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Akademický článek
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Autor:
Volkhard Kurowski, Gertraud Neeser, Günter Pilz, O. Bujdoso, Peter Fraunberger, Burkhard Viell, Walter Marget, Roswita Neumann, Hans-Heinrich Osterhues, Roland Erich Schmieder, Norbert Speichermann, Margret Seewald, Karl Werdan, Ralph Stuttmann, Claus Peckelsen, Ursula Müller-Werdan, Ljiljana Verner, Peter Walger
Publikováno v:
Critical Care Medicine. 35:2693-2701
Objective: Intravenous immunoglobulin as an adjunctive treatment in sepsis was regarded as promising by a Cochrane metaanalysis of smaller trials. In this phase III multicenter trial, we assessed whether intravenous immunoglobulin G (ivIgG) reduced 2
Autor:
Daniel P. Rossignol, Melvyn Lynn, Kenneth Krell, Mary B. Roberts, Jean-Paul Mira, Janice L. Wheeler, Luis Jauregui, Mark Tidswell, Dominique Perrotin, Jan Pachl, Xavier Wittebole, Takahashi Takeshi, Derek C. Angus, Roland M. H. Schein, Jagadish Gogate, Edward Cordasco, Steven P. LaRosa, Andre C. Kalil, Jean Louis Vincent, Tatsuya Maruyama, Marc Van Nuffelen, Bruno François, Claus Peckelsen, Thierry Dugernier, Chia-Sheng Chang, Sandra Oeyen, Pierre-François Laterre, Naoki Aikawa, Steven M. Opal
Publikováno v:
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Importance Eritoran is a synthetic lipid A antagonist that blocks lipopolysaccharide (LPS) from binding at the cell surface MD2-TLR4 receptor. LPS is a major component of the outer membrane of gram-negative bacteria and is a potent activator of the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cc35bef8a4e55d0328a08b4157fea3
https://biblio.ugent.be/publication/4222072
https://biblio.ugent.be/publication/4222072
Autor:
Claus Peckelsen, James C. Stolzenbach, Ville Pettilä, Vincent Shu, Stuart Simon, Abla A. Creasey, Christopher J. Doig, Edward Abraham, Russell Postier, Bruce Light, Konrad Reinhart, Judy Stone, Herbert Spapen, Charles L. Sprung, Petr Svoboda, Lona Poole, Jeffrey Tobias, Sandra Percell, Steven M. Opal, Ignace Demeyer, Cathy De Deyne, Allan Seibert, Christian Zwingelstein, Antonio Artigas, Pierre-François Laterre, Angel López Rodriguez, Richard Beale
Publikováno v:
JAMA. 290(2)
Context The expression and release of tissue factor is a major trigger for the activation of coagulation in patients with sepsis. Tissue factor pathway inhibitor (TFPI) forms a complex with tissue factor and blood protease factors leading to inhibiti