Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Claus-Dieter Gerharz"'
Autor:
Anne M. Schultheis, Ino deBruijn, Pier Selenica, Gabriel S. Macedo, Edaise M. daSilva, Salvatore Piscuoglio, Achim A. Jungbluth, Kay J. Park, David S. Klimstra, Eva Wardelmann, Wolfgang Hartmann, Claus Dieter Gerharz, Mareike vonPetersdorff, Reinhard Buettner, Jorge S. Reis‐Filho, Britta Weigelt
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 833-845 (2022)
Small cell carcinoma (SCC) of the uterine cervix is a rare and aggressive form of neuroendocrine carcinoma, which resembles small cell lung cancer (SCLC) in its histology and poor survival rate. Here, we sought to define the genetic underpinning of S
Externí odkaz:
https://doaj.org/article/9522e16c4c97404e9c06171446460311
Autor:
Britta Weigelt, Gabriel S Macedo, Eva Wardelmann, Mareike von Petersdorff, Achim A. Jungbluth, Kay J. Park, Wolfgang Hartmann, David S. Klimstra, Salvatore Piscuoglio, Anne M. Schultheis, Edaise M da Silva, Claus Dieter Gerharz, Jorge S. Reis-Filho, Reinhard Buettner, Pier Selenica, Ino de Bruijn
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 833-845 (2022)
Small cell carcinoma (SCC) of the uterine cervix is a rare and aggressive form of neuroendocrine carcinoma, which resembles small cell lung cancer (SCLC) in its histology and poor survival rate. Here, we sought to define the genetic underpinning of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfc7a446668b364b700bcfcf62943ae
https://doi.org/10.1002/1878-0261.12962
https://doi.org/10.1002/1878-0261.12962
Autor:
Michael Untch, Peter Sinn, Winfried Koch, Claus Dieter Gerharz, Johannes Ammann, Hans Kreipe, Josef Rüschoff, S. Morris, Annette Lebeau
Publikováno v:
Modern Pathology. 30:217-226
Despite10 years of routine human epidermal growth factor receptor 2 (HER2) testing in breast cancer, testing quality is still an issue. Guidelines recommend assessing HER2 positivity rates as a quality indicator; however, the extent to which patient-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c968f3350377eda932449f822d127ae0
https://doi.org/10.1038/modpathol.2016.164
https://doi.org/10.1038/modpathol.2016.164
Autor:
Thomas Ruzicka, Michael Pohl, Rainer Koester, Helger Stege, Daniela Bruch-Gerharz, Jean Krutmann, Claus-Dieter Gerharz
Publikováno v:
Journal of the American Academy of Dermatology. 56:S21-S25
Background Gorham-Stout disease is an unusual, progressive syndrome of unknown etiology characterized by mono- or polyostotic osteolysis most often affecting children and young adults. The onset is insidious and the disease progresses to extensive an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85867cd7e5fe678450eaf93e47a62a2f
https://doi.org/10.1016/j.jaad.2006.01.063
https://doi.org/10.1016/j.jaad.2006.01.063
Autor:
Joerg Liebmann, Csaba Mahotka, Nils Wethkamp, Y Yan, T Shibata, Sebastian Heikaus, Christoph V. Suschek, Yu Guo, Claus-Dieter Gerharz, Helmut E. Gabbert, Uwe Ramp
Publikováno v:
British Journal of Cancer
Dysregulation of apoptosis plays an important role in tumour progression and resistance to chemotherapy. The X-linked inhibitor of apoptosis (XIAP) is considered to be the most potent caspase inhibitor of all known inhibitor of apoptosis-family membe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9797117859a070aa17eb2859b33312
https://doi.org/10.1038/sj.bjc.6602127
https://doi.org/10.1038/sj.bjc.6602127
Autor:
Csaba Mahotka, Sebastian Heikaus, Claus-Dieter Gerharz, E. Caliskan, Uwe Ramp, Helmut E. Gabbert, Arthur M. Krieg
Publikováno v:
British Journal of Cancer
TNF-related apoptosis-inducing ligand (TRAIL APO-2L) is a member of the TNF family and induces apoptosis in cancer cells without affecting most non-neoplastic cells. The present investigation is focused on apoptosis induction by combined exposure to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4c6347000f317cb60e1f9bf5f579b6
https://doi.org/10.1038/sj.bjc.6600984
https://doi.org/10.1038/sj.bjc.6600984
Autor:
Thomas Krieg, Uwe Ramp, Helmut E. Gabbert, Arthur M. Krieg, Claus-Dieter Gerharz, B Fang, Michael Wenzel, M Schmitt, Csaba Mahotka
Publikováno v:
British Journal of Cancer
Tumour necrosis factor (TNF) related apoptosis-inducing ligand (TRAIL/APO2L) is a recently identified member of the TNF family, which induces programmed cell death in a variety of neoplastic cell types, but not in most nonneoplastic cells. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f030d62a26f0a3873e6e713f26a22b70
https://doi.org/10.1038/sj.bjc.6600772
https://doi.org/10.1038/sj.bjc.6600772
Autor:
Thomas Krieg, H Grabsch, Arthur M. Krieg, S Takeno, Csaba Mahotka, Wolfram Müller, Manfred Heydthausen, Helmut E. Gabbert, Claus-Dieter Gerharz, Christoph V. Suschek
Publikováno v:
British Journal of Cancer
Survivin is a novel member of the inhibitor of apoptosis family and determines the susceptibility of tumour cells to pro-apoptotic stimuli. Recently, we identified two novel alternative splice variants of survivin, differing in their anti-apoptotic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49edbe07ca618055b1c1f6f0ca0e2670
https://doi.org/10.1038/sj.bjc.6600153
https://doi.org/10.1038/sj.bjc.6600153
Autor:
Uwe Ramp, C. Karagiannidis, Helmut E. Gabbert, Reinhardt Willers, E. Caliskan, Claus-Dieter Gerharz, Thomas Ebert
Publikováno v:
The Journal of Pathology. 196:430-436
Clear cell renal cell carcinomas (RCCs) are characterized by a deletion of chromosome 3p, which might result in the inactivation of the FHIT (fragile histidine triad) gene, a putative tumour suppressor gene. To explore the relevance of FHIT aberratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bea827ec51e41a0300b563555f3bd4
https://doi.org/10.1002/path.1062
https://doi.org/10.1002/path.1062
Autor:
Dietmar Simon, Claus-Dieter Gerharz, J. Witte, Achim Wolf, Kenko Cupisti, Peter E. Goretzki, Cornelia Dotzenrath, Hans-Dietrich Röher
Publikováno v:
Langenbeck's Archives of Surgery. 385:526-530
Background and aims: The surgical strategy in small sporadic C-cell carcinomas of the thyroid that are incidentally diagnosed after goiter resection for benign disease is controversial. It remains unclear whether a completion thyroidectomy should be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e177bed94aa560645ddaf6107a94ea66
https://doi.org/10.1007/s004230000166
https://doi.org/10.1007/s004230000166