Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Claus Moritz Graef"'
Autor:
Claus Moritz Graef, Philipp Gödel, Philipp Falderbaum, Hyatt Balke‐Want, Florian Simon, Noëlle Sieg, Jan‐Hendrik Naendrup, Marie Anne‐Catherine Neumann, Sarah Gillessen, Paul J. Bröckelmann, Dennis A. Eichenauer, Peter Borchmann, Bastian Tresckow, Jan‐Michel Heger
Publikováno v:
European journal of haematologyREFERENCES. 108(5)
Background Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) are aggressive B-cell non-Hodgkin lymphomas (B-NHL) with a generally favorable prognosis after immunochemotherapy. The outcome of BL is superior to DLBCL. In 2016, a distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d35519f2eedd643bb26643cc54df96d
https://pubmed.ncbi.nlm.nih.gov/35090068
https://pubmed.ncbi.nlm.nih.gov/35090068
Autor:
Gerald A. Grant, Siddhartha Mitra, Orly Liba, Rebecca Dutta, Samuel H. Cheshier, Claus Moritz Graef, Adam de la Zerda, Elliott D. SoRelle, Derek Yecies, Frederick Christian Bennett, Lydia-Marie Joubert
Publikováno v:
ACS Nano. 13:7985-7995
By their nature, tumors pose a set of profound challenges to the immune system with respect to cellular recognition and response coordination. Recent research indicates that leukocyte subpopulations, especially tumor-associated macrophages (TAMs), ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d44153fa3c5ee32c013e7ce9851c3aa
https://doi.org/10.1021/acsnano.9b02656
https://doi.org/10.1021/acsnano.9b02656
Autor:
Johanna Theruvath, Suzana Assad Kahn, Michael Zhang, Eva Maria Manz, Tej D. Azad, Gregor Hutter, Carmel T. Chan, Gerald A. Grant, Siddhartha Mitra, Andrew Olson, Samuel H. Cheshier, Claus Moritz Graef, Sharareh Gholamin, Irving L. Weissman, Rahul Sinha, Joy Q He, Matthew K. Schoen, Christy Wilson, Mariko L. Bennett
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tumor-associated microglia and macrophages (TAMs) constitute up to one half of the cells in glioblastoma multiforme (GBM) and are known to promote tumor growth. Therefore, modulation and reeducation of the TAM pool is a promising antitum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a246c601cf67b43c52dd284663aaf1
http://europepmc.org/articles/PMC6338872
http://europepmc.org/articles/PMC6338872
Autor:
Shaurya Dhingra, Samuel H. Cheshier, Sabine Mueller, Stéphanie Puget, Marcel Kool, Siddhartha Mitra, Derek Yecies, Olivier Delattre, Michael C. Frühwald, Johanna Theruvath, Christopher Mount, Robbie G. Majzner, Sakina Zaidi, Didier Surdez, Louai Labanieh, Daniel Williamson, Poul H. Sorensen, Amaury Leruste, Franck Bourdeaut, Claus Moritz Graef, Alberto Delaidelli, Pascal Johann, Crystal L. Mackall, Michelle Monje, Elena Sotillo, Stefan M. Pfister, Sabine Heitzeneder, Peng Xu, Martin Hasselblatt, Martina Finetti
Publikováno v:
Nat Med
Atypical teratoid/rhabdoid tumors (ATRTs) typically arise in the central nervous system (CNS) of children under 3 years of age. Despite intensive multimodal therapy (surgery, chemotherapy and, if age permits, radiotherapy), median survival is 17 mont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec562df3042d0e34b5ccbb1718d69d97
https://europepmc.org/articles/PMC7992505/
https://europepmc.org/articles/PMC7992505/
Autor:
Peter Borchmann, Jan-Hendrik Naendrup, Paul J Bröckelmann, Noëlle Sieg, Hyatt Balke-Want, Florian Simon, Philipp Gödel, Claus Moritz Graef, Marie Anne-Catherine Neumann, Sarah Gillessen, Philipp Falderbaum, Jan-Michel Heger, Bastian von Tresckow, Dennis A. Eichenauer
Publikováno v:
Blood. 138:2531-2531
Background: The genetic hallmark of BL is MYC gene rearrangement. However, due to histopathological, immunohistochemical and cytogenetic similarities, differentiation from Diffuse Large B-Cell Lymphoma (DLBCL) remains challenging in some cases. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e2e2d1309d7bade43a08ed06baa7f1f
https://doi.org/10.1182/blood-2021-145283
https://doi.org/10.1182/blood-2021-145283
Autor:
Elliott Daniel, SoRelle, Derek William, Yecies, Orly, Liba, Frederick Christian, Bennett, Claus Moritz, Graef, Rebecca, Dutta, Siddhartha, Mitra, Lydia-Marie, Joubert, Samuel, Cheshier, Gerald A, Grant, Adam, de la Zerda
Publikováno v:
ACS Nano
By their nature, tumors pose a set of profound challenges to the immune system with respect to cellular recognition and response coordination. Recent research indicates that leukocyte subpopulations, especially tumor-associated macrophages (TAMs), ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9e98ca966614af5fd33344fd4913794
https://pubmed.ncbi.nlm.nih.gov/31259527
https://pubmed.ncbi.nlm.nih.gov/31259527
Autor:
Johanna Theruvath, Louai Labanieh, Robbie G. Majzner, Crystal L. Mackall, Claus Moritz Graef, Sabine Heitzeneder
Efficient trafficking and infiltration of CAR T cells to brain tumors is an important determinant of treatment success. Data comparing the route of delivery for CAR-T cells in CNS malignancies is limited, but crucial for successful clinical trial des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6963dbfbf64cdfce5514a64c154790da
https://europepmc.org/articles/PMC6477526/
https://europepmc.org/articles/PMC6477526/
Autor:
Jarrett Rosenberg, Siddhartha Mitra, Laura Pisani, Claus Moritz Graef, Samuel H. Cheshier, Olga Lenkov, Hossein Nejadnik, Heike E. Daldrup-Link, Johanna Theruvath, Ketan Yerneni, Alejandro Sweet Cordero, Suchismita Mohanty
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 2, Pp 1-14 (2019)
Cell Death and Disease, Vol 10, Iss 2, Pp 1-14 (2019)
CD47 monoclonal antibodies (mAbs) activate tumor-associated macrophages (TAMs) in sarcomas to phagocytose and eliminate cancer cells. Though CD47 mAbs have entered clinical trials, diagnostic tests for monitoring therapy response in vivo are currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1277dae4dd59fa8cd2dabdf6d5c8e3d7
http://europepmc.org/articles/PMC6367456
http://europepmc.org/articles/PMC6367456
Autor:
Elena Sotillo, Claus Moritz Graef, Robbie G. Majzner, Sabine Heitzeneder, Louai Labanieh, Johanna Theruvath, Crystal L. Mackall
Publikováno v:
Cancer Research. 80:PR04-PR04
Atypical teratoid/rhabdoid tumors (ATRT) are highly malignant embryonal brain tumors, arising in very young children, and are associated with inactivation of SMARCB1. The prognosis is extremely poor. Hence new treatments are urgently needed. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218591f282ccec516bf04755fa2da361
https://doi.org/10.1158/1538-7445.pedca19-pr04
https://doi.org/10.1158/1538-7445.pedca19-pr04
Autor:
Gerald A. Grant, Orly Liba, Claus-Moritz Graef, Adam de la Zerda, Rebecca Dutta, Siddhartha Mitra, Elliott D. SoRelle, Lydia-Marie Joubert, Samuel H. Cheshier, Chris F Bennett, Derek Yecies
Leukocyte populations, especially tumor-associated macrophages (TAMs), are capable of mediating both anti- and pro-tumor processes and play significant roles in the tumor microenvironment. Moreover, TAMs have been shown to exert substantial influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5892ea962e5f8d60db0d5f2da98c351a