Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Clayton M. Bullock"'
Publikováno v:
Molecular Pharmacology. 65:582-588
Prokineticins are cysteine-rich secreted proteins that regulate diverse biological processes, including gastrointestinal motility, angiogenesis, and circadian rhythms. Two closely related G protein-coupled receptors that mediate signal transduction o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f8a72e880ea4fff0771a3c010eff8e
https://doi.org/10.1124/mol.65.3.582
https://doi.org/10.1124/mol.65.3.582
Autor:
Jin-Long Chen, Qun-Yong Zhou, Frederick J. Ehlert, Hui Tian, Clayton M. Bullock, Daniel C.-H. Lin
Publikováno v:
Journal of Biological Chemistry. 277:19276-19280
We previously described two mammalian secreted proteins, prokineticin 1 and prokineticin 2, that potently contract gastrointestinal smooth muscle. Prokineticin 1 has also been shown to promote angiogenesis by stimulating proliferation, migration, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672980be72e6acbb447d61f3ae98c7a8
https://doi.org/10.1074/jbc.m202139200
https://doi.org/10.1074/jbc.m202139200
Publikováno v:
European Journal of Cell Biology. 81:77-85
Summary Truncations at the carboxyl termini of G protein-coupled receptors result in defective receptor biogenesis and comprise a number of inherited disorders. In order to evaluate the structural role of the C-terminus in G protein-coupled receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58cb82caf46ae81fdb2cb2f1380654d
https://doi.org/10.1078/0171-9335-00222
https://doi.org/10.1078/0171-9335-00222
Publikováno v:
Nature Cell Biology. 3:492-498
Many structural determinants for G protein-coupled receptor (GPCR) functions have been defined, but little is known concerning the regulation of their transport from the endoplasmic reticulum (ER) to the cell surface. Here we show that a carboxy-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c158b612eb8a48081ab33e42bb5414
https://doi.org/10.1038/35074561
https://doi.org/10.1038/35074561
Publikováno v:
Molecular Pharmacology. 59:692-698
The motility of gastrointestinal tract is regulated by classical neurotransmitters, neuropeptides, and humoral agents. Two novel human cDNAs have been cloned based on their sequence similarity to a frog skin secretion protein, Bv8, and a nontoxic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fdfe047681a48645b977c8a5092d51
https://doi.org/10.1124/mol.59.4.692
https://doi.org/10.1124/mol.59.4.692
Autor:
Robert C. Tyler, Robert C. Unfer, Cornelia Gorman, Molly McClarrion, David M. Rodman, Karen A. Fagan, Clayton M. Bullock
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 277:L1199-L1204
We report gene transfer to the normal and injured murine pulmonary circulation via systemic (intravascular) and airway (intratracheal) delivery of novel polycationic liposomes (imidazolium chloride, imidazolinium chloride-cholesterol, and ethyl phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21d37cda9467077721f734f8ff24eb6
https://doi.org/10.1152/ajplung.1999.277.6.l1199
https://doi.org/10.1152/ajplung.1999.277.6.l1199
Autor:
Lee G. Fradkin, Molly Mcclarrinon, Ed Fox, Lee B. Bussey, Lisa Roche, Clayton M. Bullock, Cornelia Gorman, Bryan Fox, Leslie Gilkey, Denny Liggitt, Virginia Watral
Publikováno v:
DNA and Cell Biology. 18:533-547
As the sequencing of the human genome proceeds, the need for a new screen for in vivo function is becoming apparent. Many investigators are turning to various transgenic models as a means of studying function. However, these approaches are very time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2992cdadc9a1858716f6efde479e8b72
https://doi.org/10.1089/104454999315088
https://doi.org/10.1089/104454999315088
Autor:
Jason C. Bermak, Michelle Y. Cheng, Clayton M. Bullock, Qun-Yong Zhou, David R. Weaver, James D. Belluzzi, Alex G. Lee, Frances M. Leslie, Chuanyu Li
Publikováno v:
Nature. 417(6887)
The suprachiasmatic nucleus (SCN) controls the circadian rhythm of physiological and behavioural processes in mammals. Here we show that prokineticin 2 (PK2), a cysteine-rich secreted protein, functions as an output molecule from the SCN circadian cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe00e8ac8dca61198c8cdab15936a10
https://pubmed.ncbi.nlm.nih.gov/12024199
https://pubmed.ncbi.nlm.nih.gov/12024199
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 25(7)
1. Mutations of residues in the third intracellular loops of several G-protein coupled receptors have been shown to confer constitutive activation. The authors investigated the effects of one such mutation in the dopamine D2 receptor. 2. Compared to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a973284f637ea3ee68e6da4889c14be3
https://pubmed.ncbi.nlm.nih.gov/11513354
https://pubmed.ncbi.nlm.nih.gov/11513354
Autor:
Cornelia Gorman, Clayton M. Bullock
Publisher Summary This chapter presents chloramphenicol acetyltransferase (CAT) as a gene expression tool, the system has been widely employed to characterize transfection techniques for tissues and cell lines, for characterizing DNA mutagenesis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607538040daa0ad7b3e3e9607308ce79
https://doi.org/10.1016/s0076-6879(00)26056-4
https://doi.org/10.1016/s0076-6879(00)26056-4
