Evaluation of an automated template-based treatment planning system for radiotherapy of anal, rectal and prostate cancer

Autor: Lucie Calmels, Patrik Sibolt, Lina M. Åström, Eva Serup-Hansen, Henriette Lindberg, Anna-Lene Fromm, Gitte Persson, David Sjöström, Poul Geertsen, Claus P. Behrens

Publikováno v: Technical Innovations & Patient Support in Radiation Oncology, Vol 22, Iss , Pp 30-36 (2022)

Background and purpose: The Ethos system has enabled online adaptive radiotherapy (oART) by implementing an automated treatment planning system (aTPS) for both intensity-modulated radiotherapy (IMRT) and volumetric modulated arc radiotherapy (VMAT) p

Externí odkaz: https://doaj.org/article/1351981945cd44b1b593f8fc4e003853

Clinical implementation of artificial intelligence-driven cone-beam computed tomography-guided online adaptive radiotherapy in the pelvic region

Autor: Patrik Sibolt, Lina M. Andersson, Lucie Calmels, David Sjöström, Ulf Bjelkengren, Poul Geertsen, Claus F. Behrens

Publikováno v: Physics and Imaging in Radiation Oncology, Vol 17, Iss , Pp 1-7 (2021)

Background and purpose: Studies have demonstrated the potential of online adaptive radiotherapy (oART). However, routine use has been limited due to resource demanding solutions. This study reports on experiences with oART in the pelvic region using

Externí odkaz: https://doaj.org/article/f1b472a639964fc29306dbd03eecfb46

Online adaptive radiotherapy of urinary bladder cancer with full re-optimization to the anatomy of the day:initial experience and dosimetric benefits

Autor: Lina M. Åström, Claus P. Behrens, Lucie Calmels, David Sjöström, Poul Geertsen, Lene Sonne Mouritsen, Eva Serup-Hansen, Henriette Lindberg, Patrik Sibolt

Publikováno v: Åström, L M, Behrens, C P, Calmels, L, Sjöström, D, Geertsen, P, Mouritsen, L S, Serup-Hansen, E, Lindberg, H & Sibolt, P 2022, ' Online adaptive radiotherapy of urinary bladder cancer with full re-optimization to the anatomy of the day : initial experience and dosimetric benefits ', Radiotherapy and Oncology, vol. 171, pp. 37-42 . https://doi.org/10.1016/j.radonc.2022.03.014

Background and purpose: Online adaptive radiotherapy (oART) potentially reduces the dose to organs at risk (OARs) as the planning target volume (PTV) margins are reduced compared to a nonadaptive approach (non-ART). This study evaluates the feasibili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::facf8eafe789387320a3a8157a4144f0
https://orbit.dtu.dk/en/publications/e34f43b4-b88f-49d5-b3dc-df0dc7efecc3

Robust extraction of biological information from diffusion-weighted magnetic resonance imaging during radiotherapy using semi-automatic delineation

Autor: Anne Louise Højmark Bisgaard, Carsten Brink, Maja Lynge Fransen, Tine Schytte, Claus P. Behrens, Ivan Vogelius, Henrik Dahl Nissen, Faisal Mahmood

Publikováno v: Bisgaard, A L H, Brink, C, Fransen, M L, Schytte, T, Behrens, C P, Vogelius, I, Nissen, H D & Mahmood, F 2022, ' Robust extraction of biological information from diffusion-weighted magnetic resonance imaging during radiotherapy using semi-automatic delineation ', Physics and Imaging in Radiation Oncology, vol. 21, pp. 146-152 . https://doi.org/10.1016/j.phro.2022.02.014
Bisgaard, A L H, Brink, C, Fransen, M L, Schytte, T, Behrens, C F, Vogelius, I R, Nissen, H D & Mahmood, F 2022, ' Robust extraction of biological information from diffusion-weighted magnetic resonance imaging during radiotherapy using semi-automatic delineation ', Physics and Imaging in Radiation Oncology, vol. 21, pp. 146-152 . https://doi.org/10.1016/j.phro.2022.02.014

Background and purposeDiffusion-Weighted Magnetic Resonance imaging (DWI) quantifies water mobility through the Apparent Diffusion Coefficient (ADC), a promising radiotherapy response biomarker. ADC measurements depend on manual delineation of a regi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57b167191372cf5c1b8b175ba97626c
https://pubmed.ncbi.nlm.nih.gov/35284662

Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer

Autor: Astrid Zedlitz Johansen, Marco Carretta, Marie-Louise Thorseth, Shawez Khan, Klaire Yixin Fjæstad, Christian Beltoft Brøchner, Hannes Linder, Christina Ankjærgaard, Marco Donia, Inna Chen, Dorte Lisbet Nielsen, Claus Preibisch Behrens, Daniel Hargbøl Madsen

Publikováno v: Pharmaceutics, Vol 14, Iss 5, p 1046 (2022)

YKL-40 (also named chitinase 3 like-1 protein [CHI3L1]) is a secreted chitinase-like protein which is upregulated in cancers and suggested to have pro-tumorigenic activity. YKL-40 lacks enzymatic function, but it can bind carbohydrates such as chitin

Externí odkaz: https://doaj.org/article/78186d8268bd442d8ea8f1b9fe7ac71e