Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

Autor: Fulcher, J, Mihaylova, B, O'Connell, R, Emberson, J, Blackwell, L, Reith, C, Koren, M, Tonkin, A, Ridker, P, Barnes, E, Ford, I, Kean, S, Trompet, S, Macfarlane, P, Cannon, C, Pedersen, TR, Wilhelmsen, L, LaRosa, J, Packard, C, Robertson, M, Young, R, Tobert, J, Flather, M, Goto, S, Kastelein, J, Newman, C, Shear, C, Varigos, J, White, H, Armitage, J, Davies, K, Halls, H, Harper, C, Herrington, W, Holland, L, Kirby, A, Oconnell, R, Preiss, D, Spata, E, Wilson, K, Lonn, E, Wanner, C, Koenig, W, Gotto, A, Kjekshus, J, Yusuf, S, Collins, R, Simes, J, Baigent, C, Keech, A, De Lemos, J, Braunwald, E, Blazing, M, Murphy, S, Downs, JR, Clearfield, M, Holdaas, H, Gordon, D, Davis, B, Dahlof, B, Poulter, N, Sever, P, Knopp, RH, Fellstrom, B, Jardine, A, Schmieder, R, Zannad, F, Colhoun, HM, Betteridge, DJ, Durrington, PN, Hitman, GA, Fuller, J, Neil, A, Sacks, F, Moye, L, Pfeffer, M, Hawkins, CM, Wedel, H, Wikstrand, J, Krane, V, Tavazzi, L, Maggioni, A, Marchioli, R, Tognoni, G, Franzosi, MG, Bowman, L, Landray, MJ, Parish, S, Peto, R, Sleight, P, Ridker, PM, Macmahon, S, Marschner, I, Shaw, J, Serruys, PW, Nakamura, H, Knatterud, G, Furberg, C, Byington, R, Sattar, N, Jukema, JW

Publikováno v: Lancet (London, England)
J Fam Pract
2019, ' Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials ', The Lancet, vol. 393, no. 10170, pp. 407-415 . https://doi.org/10.1016/S0140-6736(18)31942-1

Background: Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203a87637a419ad172911cdd27325c83
http://hdl.handle.net/10044/1/67913

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PROTOCOL FOR A PROSPECTIVE COLLABORATIVE OVERVIEW OF ALL CURRENT AND PLANNED RANDOMIZED TRIALS OF CHOLESTEROL TREATMENT REGIMENS

Autor: DOWNS, J, GOTTO, A, CLEARFIELD, M, GORDON, D, MANOLIO, T, GOLDBOURT, U, KAPLINSKY, E, MOYE, L, SACKS, F, PFEFFER, M, HAWKINS, C, BRAUNWALD, E, FRANZOSI, M, MAGGIONI, A, TOGNONI, G, ROBINS, S, RUBINS, H, SIMES, J, KEECH, A, MACMAHON, S, TONKIN, A, YUSUF, S, FLATHER, M, COLLINS, R, ARMITAGE, J, BAIGENT, C, PETO, R, SLEIGHT, P, KNATTERUD, G, KJEKSHUS, J, PEDERSEN, T, WILHELMSEN, L, ROUSSOUW, J, PROBSTFIELD, J, COBBE, S, MACFARLANE, P, SHEPHERD, J

Publikováno v: AMERICAN JOURNAL OF CARDIOLOGY. 75(16)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::44a1c75351059ca633e368eace1abdaa
http://ora.ox.ac.uk/objects/uuid:23a5621a-75aa-4454-861b-06d9b1c79f25

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