Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Clayton Hudson"'
Autor:
Rebecca Ruhl, Shushan Rana, Katherine Kelley, Cristina Espinosa-Diez, Clayton Hudson, Christian Lanciault, Charles R. Thomas, V. Liana Tsikitis, Sudarshan Anand
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Colorectal cancer (CRC) is a leading cause of cancer-related death. The biologic response of CRC to standard of care adjuvant therapies such as chemotherapy and radiation are poorly understood. MicroRNAs (miRs) have been shown to
Externí odkaz:
https://doaj.org/article/84e12b3700074dae815f54c861942d61
Autor:
Namita Chatterjee, Sokchea Khou, Clayton Hudson, Anupriya Agarwal, Sudarshan Anand, Charles R. Thomas, Eugenia Fraile-Bethencourt, Cristina Espinosa-Diez, Shushan Rana, Rebecca Ruhl
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
UVaDOC: Repositorio Documental de la Universidad de Valladolid
Universidad de Valladolid
Scientific Reports
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
UVaDOC: Repositorio Documental de la Universidad de Valladolid
Universidad de Valladolid
Scientific Reports
Producción Científica
Activation of acid sphingomyelinase (SMPD1) and the generation of ceramide is a critical regulator of apoptosis in response to cellular stress including radiation. Endothelial SMPD1 has been shown to regulate tumor respon
Activation of acid sphingomyelinase (SMPD1) and the generation of ceramide is a critical regulator of apoptosis in response to cellular stress including radiation. Endothelial SMPD1 has been shown to regulate tumor respon
Autor:
Sudarshan Anand, Rebecca Ruhl, Clayton Hudson, Rishima Mukherjee, Marlee Feltham, RaeAnna Wilson, Cristina Espinosa-Diez
Publikováno v:
Circulation Research. 125
Radiation therapy is a big part of standard of care in oncology. However, in the long- term patients treated with radiation are at higher risk of suffering cardiovascular events. It is well described that the genotoxic stress induced by Ionizing radi
Autor:
Rebecca Ruhl, Cristina Espinosa-Diez, Sudarshan Anand, Clayton Hudson, Eugenia Fraile-Bethencourt
Publikováno v:
Cancer Research. 80:1423-1423
DNA damaging agents including ionizing radiation (IR) therapy are widely used in cancer patients. Previous studies have suggested that the tumor vasculature, specifically endothelial cell (ECs) dictate responses to IR. We recently showed how IR, amon
Autor:
Sudarshan Anand, RaeAnna Wilson, Clayton Hudson, Rebecca Ruhl, Rishima Mukherjee, Cristina Espinosa-Diez, Marlee Feltham
Changes in gene expression are key for the cells to adapt and response to intrinsic and extrinsic stimulus. It has been shown that genotoxic stress induces global hypomethylation as a result of decreased expression of DNA methyl transferases (DNMT).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2ce584dc5f1e06c0fe8ad90244cf38
https://doi.org/10.1101/442699
https://doi.org/10.1101/442699
Autor:
Christian Lanciault, Rebecca Ruhl, Charles R. Thomas, Shushan Rana, Katherine A. Kelley, V. Liana Tsikitis, Sudarshan Anand, Clayton Hudson, Cristina Espinosa-Diez
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Background Colorectal cancer (CRC) is a leading cause of cancer-related death. The biologic response of CRC to standard of care adjuvant therapies such as chemotherapy and radiation are poorly understood. MicroRNAs (miRs) have been shown to affect CR
Autor:
Rebecca Ruhl, Sudarshan Anand, Christian Lanciault, V. Liana Tsikitis, Shushan Rana, Charles R. Thomas, Katherine A. Kelley, Cristina Espinosa-Diez, Clayton Hudson
Colorectal cancer (CRC) is a leading cause of cancer-related death. The responses of CRC to standard of care adjuvant therapies such as radiation or chemotherapy are poorly understood. MicroRNAs (miRs) are small non-coding RNAs that affect gene expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d081abc48f57b0663b10dc1b929fcee1
https://doi.org/10.1101/136234
https://doi.org/10.1101/136234
Autor:
Namita Chatterjee, Cristina Espinosa-Diez, Erin Helms, Omar F. Khan, Sudarshan Anand, Clayton Hudson, Daniel G. Anderson, Rebecca Ruhl, RaeAnna Wilson, Christina Hipfinger
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 6, Pp 1-12 (2018)
Cell Death and Disease, Vol 9, Iss 6, Pp 1-12 (2018)
MicroRNAs contribute to biological robustness by buffering cellular processes from external perturbations. Here we report an unexpected link between DNA damage response and angiogenic signaling that is buffered by two distinct microRNAs. We demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4ac8a8251df0713d8ff21d8b4ba654