Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Claus P. Schmitt"'
Autor:
Katharina Küper, Gernot Poschet, Julia Rossmann, Sven F. Garbade, Alexander Spiegelhalter, Dan Wen, Georg F. Hoffmann, Claus P. Schmitt, Thomas Opladen, Verena Peters
Publikováno v:
Amino Acids, Vol 57, Iss 1, Pp 1-9 (2024)
Abstract Dipeptides (DPs), composed of two amino acids (AAs), hold significant therapeutic potential but remain underexplored. Given the crucial role of AAs in central nervous system (CNS) function, this study investigated the presence of DPs in cere
Externí odkaz:
https://doaj.org/article/e34278e04c2143718b47eee2a341b637
Autor:
Charlotte Wetzel, Nadia Gallenstein, Verena Peters, Thomas Fleming, Iva Marinovic, Alea Bodenschatz, Zhiwei Du, Katharina Küper, Clelia Dallanoce, Giancarlo Aldini, Thomas Schmoch, Thorsten Brenner, Markus Alexander Weigand, Sotirios G. Zarogiannis, Claus Peter Schmitt, Maria Bartosova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Integrity of epithelial and endothelial cell barriers is of critical importance for health, barrier disruption is a hallmark of numerous diseases, of which many are driven by carbonyl stressors such as methylglyoxal (MG). Carnosine and anser
Externí odkaz:
https://doaj.org/article/70301e72d8d747ad8403c2250f094006
Autor:
Eszter Levai, Iva Marinovic, Maria Bartosova, Conghui Zhang, Betti Schaefer, Hanna Jenei, Zhiwei Du, Dorota Drozdz, Günter Klaus, Klaus Arbeiter, Philipp Romero, Vedat Schwenger, Constantin Schwab, Attila J. Szabo, Sotirios G. Zarogiannis, Claus Peter Schmitt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Next to the skin, the peritoneum is the largest human organ, essentially involved in abdominal health and disease states, but information on peritoneal paracellular tight junctions and transcellular channels and transporters relative to peri
Externí odkaz:
https://doaj.org/article/69950bb762e74cee9493f0850e9d668b
Autor:
Morgane Mazzarino, Esra Cetin, Maria Bartosova, Iva Marinovic, Natacha Ipseiz, Timothy R. Hughes, Claus Peter Schmitt, Dipak P. Ramji, Mario O. Labéta, Anne-Catherine Raby
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chronic Kidney Disease (CKD) is associated with markedly increased cardiovascular (CV) morbidity and mortality. Chronic inflammation, a hallmark of both CKD and CV diseases (CVD), is believed to drive this association. Pro-inflammatory endogenous TLR
Externí odkaz:
https://doaj.org/article/3289f0a2df684724b686b25645161512
Autor:
Maria Bartosova, Sotirios G. Zarogiannis, Claus Peter Schmitt, for the Members of the International Pediatric Peritoneal Biobank
Publikováno v:
Molecular and Cellular Pediatrics, Vol 9, Iss 1, Pp 1-10 (2022)
Abstract Children with chronic kidney disease (CKD) suffer from inflammation and reactive metabolite-induced stress, which massively accelerates tissue and vascular aging. Peritoneal dialysis (PD) is the preferred dialysis mode in children, but curre
Externí odkaz:
https://doaj.org/article/52d16b14d3d946d3ae6dc73343972451
Autor:
Tilman Pfeffer, Charlotte Wetzel, Philip Kirschner, Maria Bartosova, Tanja Poth, Constantin Schwab, Gernot Poschet, Johanna Zemva, Ruben Bulkescher, Ivan Damgov, Christian Thiel, Sven F. Garbade, Kristina Klingbeil, Verena Peters, Claus Peter Schmitt
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1270 (2023)
Carnosine and anserine supplementation markedLy reduce diabetic nephropathy in rodents. The mode of nephroprotective action of both dipeptides in diabetes, via local protection or improved systemic glucose homeostasis, is uncertain. Global carnosinas
Externí odkaz:
https://doaj.org/article/718e352e79ad48998cdac09e86c71743
Autor:
Christina Taylan, Anne Schaaf, Corina Dorn, Claus Peter Schmitt, Sebastian Loos, Nele Kanzelmeyer, Lars Pape, Dominik Müller, Lutz T. Weber, Julia Thumfart
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundTherapeutic apheresis (TA) is based on the principles of either removing dissolved pathogenic substances (e.g., antibodies) from the blood plasma or replacing plasma factors. It expands the therapeutic scope for a variety of diseases. Safet
Externí odkaz:
https://doaj.org/article/5cce7189863b45aeaf783dfa45a982fa
Autor:
Rusan Ali Catar, Maria Bartosova, Edyta Kawka, Lei Chen, Iva Marinovic, Conghui Zhang, Hongfan Zhao, Dashan Wu, Daniel Zickler, Honorata Stadnik, Marek Karczewski, Julian Kamhieh-Milz, Achim Jörres, Guido Moll, Claus Peter Schmitt, Janusz Witowski
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Peritoneal dialysis (PD) is a valuable ‘home treatment’ option, even more so during the ongoing Coronavirus pandemic. However, the long-term use of PD is limited by unfavourable tissue remodelling in the peritoneal membrane, which is associated w
Externí odkaz:
https://doaj.org/article/5d5b9dd4d4a64992aac0d24af8da1854
Autor:
Ariane Zaloszyc, Claus Peter Schmitt, Amira Sayeh, Laetitia Higel, Catherine-Isabelle Gros, Fabien Bornert, Gaëlle Aubertin-Kirch, Jean-Philippe Dillenseger, Christian Goetz, André Constantinesco, Michel Fischbach, Seiamak Bahram, Philippe Choquet
Publikováno v:
PeerJ, Vol 9, p e12355 (2021)
Background To provide insight into bone turnover, quantitative measurements of bone remodeling are required. Radionuclide studies are widely used in clinical care, but have been rarely used in the exploration of the bone in preclinical studies. We de
Externí odkaz:
https://doaj.org/article/ae18fe3a4c4b47049342bf151028b131
Autor:
Charlotte Wetzel, Tilman Pfeffer, Ruben Bulkescher, Johanna Zemva, Sergio Modafferi, Alessandra Polimeni, Angela Trovato Salinaro, Vittorio Calabrese, Claus Peter Schmitt, Verena Peters
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 66 (2022)
Anserine and carnosine have nephroprotective actions; hydrogen sulfide (H2S) protects from ischemic tissue damage, and the underlying mechanisms are debated. In view of their common interaction with HSP70, we studied possible interactions of both dip
Externí odkaz:
https://doaj.org/article/cbf7c018f8434f9390ef6096ec516f5d