Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Clea Barcena"'
Autor:
Muxin Gu, Sruthi Cheloor Kovilakam, William Dunn, Ludovica Marando, Clea Barcena, Irina Mohorianu, Siddhartha Kar, Margarete Fabre, Moritz Gerstung, Pedro Quiros, George S Vassiliou
Publikováno v:
HemaSphere, Vol 7, p e53186b7 (2023)
Externí odkaz:
https://doaj.org/article/8c077ba512714a22ab8df55899a828df
Autor:
Sruthi Cheloor Kovilakam, Muxin Gu, William G. Dunn, Ludovica Marando, Clea Barcena, Serena Nik Zainal, Irina Mohorianu, Siddhartha P. Kar, Margarete A. Fabre, Pedro M. Quiros, George S. Vassiliou
Publikováno v:
HemaSphere, Vol 7, p e363625f (2023)
Externí odkaz:
https://doaj.org/article/8a678ccaaaf744899007bb7fdd197b43
Autor:
Siddhartha P. Kar, Pedro M. Quiros, Muxin Gu, Tao Jiang, Jonathan Mitchell, Ryan Langdon, Vivek Iyer, Clea Barcena, M. S. Vijayabaskar, Margarete A. Fabre, Paul Carter, Slavé Petrovski, Stephen Burgess, George S. Vassiliou
Publikováno v:
Kar, S 2022, ' Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis ', Nature Genetics, vol. 54, no. 8, pp. 1155-1166 . https://doi.org/10.1038/s41588-022-01121-z
Funder: British Heart Foundation
Clonal hematopoiesis (CH), the clonal expansion of a blood stem cell and its progeny driven by somatic driver mutations, affects over a third of people, yet remains poorly understood. Here we analyze genetic data
Clonal hematopoiesis (CH), the clonal expansion of a blood stem cell and its progeny driven by somatic driver mutations, affects over a third of people, yet remains poorly understood. Here we analyze genetic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a566ede948c8c0f43687cd347842c3
Publikováno v:
Blood advances. 6(7)
Autor:
Pedro M. Quirós, Yaiza Español, Rebeca Acín-Pérez, Francisco Rodríguez, Clea Bárcena, Kenta Watanabe, Enrique Calvo, Marta Loureiro, M. Soledad Fernández-García, Antonio Fueyo, Jesús Vázquez, José Antonio Enríquez, Carlos López-Otín
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 542-556 (2014)
We generated mice deficient in Lon protease (LONP1), a major enzyme of the mitochondrial quality control machinery. Homozygous deletion of Lonp1 causes early embryonic lethality, whereas its haploinsufficiency protects against colorectal and skin tum
Externí odkaz:
https://doaj.org/article/c628e3a772344fb6bec50e4f632d1921
Autor:
Jana Key, Aneesha Kohli, Clea Bárcena, Carlos López-Otín, Juliana Heidler, Ilka Wittig, Georg Auburger
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4523 (2019)
Research on healthy aging shows that lifespan reductions are often caused by mitochondrial dysfunction. Thus, it is very interesting that the deletion of mitochondrial matrix peptidase LonP1 was observed to abolish embryogenesis, while deletion of th
Externí odkaz:
https://doaj.org/article/3224e4cae5524145b2c190c5e9281e6b