Eftilagimod Alpha (a Soluble LAG-3 Protein) Combined With Pembrolizumab in Second-Line Metastatic NSCLC Refractory to Anti–Programmed Cell Death Protein 1/Programmed Death-Ligand 1-Based Therapy: Final Results from a Phase 2 Study

Autor: Matthew G. Krebs, MD, Martin Forster, MD, PhD, Margarita Majem, MD, PhD, Julio Peguero, MD, Wade Iams, MD, Tim Clay, MD, Patricia Roxburgh, MD, PhD, Bernard Doger, MD, PhD, Pawan Bajaj, MD, Andres Barba, MD, Suvini Perera, MS, Christian Mueller, MS, Frédéric Triebel, MD, PhD

Publikováno v: JTO Clinical and Research Reports, Vol 5, Iss 11, Pp 100725- (2024)

Introduction: Eftilagimod alpha (efti), a soluble lymphocyte activation gene-3 protein, triggers antigen-presenting cell and T-cell (CD4+ and CD8+) activation and helps overcome resistance to programmed cell death protein 1 or programmed cell death-l

Externí odkaz: https://doaj.org/article/12c20e7bd714464f84bdef20677b2f93

LOREALAUS: LOrlatinib REAL-World AUStralian Experience in Advanced ALK-Rearranged NSCLC

Autor: Marliese Alexander, B.Pharm(Hons), MPH, PhD, Joe Wei, MD, Sagun Parakh, MD, Thomas John, MD, Steven Kao, MD, Adnan Nagrial, MD, Samantha Bowyer, MD, Lydia Warburton, MD, Melissa Moore, MD, Brett G.M. Hughes, MD, Timothy D. Clay, MD, Nick Pavlakis, MD, Benjamin J. Solomon, MD, Malinda Itchins, MD

Publikováno v: JTO Clinical and Research Reports, Vol 4, Iss 4, Pp 100490- (2023)

Introduction: Over the past decade, ALK tyrosine kinase inhibitors have delivered unprecedented survival for individuals with ALK-positive (ALK+) lung cancers. Real-world data enhance the understanding of optimal drug sequencing and expectations for

Externí odkaz: https://doaj.org/article/62a74cb698b1419b955b790acab4a2a3

Proximal tibial resorption in a modern total knee prosthesis

Autor: Justin T. Deen, MD, Terry B. Clay, MD, Dane A. Iams, MD, MaryBeth Horodyski, EdD, Hari K. Parvataneni, MD

Publikováno v: Arthroplasty Today, Vol 4, Iss 2, Pp 244-248 (2018)

Background: In an effort to minimize backside polyethylene wear and osteolysis associated with titanium tibial baseplates, many manufacturers have transitioned to cobalt chromium alloys. Recent literature has implicated thicker cobalt chromium design

Externí odkaz: https://doaj.org/article/42b27972fe2649128aed9a8163c63ad4

Asymptomatic facial papules and acrochordons of the thighs

Autor: Zabawski, Edward DO, Styles, Angela MD, Goetz, Dudley DO, Cockerell, Clay MD

Publikováno v: Zabawski, Edward DO; Styles, Angela MD; Goetz, Dudley DO; & Cockerell, Clay MD. (1997). Asymptomatic facial papules and acrochordons of the thighs. Dermatology Online Journal, 3(2). Retrieved from: http://www.escholarship.org/uc/item/14j9p2q4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::4b62e5cafd881a7d355e35c364d19bbe
http://www.escholarship.org/uc/item/14j9p2q4

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