Zobrazeno 1 - 10
of 770
pro vyhledávání: '"Clear cell renal cell carcinoma (ccRCC)"'
Publikováno v:
The Egyptian Journal of Radiology and Nuclear Medicine, Vol 55, Iss 1, Pp 1-13 (2024)
Abstract Background The detection of small renal masses has significantly increased due to the widespread use of cross-sectional imaging in recent years. Among these masses, clear cell renal cell carcinoma (ccRCC) is the most common subtype and progr
Externí odkaz:
https://doaj.org/article/84d07f25929040868dcac11fb323efaf
Autor:
Maite Emaldi, Esther Rey-Iborra, Ángela Marín, Lorena Mosteiro, David Lecumberri, Tove Øyjord, Noémie Roncier, Gunhild M. Mælandsmo, Javier C. Angulo, Peio Errarte, Gorka Larrinaga, Rafael Pulido, José I. López, Caroline E. Nunes-Xavier
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Immune checkpoint inhibitors in combination with tyrosine kinase inhibitors (TKIs) are improving the response rates of advanced renal cancer patients. However, many treated patients do not respond, making novel immune checkpoint-based immunotherapies
Externí odkaz:
https://doaj.org/article/949a689eebfb4f5cad6f292d3f117000
Autor:
Mohamed Sakr, Merhan Badran, Sarah Ahmed Hassan, Mohamed Elsaqa, Mohamed Anwar Elwany, Nevine M. F. El Deeb, Mohamed Sharafeldeen
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-8 (2024)
Abstract Introduction Renal cell carcinoma (RCC) is the dominant primary renal malignant neoplasm, encompassing a significant portion of renal tumors. The presence of synchronous yet histologically distinct ipsilateral RCCs, however, is an exceptiona
Externí odkaz:
https://doaj.org/article/0410b07b5ec0456bbc35209685ceae36
Autor:
Yufei Wang, Alicia Buck, Brandon Piel, Luann Zerefa, Nithyassree Murugan, Christian D. Coherd, Andras G. Miklosi, Haraman Johal, Ricardo Nunes Bastos, Kun Huang, Miriam Ficial, Yasmin Nabil Laimon, Sabina Signoretti, Zhou Zhong, Song-My Hoang, Gabriella M. Kastrunes, Marion Grimaud, Atef Fayed, Hsien-Chi Yuan, Quang-De Nguyen, Tran Thai, Elena V. Ivanova, Cloud P. Paweletz, Ming-Ru Wu, Toni K. Choueiri, Jon O. Wee, Gordon J. Freeman, David A. Barbie, Wayne A. Marasco
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract One of the major hurdles that has hindered the success of chimeric antigen receptor (CAR) T cell therapies against solid tumors is on-target off-tumor (OTOT) toxicity due to sharing of the same epitopes on normal tissues. To elevate the safe
Externí odkaz:
https://doaj.org/article/90de263ab4864245afd1b4be5c061876
Autor:
Xiao Jing, Xiangcheng Qin, Hao Liu, Huanhuan Liu, Huina Wang, Jiayue Qin, Yanui Zhang, Shanbo Cao, Xiaodong Fan
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)
Abstract Background DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic responses. Nonetheless, the characteristics and significance of DDR alterations in clear cell renal cell carcinoma (ccRCC) remain undefined. This
Externí odkaz:
https://doaj.org/article/2412f0ddee8e42009ad02f0fe2ecef41
Autor:
Ziwei Gui, Juan Du, Nan Wu, Ningning Shen, Zhiqing Yang, Huijun Yang, Xuzhi Wang, Na Zhao, Zixin Zeng, Rong Wei, Wenxia Ma, Chen Wang
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-24 (2023)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most common renal malignancy, although newly developing targeted therapy and immunotherapy have been showing promising effects in clinical treatment, the effective biomarkers for immu
Externí odkaz:
https://doaj.org/article/c8552c5f001649249d981da8833cd390
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27354- (2024)
Clear cell renal cell carcinoma (ccRCC) is known as the most common type of renal cancer. Recently, a series of advances have been made in targeted therapy for ccRCC. To combat this highly metastatic tumor, novel therapeutic targets still need to be
Externí odkaz:
https://doaj.org/article/f7104b7a028b4282a46b9436bb0b4f3d
Publikováno v:
Biomolecules & Biomedicine, Vol 24, Iss 2 (2024)
Although the immune factor interferon gamma-inducible protein 30 (IFI30) has been linked to the growth and immune infiltration of various malignancies, its function and mechanism in clear cell renal cell carcinoma (ccRCC) remains unclear. We used sev
Externí odkaz:
https://doaj.org/article/19ed633f417d466fad201e662e319f93
Autor:
Hongquan Liu, Xiaoqing Liang, Gonglin Tang, Xiaofeng Wang, Zhen Wang, Leijie Tong, Qiancheng Mao, Jian Ma, Jitao Wu
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26094- (2024)
Clear cell renal cell carcinoma (ccRCC) is an aggressive malignant tumor. Disulfidptosis is a new programmed cell death mechanism, which is characterized by the abnormal accumulation of intracellular disulfides that are highly toxic to cells. However
Externí odkaz:
https://doaj.org/article/b078da9c0bc841c38fcf6b39ea908ff3
Autor:
Zehua Sun, Yumei Zhang, Yuanhao Xia, Xinru Ba, Qingyin Zheng, Jing Liu, Xiaojing Kuang, Haizhu Xie, Peiyou Gong, Yinghong Shi, Ning Mao, Yongtao Wang, Ming Liu, Chao Ran, Chenchen Wang, Xiaoni Wang, Min Li, Wei Zhang, Zishuo Fang, Wanchen Liu, Hao Guo, Heng Ma, Yang Song
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24456- (2024)
Background: Clear cell renal cell carcinoma (ccRCC) is corelated with tumor-associated material (TAM), coagulation system and adipocyte tissue, but the relationships between them have been inconsistent. Our study aimed to explore the cut-off interval
Externí odkaz:
https://doaj.org/article/75f0833f91d2440dae93e3435589cdeb