Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Claus Svarer"'
Autor:
Kamilla Woznica Miskowiak, Viktoria Damgaard, Johanna Mariegaard Schandorff, Julian Macoveanu, Gitte Moos Knudsen, Annette Johansen, Pontus Plaven-Sigray, Claus Svarer, Caroline Bruun Fussing, Katrine Cramer, Martin Balslev Jørgensen, Lars Vedel Kessing, Hannelore Ehrenreich
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Cognitive impairment is prevalent across neuropsychiatric disorders but there is a lack of treatment strategies with robust, enduring effects. Emerging evidence indicates that altitude-like hypoxia cognition training may induce lo
Externí odkaz:
https://doaj.org/article/a626539da28d4ef0a67f3810f3c6e4d5
Autor:
Anjali Sankar, Brice Ozenne, Vibeke H. Dam, Claus Svarer, Martin B. Jørgensen, Kamilla W. Miskowiak, Vibe G. Frokjaer, Gitte M. Knudsen, Patrick M. Fisher
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Brain serotonergic (5-HT) signaling is posited to modulate neural responses to emotional stimuli. Dysfunction in 5-HT signaling is implicated in major depressive disorder (MDD), a disorder associated with significant disturbances in emotion
Externí odkaz:
https://doaj.org/article/5a5bba0c78204720afbf354d09068022
Autor:
Kristin Köhler-Forsberg, Brice Ozenne, Søren V. Larsen, Asbjørn S. Poulsen, Elizabeth B. Landman, Vibeke H. Dam, Cheng-Teng Ip, Anders Jørgensen, Claus Svarer, Gitte M. Knudsen, Vibe G. Frokjaer, Martin B. Jørgensen
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Concurrent anxiety is frequent in major depressive disorder and a shared pathophysiological mechanism between anxiety and other depressive symptoms is plausible. The serotonin 4 receptor (5-HT4R) has been implicated in both depression and an
Externí odkaz:
https://doaj.org/article/124fc4cf19d349e0a5f8464a7acd6113
Autor:
Gjertrud Louise Laurell, Pontus Plavén-Sigray, Claus Svarer, R. Todd Ogden, Gitte Moos Knudsen, Martin Schain
Publikováno v:
NeuroImage, Vol 263, Iss , Pp 119620- (2022)
Molecular neuroimaging is today considered essential for evaluation of novel CNS drugs; it is used to quantify blood-brain barrier permeability, verify interaction with key target and determine the drug dose resulting in 50% occupancy, IC50. In spite
Externí odkaz:
https://doaj.org/article/fb55ae1d3f5f487b9b947c6edd72b463
Autor:
Søren Vinther Larsen, Brice Ozenne, Kristin Köhler-Forsberg, Asbjørn Seenithamby Poulsen, Vibeke Høyrup Dam, Claus Svarer, Gitte Moos Knudsen, Martin Balslev Jørgensen, Vibe Gedso Frokjaer
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundHormonal contraceptive (HC) use has been associated with an increased risk of developing a depressive episode. This might be related to HC’s effect on the serotonergic brain system as suggested by recent cross-sectional data from our grou
Externí odkaz:
https://doaj.org/article/d2c85266cc914d119155a330d6ba3888
Autor:
Nakul Ravi Raval, Arafat Nasser, Clara Aabye Madsen, Natalie Beschorner, Emily Eufaula Beaman, Morten Juhl, Szabolcs Lehel, Mikael Palner, Claus Svarer, Pontus Plavén-Sigray, Louise Møller Jørgensen, Gitte Moos Knudsen
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Positron emission tomography (PET) has become an essential clinical tool for diagnosing neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. Despite many attempts, it has not been possible to develop an appropriat
Externí odkaz:
https://doaj.org/article/f482c8b7afce44d5bff90eb3d037684f
Autor:
Martin Nørgaard, Vincent Beliveau, Melanie Ganz, Claus Svarer, Lars H Pinborg, Sune H Keller, Peter S Jensen, Douglas N. Greve, Gitte M. Knudsen
Publikováno v:
NeuroImage, Vol 232, Iss , Pp 117878- (2021)
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the human brain and plays a key role in several brain functions and neuropsychiatric disorders such as anxiety, epilepsy, and depression. For decades, several in vivo and ex vi
Externí odkaz:
https://doaj.org/article/d03bbbc3812b4e9abc8fe5b6bdce7aa2
Autor:
Helle G. Andersen, Jayachandra M. Raghava, Claus Svarer, Sanne Wulff, Louise B. Johansen, Patrick K. Antonsen, Mette Ø. Nielsen, Egill Rostrup, Anthony C. Vernon, Lars T. Jensen, Lars H. Pinborg, Birte Y. Glenthøj, Bjørn H. Ebdrup
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Patients with chronic schizophrenia often display enlarged striatal volumes, and antipsychotic drugs may contribute via the dopamine D2/3 receptor (D2/3R) blockade. Separating the effects of disease from medication is challenging due to the lack of a
Externí odkaz:
https://doaj.org/article/bf7facf14d5340eca56fdadecd72d8eb
Autor:
Vincent Beliveau, Brice Ozenne, Stephen Strother, Douglas N. Greve, Claus Svarer, Gitte Moos Knudsen, Melanie Ganz
Publikováno v:
NeuroImage, Vol 205, Iss , Pp 116240- (2020)
The human brain atlas of the serotonin (5-HT) system does not conform with commonly used parcellations of neocortex, since the spatial distribution of homogeneous 5-HT receptors and transporter is not aligned with such brain regions. This discrepancy
Externí odkaz:
https://doaj.org/article/d6708f4a19f34880944b93b846c54cc6
Autor:
Martin Nørgaard, Melanie Ganz, Claus Svarer, Patrick M. Fisher, Nathan W. Churchill, Vincent Beliveau, Cheryl Grady, Stephen C. Strother, Gitte M. Knudsen
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Background: Seasonal Affective Disorder (SAD) is a subtype of Major Depressive Disorder characterized by seasonally occurring depression that often presents with atypical vegetative symptoms such as hypersomnia and carbohydrate craving. It has recent
Externí odkaz:
https://doaj.org/article/89bd13ad4c4b499498db4c441a8bff4b