Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Claus T. Christoffersen"'
Autor:
Lone Helboe, Nina Rosenqvist, Christiane Volbracht, Lars Ø. Pedersen, Jan T. Pedersen, Søren Christensen, Jan Egebjerg, Claus T. Christoffersen, Benny Bang-Andersen, Thomas G. Beach, Geidy E. Serrano, Jeppe Falsig
Publikováno v:
Journal of Alzheimer's Disease. 88:207-228
Background: Deposits of hyperphosphorylated tau fibrils are hallmarks of a broad spectrum of tauopathies, including Alzheimer’s disease (AD). Objective: To investigate heterogeneity of tau pathology across brain extracts from a broad selection of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b02055038581d809760d2e5e312230
https://doi.org/10.3233/jad-220125
https://doi.org/10.3233/jad-220125
Autor:
Paul Tempest, Chin‐Yin Tai, Maiko Ono, Marc B Skaddan, Kyle C Wilcox, Aimee Reed, Srirajan Vaidyanathan, Claus T Christoffersen, Pekka Kallunki, Benny Bang‐Andersen, Richard A Margolin, Tzu‐Huei Kao, Makoto Higuchi, Ming‐Kuei Jang
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dbbb2082a98dc64a4c481983ad9cd7c
https://doi.org/10.1002/alz.063036
https://doi.org/10.1002/alz.063036
Autor:
Alejandro, Castán, Ramón, Badorrey, José A, Díez, Claus T, Christoffersen, Lars K, Rasmussen, Jan, Kehler, Ralf, Köhler, José A, Gálvez, María D, Díaz-de-Villegas
Publikováno v:
The Journal of organic chemistry. 85(9)
Two series of novel chiral hexahydro-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57c3c0319bc75bcaf7501e2b68074278
https://pubmed.ncbi.nlm.nih.gov/32248689
https://pubmed.ncbi.nlm.nih.gov/32248689
Autor:
Poda Suresh Babu, Michelle A. Uberti, Arun Ranganathn, Michael Sabio, Claus T. Christoffersen, Veena Menon, Vincent H. Jorgensen, Kenneth A. Jones
Publikováno v:
ASSAY and Drug Development Technologies. 6:787-794
A luminescence assay using a new plate reader, the LumiLux (PerkinElmer, Waltham, MA), has been validated for high-throughput screening (HTS). In this study, we compared the aequorin luminescence-based calcium mobilization assay to the fluorescence-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2671105a552d9b37d214aa7192ea90
https://doi.org/10.1089/adt.2008.157
https://doi.org/10.1089/adt.2008.157
Autor:
Birgitte Ursø, Patricia A. Holst, Hans Tornqvist, David Naor, M. Mapoko Ilondo, Sophie Giorgetti, Claus T. Christoffersen, Margriet Ouwens, E Van Obberghen, Pierre De Meyts
Publikováno v:
Cellular Signalling. 15:385-394
Insulin and growth hormone (GH) induce mitogenic and metabolic signals in cells, GH either directly or indirectly via IGF-I production. We have studied a spontaneous murine T-cell lymphoma (LB cells) devoid of IGF-1 receptors in which proliferation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba996bd60feec08afd866e651a76de9
https://doi.org/10.1016/s0898-6568(02)00113-4
https://doi.org/10.1016/s0898-6568(02)00113-4
Autor:
Niels, Krogsgaard-Larsen, Anders A, Jensen, Tenna J, Schrøder, Claus T, Christoffersen, Jan, Kehler
Publikováno v:
Journal of medicinal chemistry. 57(13)
By introducing distal substituents on a tetracyclic scaffold resembling the ergoline structure, two series of analogues were achieved exhibiting subnanomolar receptor binding affinities for the dopamine D2 and serotonin 5-HT6 receptor subtype, respec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7e634fd367691827612dfcefd98e48a
https://pubmed.ncbi.nlm.nih.gov/24878269
https://pubmed.ncbi.nlm.nih.gov/24878269
Autor:
Birgitte Ursø, Frédéric P. Lemaigre, Hans Tornqvist, Ronald M. Shymko, Pierre De Meyts, Claus T. Christoffersen, Guy G. Rousseau, Christophe E. Pierreux
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 104:68-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6e00bc4f0d3565f40135338163589c
https://doi.org/10.1055/s-0029-1211548
https://doi.org/10.1055/s-0029-1211548
Autor:
Hans Tornqvist, Eberhard Heinze, Walter M. Teller, Martin Wabitsch, Per Bo Jensen, Wolfgang Rascher, Werner F. Blum, Claus T Christoffersen, P Englaro, Hans Hauner
Publikováno v:
Europe PubMed Central
The aim of this study was to investigate the regulation of leptin expression and production in cultured human adipocytes using the model of in vitro differentiated human adipocytes. Freshly isolated human preadipocytes did not exhibit significant lep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003f289f36a2f246e1552179c27df7b8
https://doi.org/10.2337/diab.45.10.1435
https://doi.org/10.2337/diab.45.10.1435
Autor:
Brenda Wallach, Karen Grønskov, Birgitte Ursø, Ronald M. Shymko, Claus T. Christoffersen, Fumiatsu Yakushiji, Pierre De Meyts
Publikováno v:
Metabolism. 44:2-11
The signal transduction pathways activated by hormones, growth factors, and cytokines show an extraordinary degree of cross-talk and redundancy. This review addresses the question of how the specificity conferred at the binding step is maintained thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05bda9c60ddbc8c22ddd07047df04eb
https://doi.org/10.1016/0026-0495(95)90214-7
https://doi.org/10.1016/0026-0495(95)90214-7
Autor:
Guri Tzivion, Dvorah Ish-Shalom, Birgitte Ursø, Pierre De Meyts, Claus T. Christoffersen, David Naor
Publikováno v:
Annals of the New York Academy of Sciences. 766:409-414
We have characterized an insulin-dependent T-cell lymphoma, LB, devoid of IGF-I receptor, which undergoes insulin stimulation and cell proliferation both in vitro and in vivo. In these cells, the mitogenic response can be evoked only through binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bab7075b98d61505d105dd61268a93
https://doi.org/10.1111/j.1749-6632.1995.tb26690.x
https://doi.org/10.1111/j.1749-6632.1995.tb26690.x