrera-Badillo, G, Bigogo, G, Broor, S, Bruden, D, Buchy, P, Byass, P, Chipeta, J, Clara, W, Dang, D-A, de Freitas Lázaro Emediato, C C, de Jong, M, Díaz-Quiñonez, J A, Do, L A H, Fasce, R A, Feng, L, Ferson, M J, Gentile, A, Gessner, B D, Goswami, D, Goyet, S, Grijalva, C G, Halasa, N, Hellferscee, O, Hessong, D, Homaira, N, Jara, J, Kahn, K, Khuri-Bulos, N, Kotloff, K L, Lanata, C F, Lopez, O, Lopez Bolaños, M R, de Jong, M, Yoshida, L-M, Zar, H J & RESCEU investigators 2019, ' Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis ', The Lancet Global Health, vol. 7, no. 8, pp. e1031-e1045 . https://doi.org/10.1016/S2214-109X(19)30264-5
Li, Y, Reeves, R, Wang, X, Bassat, Q, Brooks, A W, Cohen, C, Moore, D, Nunes, M C & Rath, B A & Campbell, H & Nair, H 2019, ' Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis ', The Lancet Global Health . https://doi.org/10.1016/S2214-109X(19)30264-5
The Lancet Global Health, 7(8), e1031-e1045. Elsevier BV
lancet global health, 7(8), e1031-e1045. Elsevier BV
The Lancet Global Health, Vol 7, Iss 8, Pp e1031-e1045 (2019)

BACKGROUND: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d47c1f326ad8ed08568703697ae0a2
https://doi.org/10.1016/s2214-109x(19)30264-5

Immunological and Inflammatory Biomarkers of Susceptibility and Severity in Adult Respiratory Syncytial Virus Infections

Autor: Wiseman, Dexter J, Thwaites, Ryan S, Drysdale, Simon B, Janet, Sophie, Donaldson, Gavin C, Wedzicha, Jadwiga A, Openshaw, Peter J, Nair, Harish, Campbell, Harry, Shi, Ting, Zhang, Shanshan, Li, You, Openshaw, Peter, Wedzicha, Jadwiga, Falsey, Ann, Miller, Mark, Beutels, Philippe, Bont, Louis, Pollard, Andrew, Molero, Eva, Martinon-Torres, Federico, Heikkinen, Terho, Meijer, Adam, Kølsen Fischer, Thea, van den Berge, Maarten, Giaquinto, Carlo, Mikolajczyk, Rafael, Hackett, Judy, Tafesse, Eskinder, Cai, Bing, Knirsch, Charles, Gonzalez Lopez, Antonio, Dieussaert, Ilse, Dermateau, Nadia, Stoszek, Sonia, Gallichan, Scott, Kieffer, Alexia, Demont, Clarisse, Cheret, Arnaud, Gavart, Sandra, Aerssens, Jeroen, Wyffels, Veronique, Cleenewerck, Matthias, Fuentes, Robert, Rosen, Brian

Publikováno v: S591
S584
The Journal of Infectious Diseases

BackgroundRespiratory syncytial virus (RSV) is the most common cause of bronchiolitis in young infants. However, it is also a significant pathogen in older adults. Validated biomarkers of RSV disease severity would benefit diagnostics, treatment deci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e06fb21171eeabb32f638da5ead055b

Discovery of novel Atg4B inhibitors with a benzotropolone core structure and therapeutic evaluation in a HT29 colon carcinoma mouse xenograft model

Autor: Cleenewerck, Matthias

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2097::756d4fafb4654bf2eb51895505fd4cb3
https://hdl.handle.net/10067/1387530151162165141