Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Clayton M. Crabtree"'
Autor:
Piyali Dasgupta, Brandon S. Shiflett, Yi C. Chen, Haitao Luo, A. Betts Carpenter, Cody A. Stover, Christopher A. McNees, W. Elaine Hardman, Theodore R. Witte, Aaron M. Dom, Clayton M. Crabtree, Brent A. Thornhill, Kathleen C. Brown, Jamie K. Lau
Recent case-controlled clinical studies show that bronchioalveolar carcinomas (BAC) are correlated with smoking. Nicotine, the addictive component of cigarettes, accelerates cell proliferation through nicotinic acetylcholine receptors (nAChR). In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560db06c9ce3d2ecbbec341bd23ae10d
https://doi.org/10.1158/0008-5472.c.6505077
https://doi.org/10.1158/0008-5472.c.6505077
Autor:
Piyali Dasgupta, Brandon S. Shiflett, Yi C. Chen, Haitao Luo, A. Betts Carpenter, Cody A. Stover, Christopher A. McNees, W. Elaine Hardman, Theodore R. Witte, Aaron M. Dom, Clayton M. Crabtree, Brent A. Thornhill, Kathleen C. Brown, Jamie K. Lau
PDF file - 490K, Figure S1: Cell line authentication data Figure S2: Full screen western blots for ChAT, VAChT, AChE and CHT1 Figure S3: Immunohistochemistry of ChAT and VAChT in normal human lung tissues Figure S4: Nicotine-induced ACh production in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045b3ec2806f8cd75d7f28b2b4620077
https://doi.org/10.1158/0008-5472.22398489.v1
https://doi.org/10.1158/0008-5472.22398489.v1
Autor:
W. Elaine Hardman, William D. Rollyson, C. Luke Damron, Kathleen C. Brown, Haley E. Perry, J. Michael Brown, Jamie K. Lau, Theodore R. Witte, Brent A. Thornhill, Cathryn D. Stevenson, A. Betts Carpenter, Monica A. Valentovic, Clayton M. Crabtree, Rebecca G. Creel, Piyali Dasgupta, Aaron M. Dom, John G. Ball
Publikováno v:
Apoptosis. 19:1190-1201
Capsaicin, the pungent ingredient of chili peppers, displays potent anti-neoplastic activity in a wide array of human cancer cells. The present manuscript examines the signaling pathways underlying the apoptotic activity of capsaicin in human small c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0630cf0612a93811c1cc7d7aaf34320
https://doi.org/10.1007/s10495-014-1007-y
https://doi.org/10.1007/s10495-014-1007-y
Autor:
Dennie V. Jones, Haley E. Perry, Kathleen C. Brown, Haitao Luo, Piyali Dasgupta, Jamie K. Lau, Brent A. Thornhill, Clayton M. Crabtree, Joseph Pulliam, Yi Charlie Chen
Publikováno v:
The Journal of Biological Chemistry
Background: Nicotine promotes the proliferation of human squamous cell lung cancer (SCC-L) via the α7-nicotinic receptor (nAChR). Results: Nicotine increases α7-nAChR expression via transcriptional mechanisms involving Sp1 and GATA proteins. Conclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1960e04ddfae4e6175bd734fe967e8
http://europepmc.org/articles/PMC3829154
http://europepmc.org/articles/PMC3829154
Autor:
Jamie K. Lau, Clayton M. Crabtree, Brent A. Thornhill, Carla Cook, Nalini Santanam, Kathleen C. Brown, Piyali Dasgupta
Publikováno v:
Atherosclerosis. 225:264-273
Smoking is a major risk factor for the development of atherosclerosis, stroke and myocardial infarction. Cigarette smoke consists of a complex mixture of about 4000 compounds. Out of these, polycyclic hydrocarbons, tobacco-specific nitrosamines, oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d60d54dd5bb8ef6e3ae083e76bc2ed
https://doi.org/10.1016/j.atherosclerosis.2012.07.041
https://doi.org/10.1016/j.atherosclerosis.2012.07.041
Autor:
Haitao Luo, Yashoni H. Shah, Aileen J. Marcelo, Nancy A. Proper, Theodore R. Witte, Piyali Dasgupta, W. Elaine Hardman, Jamie K. Lau, Aaron M. Dom, Clayton M. Crabtree, Elsa I. Mangiarua, Kathleen C. Brown, Brandon S. Shiflett, Richard D. Egleton, Yi Charlie Chen
Publikováno v:
Angiogenesis. 15:99-114
Small cell lung cancer (SCLC) demonstrates a strong etiological association with smoking. Although cigarette smoke is a mixture of about 4,000 compounds, nicotine is the addictive component of cigarette smoke. Several convergent studies have shown th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea8be4f2ee22923cfdb7b11c0c1703b
https://doi.org/10.1007/s10456-011-9246-9
https://doi.org/10.1007/s10456-011-9246-9
Autor:
Joseph Pulliam, Piyali Dasgupta, Kathleen C. Brown, Dennie V. Jones, Brent A. Thornhill, Jamie Lau, Haley E. Perry, Yi Charlie Chen, Clayton M. Crabtree
Publikováno v:
The FASEB Journal. 28
Smoking has a strong association with the development of squamous cell carcinomas of the lung (SCC-L). Nicotine, the addictive component of cigarettes, promotes the proliferation of SCC-Ls via the ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71cfb39c19a86eb672111638741e9629
https://doi.org/10.1096/fasebj.28.1_supplement.405.4
https://doi.org/10.1096/fasebj.28.1_supplement.405.4
Autor:
Kathleen C. Brown, Theodore R. Witte, Yi Charlie Chen, Jamie Lau, Clayton M. Crabtree, A B. Carpenter, Brent A. Thornhill, Piyali Dasgupta, Christopher A. McNees, Aaron M. Dom, W Hardman, Cody A. Stover
Publikováno v:
The FASEB Journal. 28
Clinical studies show that the development of lung adenocarcinomas (LACs) is correlated with smoking habits. Nicotine, the addictive component of cigarettes, accelerates human LAC proliferation thr...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb895ec71f299f795d388e00f86c1ac8
https://doi.org/10.1096/fasebj.28.1_supplement.151.3
https://doi.org/10.1096/fasebj.28.1_supplement.151.3
Autor:
Cathryn D. Stevenson, Haley E. Perry, Cody A. Stover, William D. Rollyson, Theodore R. Witte, W Hardman, Clayton M. Crabtree, Kathleen C. Brown, Aaron M. Dom, Piyali Dasgupta, Jamie Lau
Publikováno v:
The FASEB Journal. 28
Capsaicin, spicy ingredient of chili peppers, is used to topically treat pain and inflammation associated with a variety of diseases. Data from our laboratory shows that capsaicin displays apoptoti...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf43fe499da5192729340f0023c8d9c2
https://doi.org/10.1096/fasebj.28.1_supplement.644.2
https://doi.org/10.1096/fasebj.28.1_supplement.644.2
Autor:
Piyali Dasgupta, C Damron, Aaron M. Dom, Clayton M. Crabtree, Kathleen C. Brown, Cathryn D. Stevenson, Theodore R. Witte, Jamie Lau, W Hardman, Yi Chen, Rebecca G. Creel
Publikováno v:
The FASEB Journal. 28
Small cell lung cancer (SCLC) is characterized by aggressive clinical course and a dismal survival rate. The present study examines the apoptotic activity of capsaicin (the pungent ingredient of chili peppers) in human SCLC. We observed that capsaici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3677e56f53527d52cdc3090f7c59d99a
https://doi.org/10.1096/fasebj.28.1_supplement.644.8
https://doi.org/10.1096/fasebj.28.1_supplement.644.8