Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Clayton Mansel"'
Autor:
Benjamin R. Troutwine, Taylor A. Strope, Edziu Franczak, Colton R. Lysaker, Laylan Hamid, Clayton Mansel, Julia A. Stopperan, Cynthia M. Gouvion, Mohammad Haeri, Russell H. Swerdlow, Heather M. Wilkins
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105781- (2022)
Introduction: Mitochondrial dysfunction is observed in Alzheimer's disease (AD). However, the relationship between functional mitochondrial deficits and AD pathologies is not well established in human subjects. Methods: Post-mortem human brain tissue
Externí odkaz:
https://doaj.org/article/582d0d131aae48a1957bd062e00a2945
Publikováno v:
British Journal of Healthcare Management. 27:1-10
Background/Aims The National Innovation Accelerator was developed in 2014 to increase the uptake of innovation across the NHS by providing strategic funding to candidates. This study aimed to critically evaluate the success of the National Innovation
Autor:
Maud Gratuze, Johannes C.M. Schlachetzki, Ricardo D’Oliveira Albanus, Nimansha Jain, Brenna Novotny, Logan Brase, Lea Rodriguez, Clayton Mansel, Michal Kipnis, Sydney O’Brien, Martina P. Pasillas, Choonghee Lee, Melissa Manis, Marco Colonna, Oscar Harari, Christopher K. Glass, Jason D. Ulrich, David M. Holtzman
Publikováno v:
Neuron.
In addition to tau and Aβ pathologies, inflammation plays an important role in Alzheimer's disease (AD). Variants in APOE and TREM2 increase AD risk. ApoE4 exacerbates tau-linked neurodegeneration and inflammation in P301S tau mice and removal of mi
Autor:
Bhupinder P.S. Vohra, Paul D. Klawinski, Jesse Rose, Clayton Mansel, Emily Dema, Shaneann Fross, Haley Hart, Alexis Mann
Publikováno v:
Neurotoxicology and Teratology. 72:58-70
Lead (Pb) is a teratogen that poses health risks after acute and chronic exposure. Lead is deposited in the bones of adults and is continuously leached into the blood for decades. While this chronic lead exposure can have detrimental effects on adult
Publikováno v:
Neurochemistry International. 121:86-97
Golgi fragmentation and loss of Nicotinamide Mononucleotide Adenylyltransferase 2 (NMNAT2) are the early key features of many neurodegenerative disorders. We investigated the link between NMNAT2 loss, Golgi fragmentation and axon degeneration. Golgi
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 180(2)
Tributyltin (TBT) remains a global health concern. The primary route of human exposure to TBT is either through ingestion or skin absorption, but TBT’s effects on the peripheral nervous system have still not been investigated. Therefore, we exposed